Cytarabine

In June 2025, several breakthrough drugs received their first global approvals and market launches, marking significant advances in therapeutic innovation. 1. Genakumab (Firsekibart) Firsekibart (Genakumab), developed by Changchun Genescience Pharmaceutical, is a fully human monoclonal antibody targeting interleukin-1β (IL-1β). It functions as an IL-1β inhibitor and was approved in China on June 30, 2025, for the treatment of gouty arthritis, especially in patients who are intolerant or unresponsive to NSAIDs or colchicine. The approval addresses a significant gap in long-acting, targeted anti-inflammatory therapies in China, offering a new option for over 14 million gout patients. Gout is a chronic inflammatory disease caused by urate crystal deposition in joints. It is often referred to as the "king of pain" due to its severe and recurrent attacks. The underlying pathology involves activation of the NLRP3 inflammasome in macrophages, leading to a surge in IL-1β secretion, which triggers a cascade of inflammatory responses. Firsekibart is a fully human anti-IL-1β monoclonal antibody that binds specifically to IL-1β and neutralizes its biological activity, blocking receptor interaction and suppressing inflammation at its source. This mechanism allows for rapid pain relief during acute attacks and sustained anti-inflammatory effects during intercritical periods, helping reduce recurrence rates and inflammatory flares during urate-lowering therapy. It may also offer systemic benefits for cardiorenal and metabolic comorbidities. The approval was based on data from a randomized, double-blind, multicenter Phase III trial involving 313 patients with acute gout flares. Results showed that a single dose of Firsekibart provided pain relief within 6 hours, with a comparable 72-hour efficacy to compound betamethasone. The primary endpoint—the difference in VAS pain score at 72 hours—was -3.32 mm (95% CI: -7.56, 0.91), confirming non-inferiority. Notably, Firsekibart demonstrated superior performance in preventing recurrence: ·Median time to first gout recurrence: not reached (Firsekibart) vs. 45 days (steroid group) ·Risk reduction in first recurrence within 6 months: up to 90% ·Recurrence reduction over 24 weeks: 87%, with 85.3% of patients remaining recurrence-free—the best result among its class. The drug was well tolerated, with a treatment-related adverse event rate similar to the control group and no serious adverse events reported. Future indications for Firsekibart may include cardiovascular inflammation, osteoarthritis, diabetes, obesity, and tumor microenvironment modulation, suggesting broad clinical potential. 2. Gemcitabine (AVGEMSI, D07001-Softgel) Gemcitabine, a small-molecule chemotherapeutic agent originally developed by FUJIFILM Corporation, received its first approval in the United States on June 27, 2025, for the treatment of multiple malignancies, and was granted orphan drug designation. Gemcitabine is a pyrimidine-based antitumor drug with a mechanism of action similar to cytarabine (Ara-C). It is activated intracellularly by deoxycytidine kinase (dCK) and metabolized by cytidine deaminase. Once metabolized, its active form incorporates into DNA during the G1/S phase, inhibiting DNA synthesis. Unlike cytarabine, gemcitabine also inhibits ribonucleotide reductase, decreasing intracellular dNTP pools and further impairing DNA replication. Additionally, it inhibits deoxycytidine deaminase, reducing the degradation of its own active metabolites—effectively self-potentiating its efficacy. These pharmacodynamic features give gemcitabine a broader antitumor spectrum than cytarabine, and it has demonstrated efficacy across multiple solid tumors, including metastatic breast cancer, non-small cell lung cancer (NSCLC), ovarian cancer, and pancreatic adenocarcinoma. Clinically, gemcitabine has become a standard first-line therapy for locally advanced and metastatic NSCLC. A pivotal Phase III trial in advanced NSCLC patients showed that the gemcitabine + cisplatin combination significantly improved overall survival compared to cisplatin alone: ·Median OS: 10.7 months (combination) vs. 8.6 months (cisplatin monotherapy) ·The difference was statistically significant (p < 0.05) Gemcitabine’s safety profile has been extensively studied. While myelosuppression, gastrointestinal discomfort, and fever are common adverse effects, they are generally manageable and acceptable, confirming the drug’s suitability for routine clinical use in oncology. 3. Mazdutide (IBI362) Mazdutide (also known as IBI362) is a synthetic polypeptide drug co-developed by Eli Lilly & Co. and Innovent Biologics. It acts as a dual agonist of GLP-1 and GIP receptors, designed for the treatment of endocrine and metabolic disorders. On June 24, 2025, it received its first market approval in China, with an indication for obesity and overweight. The drug also shows promising potential in other metabolic conditions such as type 2 diabetes, obstructive sleep apnea, non-alcoholic steatohepatitis (NASH), and various forms of heart failure. Mazdutide exerts synergistic effects by simultaneously activating GLP-1 and glucagon (GCG) receptors. Activation of GLP-1 receptors delays gastric emptying, suppresses appetite, and enhances satiety, leading to reduced caloric intake. Activation of the GCG receptor promotes lipolysis and increases energy expenditure, thereby enhancing weight loss. This dual mechanism provides superior efficacy compared to single-target agents, positioning Mazdutide as a representative of next-generation metabolic regulators. Clinical studies in Chinese populations have demonstrated significant weight loss and good safety. The pivotal Phase III GLORY-1 trial, published in the New England Journal of Medicine (NEJM), enrolled 610 Chinese subjects who were overweight or obese. After 48 weeks of once-weekly subcutaneous injections, the 4 mg group experienced a mean weight loss of 11.00%, and the 6 mg group lost 14.01%, compared to 0.3% in the placebo group. Notably, nearly 50% of patients in the 6 mg group achieved at least 15% body weight reduction, with effects evident as early as week 32. Beyond weight reduction, Mazdutide also improved glycemic control, lipid profiles, and blood pressure, making it particularly beneficial for Chinese patients with metabolic syndrome. In terms of safety, Mazdutide was well tolerated. The most common adverse events were mild to moderate gastrointestinal symptoms, including nausea, vomiting, and diarrhea, which mostly occurred during early treatment and resolved over time. The once-weekly injection regimen enhances patient adherence and supports long-term disease management. 4. Tetravalent Influenza Vaccine Developed by Fosun Apexvac (Dalian) Biopharmaceutical Co., Ltd., the tetravalent split inactivated influenza vaccine was first approved in China on June 17, 2025, for the prevention of influenza virus infection. The vaccine is produced using internationally standardized embryonated egg-based manufacturing techniques, free from antibiotics and preservatives, and provides broad protection by inducing immunity against four different influenza virus strains. Influenza is an acute respiratory infectious disease caused by influenza viruses. Due to the virus’s high genetic variability and broad host range, it spreads easily among humans, resulting in 3–5 million severe cases and 290,000–650,000 deaths globally each year. The World Health Organization (WHO) emphasizes that vaccination is the most effective method for influenza prevention, especially for high-risk individuals and their close contacts. This tetravalent vaccine contains inactivated antigens from four influenza strains: two A subtypes (e.g., H1N1 and H3N2) and two B lineages. The viruses are chemically split to release key antigens, such as hemagglutinin (HA) and neuraminidase (NA), which trigger immune responses. Upon administration, antigen-presenting cells (e.g., dendritic cells) process these viral antigens and present them to helper T cells, which in turn activate B cells to produce strain-specific antibodies—especially anti-HA antibodies capable of neutralizing the virus. The vaccine also induces memory B and T cells, enabling rapid immune responses upon future exposure to similar strains. 5. 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197, TT) The 13-valent pneumococcal polysaccharide conjugate vaccine, developed by CanSino Biologics, was first approved in China on June 17, 2025, for the prevention of Streptococcus pneumoniae infections. This multivalent conjugate vaccine targets 13 distinct pneumococcal serotypes responsible for pneumonia, meningitis, septicemia, and other invasive diseases. The vaccine functions by covalently linking capsular polysaccharide antigens of pneumococcal serotypes to protein carriers such as CRM197 (a non-toxic diphtheria toxin mutant) and tetanus toxoid (TT). This conjugation converts the normally T cell-independent polysaccharides into T cell-dependent antigens, capable of eliciting a stronger and longer-lasting immune response, particularly in infants and young children. After administration, the conjugated antigens are taken up and processed by antigen-presenting cells, then presented to CD4+ T helper cells, which activate B cells to generate serotype-specific antibodies. Additionally, the vaccine promotes the formation of memory B cells, providing long-term protection. This mechanism enables the immune system to mount a robust defense against the 13 pneumococcal serotypes, significantly reducing the risk of invasive pneumococcal disease (IPD). The vaccine is especially effective in pediatric populations, offering enhanced and durable immunity. 6. Garadacimab Garadacimab (formerly CSL312) is a fully human recombinant IgG4/λ monoclonal antibody developed by CSL Behring LLC. It was approved in the United States on June 16, 2025, for the treatment of hereditary angioedema (HAE), with additional potential applications in diseases such as idiopathic pulmonary fibrosis. HAE is a rare but potentially life-threatening genetic disorder that affects approximately 1 in 50,000 individuals. It is characterized by recurrent, painful episodes of swelling (angioedema), which can involve the larynx, gastrointestinal tract, and other critical areas. Garadacimab exerts its therapeutic effect by selectively binding to and inhibiting coagulation factor XIIa (FXIIa), a key initiator in the contact activation system involved in inflammatory and coagulation cascades. By targeting FXIIa, Garadacimab helps reduce pathological processes such as vascular leakage and inflammation, which are central to HAE pathogenesis. FXII is particularly important in HAE patients due to its role in activating the kallikrein-kinin system, leading to bradykinin-mediated angioedema. Garadacimab features an unusually long CDR-H3 loop, allowing specific binding to the β-chain of FXIIa, thereby blocking its protease activity and downstream pro-inflammatory and pro-coagulant pathways. The FDA approval was supported by efficacy and safety data from the pivotal Phase III VANGUARD trial (NCT04656418) and its open-label extension (NCT04739059). VANGUARD evaluated Garadacimab as a routine prophylactic treatment in 64 patients aged ≥12 years with Type I or II HAE, all of whom experienced ≥2 attacks during the run-in period and discontinued prior prophylactic therapies. Participants were randomized 3:2 to receive 400 mg loading dose followed by 200 mg monthly Garadacimab (n=39) or matched placebo (n=25) for 6 months. On-demand medication for breakthrough attacks was allowed. At baseline, 59.4% of participants had ≥3 HAE attacks per month (mean: 3.07/month in the Garadacimab group vs. 2.52/month in the placebo group). Garadacimab significantly reduced attack frequency and demonstrated a favorable safety profile, reinforcing its potential as a long-term preventive therapy for HAE. Additional trials in fibrotic and inflammatory diseases are ongoing, highlighting its broad therapeutic promise. 7. Taletrectinib Taletrectinib, also known by its compound name ADCT-601 or AnHeart Therapeutics' ROS1 inhibitor, is a next-generation small molecule tyrosine kinase inhibitor (TKI) targeting ROS1-positive non-small cell lung cancer (NSCLC). Co-developed by AnHeart Therapeutics (Hangzhou) and Innovent Biologics, Taletrectinib received FDA approval on June 11, 2025, for the treatment of locally advanced or metastatic ROS1-positive NSCLC. ROS1 gene rearrangements are oncogenic drivers found in approximately 1–2% of NSCLC cases and are associated with poor response to standard chemotherapy. Taletrectinib is a highly potent and selective ROS1 TKI, designed to inhibit the aberrant signaling caused by ROS1 fusions, which drive tumor growth in affected patients. Notably, it also shows efficacy against certain resistance mutations, offering therapeutic options for both treatment-naïve patients and those with acquired resistance to first-generation ROS1 inhibitors like crizotinib. FDA approval was based on results from two pivotal Phase II global multicenter studies, TRUST-I and TRUST-II, which evaluated the efficacy and safety of Taletrectinib in ROS1-positive advanced NSCLC across both treatment-naïve and pretreated populations. Patients received 600 mg orally once daily, and endpoints included objective response rate (ORR), duration of response (DoR), progression-free survival (PFS), and intracranial response in patients with brain metastases. Taletrectinib demonstrated robust clinical activity in both cohorts. It achieved high ORR, prolonged PFS, and demonstrated notable intracranial efficacy, making it a strong candidate for managing CNS-involved disease. Safety outcomes were favorable, with manageable adverse events, supporting its use as a next-generation targeted therapy for ROS1-positive NSCLC. Its ability to overcome resistance mechanisms further positions it as a valuable treatment option for patients who have progressed on earlier ROS1-targeted agents. 8. Clesrovimab Clesrovimab (MK-1654), developed by Merck Sharp & Dohme Corp., is a long-acting monoclonal antibody that received its first FDA approval on June 9, 2025, for the prevention of respiratory syncytial virus (RSV) infection. Clesrovimab specifically targets the RSV fusion (F) protein, a critical viral surface protein required for viral entry into host cells. By binding with high affinity to the F protein, Clesrovimab not only blocks the fusion process between the virus and host cell membranes—thereby preventing viral entry—but also enhances the immune system’s ability to recognize and eliminate the virus. Importantly, since the F protein is highly conserved across all RSV subtypes, Clesrovimab exhibits broad-spectrum antiviral activity against a wide range of RSV strains. As a passive immunization therapy, Clesrovimab’s extended half-life allows it to deliver direct, rapid, and long-lasting protection against RSV infection in healthy preterm infants, full-term infants, and high-risk infants. The antibody is designed to protect infants during their first RSV season against mild, moderate, and severe RSV disease. Data from the pivotal Phase 2b/3 CLEVER trial demonstrated that a single dose of Clesrovimab reduced medically attended RSV lower respiratory tract infections by 60.5% and hospitalizations due to RSV by 84.3% within 150 days post-treatment. Further evidence from the SMART Phase 3 study validated Clesrovimab’s efficacy and safety in both preterm and full-term infants, as well as high-risk populations, where it showed superior performance compared to existing standard preventive therapies. 9. Amlodipine Besylate/Indapamide/Telmisartan Amlodipine Besylate/Indapamide/Telmisartan, marketed as Widaplik, is a fixed-dose triple combination therapy developed by George Medicines Pty Ltd. It received its first FDA approval on June 5, 2025, for the treatment of hypertension. Widaplik is the first and currently only FDA-approved triple-combination product specifically designed for patients who may require multiple antihypertensive agents to achieve optimal blood pressure control. Widaplik combines three active components, each with a distinct antihypertensive mechanism: ·Amlodipine, a calcium channel blocker, relaxes vascular smooth muscle by inhibiting calcium influx into cardiac and arterial wall cells. ·Telmisartan, an angiotensin II receptor blocker (ARB), prevents vasoconstriction and reduces fluid retention by blocking angiotensin II. ·Indapamide, a thiazide-like diuretic, promotes the excretion of sodium and water, further lowering blood pressure. Approval was supported by two pivotal clinical studies: Study 1 enrolled 295 patients with systolic hypertension who were either treatment-naïve or on monotherapy. Following a 2-week placebo run-in, patients were randomized to receive different doses of Widaplik or placebo. At week 4, both Widaplik doses significantly reduced home-measured systolic blood pressure compared to placebo (P < 0.0001), with most of the antihypertensive effect observed within the first two weeks. Study 2 compared Widaplik to dual-component therapies. At week 12, Widaplik achieved superior reductions in home systolic blood pressure versus all dual-therapy arms (P < 0.0001). The effect was consistent across age, sex, and racial subgroups. In terms of safety, Widaplik was generally well tolerated. The most common adverse events were symptomatic hypotension and electrolyte imbalances such as hyponatremia and hypokalemia. Summary June 2025 marked the approval and launch of several milestone new drugs in the global pharmaceutical landscape, representing significant advances across multiple therapeutic areas. From targeted precision therapies like Taletrectinib and Garadacimab, to multimodal combination regimens like Widaplik, and passive immunization agents such as Clesrovimab and Genakumab, to next-generation vaccines like the quadrivalent influenza vaccine and the 13-valent pneumococcal conjugate vaccine, these innovative products exemplify the synergistic potential of biologics and small molecules. Together, they are not only enhancing treatment efficacy across various diseases but are also shaping the future of personalized, effective, and sustainable medicine. How to obtain the latest research advancements in the field of biopharmaceuticals? In the Synapse database, you can keep abreast of the latest research and development advances in drugs, targets, indications, organizations, etc., anywhere and anytime, on a daily or weekly basis. Click on the image below to embark on a brand new journey of drug discovery!

☝ 点击上方 一键预约 ☝   最新最热的医药健康新闻政策☝ ☝ 点击查看峰会活动议程 ☝ ☝ 7月15日，国家组织药品联合采购办公室发布通知，启动第11批国家组织药品集中采购相关药品信息填报工作，并公布拟纳入第11批集采的清单，共计55个品种。重磅！第十一批药品国采开始报量！（附产品清单）当天，国家医保局召开媒体通气会，介绍优化集采的措施。据了解，本次集采优化了品种遴选条件。55个品种如何而来？会上，国家组织药品联合采购办公室（以下简称国家组织药品联采办）主任郑颐作了详细解读。“按照要求，我办以2025年3月31日为时间节点，沿用第10批集采‘参比制剂和通过一致性评价仿制药企业数达到7家及以上’作为第11批集采的品种遴选条件。”郑颐介绍，品种信息来源包括三个方面：一是中国医药工业信息中心提供的国家药监局化学药品目录集（内含参比制剂和过评药品信息），二是国家药监局公开发布的仿制药参比制剂目录（内含参比制剂信息），三是米内数据库的一致性评价进度信息（内含过评药品信息）。三方面来源的数据互为补充，取并集汇总后满足遴选条件品种数有122个。在此基础上，国家组织药品联合采购办公室对拟纳入品种进行遴选，主要包括三个步骤。第一步：结合医保目录、市场规模等进行筛选郑颐介绍，第11批集采聚焦临床使用成熟、市场竞争充分的品种，更好发挥集采的规模效应，在满足遴选条件的基础上，结合既往品种遴选规则和集采政策优化要求，排除存在以下情形的品种：一是主要成分、给药途径和适应证相同但包含医保目录内品规和目录外品规的“跨医保目录”品种，区分为医保内、外分组采购，区分后不满足竞争格局的，不纳入。此种情形共排除了替米沙坦氨氯地平口服常释剂型、氨溴索吸入剂2个品种，以及复方电解质注射剂、二甲双胍恩格列净口服常释剂型等7个品种的部分品规。如替米沙坦氨氯地平口服常释剂型（总格局1+6，即参比制剂有1家企业，通过一致性评价有7家企业，下同），同属口服常释剂型的有2个品规，分别为替米沙坦氨氯地平片（1+4，医保）和替米沙坦氨氯地平片（Ⅱ）（0+4，自费），区分医保和自费性质后2个品规均未满足竞争格局，按此情形替米沙坦氨氯地平口服常释剂型不纳入。“此条遴选规则也是为了保障患者医保报销的公平性，使用同一集采品种的不同患者的报销属性相同。”郑颐说。二是协议期内的国家医保谈判药品、新进入医保目录首年的竞价药品不纳入，共排除奥美拉唑碳酸氢钠口服液体剂1个品种以及复方氨基酸注射剂、二甲双胍恩格列净口服常释剂型等3个品种的部分品规。参照最新版《国家基本医疗保险、工伤保险和生育保险药品目录（2024年）》，国家医保目录中谈判药品协议期内暂不纳入集采，竞价药品沿用既往规则在新进入医保目录首年暂不纳入集采，次年如符合条件则纳入集采。如奥美拉唑碳酸氢钠口服液体剂的“（Ⅱ）”品规在谈判协议期内，去除该品规后，其余品规竞争格局为“0+6”，不符合竞争格局条件，故该品种不纳入。二甲双胍恩格列净口服常释剂型的“（Ⅲ）”“（Ⅵ）”品规处于首年竞价药品，不纳入，去除该2品规后，其余品规仍满足竞争格局条件，保留。三是2024年采购金额小于1亿元的品种不纳入，共排除他氟前列素滴眼剂、林可霉素注射剂等24个品种。国家组织药品联采办与国家医保局价采中心、首都医科大学国家医疗保障研究院三方背对背测算各品种省级平台采购金额，2024年采购金额小于1亿元的品种不纳入。四是尚未启动一致性评价且新老批件并存的品种不纳入，共排除他克莫司软膏剂、利培酮口服液体剂等19个品种。目前药监部门主要针对口服固体制剂和注射剂开展一致性评价工作，对口服溶液剂、吸入剂、滴眼剂、外用制剂等其他剂型的一致性评价工作方案正在研究中。这类剂型药品中可能存在部分尚未开展一致性评价的老批件产品，以及部分近年来通过新注册分类获批的视同过评药品，考虑到国家组织集采的投标产品须通过或视同通过一致性评价，为保障竞争的公平性，这类药品不纳入。五是存在装置适配风险的药械组合产品暂不纳入，共排除腹膜透析液注射剂（含普通和低钙）1个品种。该药品属于药械组合产品，用于慢性肾功能衰竭透析。除药品本身外，需配合医疗器械装置使用，药品包装与装置之间的适配性可能影响患者用药安全。鉴于临床使用等风险，不纳入。排除上述情形的品种后，剩余75个品种。第二步：征求临床医学和药学专家意见郑颐介绍，按照国家集采工作流程，国家组织药品联采办于2025年5月13日在北京召开临床和药学专家咨询会，从临床使用和药学特性等角度听取专家意见，包括：品种是否适合纳入本次集采、同品种不同品规间是否可替代、品种是否存在临床使用其他风险等。结合临床专家意见，主要成分相同但使用装置、临床使用场景、作用时效等不完全相同的，区分为不同品种集采，不满足竞争格局的，不纳入。共排除复方氨基酸注射剂1个品种以及丙卡特罗吸入剂等7个品种的部分品规，同时也有复方电解质注射剂1个品种区分后有2个品规均符合格局，按2个品种纳入。如复方氨基酸注射剂包括15AA-Ⅱ、18AA-Ⅱ、18AA-Ⅶ、19AA-I、20AA等品规，临床专家提出不同数字代表所含氨基酸种类数和配方不同，临床使用场景有差异，需根据患者实际病情选择，不能相互替代，参比制剂也不同，应作为不同品种进行集采。区分后，各品规竞争格局均不满足条件，故未纳入。综合专家共识，剩余75个品种。第三步：根据相关部门及专家意见，进一步剔除存在相关风险的品种一是专利尚未到期且知识产权承诺企业数不满足遴选条件的品种暂不纳入。结合相关部门意见和企业知识产权自主承诺情况，剔除阿格列汀口服常释剂型、伏诺拉生口服常释剂型、沙库巴曲缬沙坦口服常释剂型、恩扎卢胺口服常释剂型、吲哚布芬口服常释剂型等有重要专利尚未到期且知识产权承诺企业数不满足遴选条件的5个品种。二是临床使用风险较高的品种不纳入。采纳相关部门和专家意见，剔除万古霉素、麦考酚钠、拉莫三嗪、碘普罗胺注射剂、甲氨蝶呤、曲普瑞林等14个临床使用风险较高的品种。这些药品是重点管理抗菌药物、窄治疗指数药物、容易发生严重不良反应的药物，以及辅助生殖技术相关药物等，这类药品对临床诊疗经验要求高、医师和患者用药习惯依从性强，为进一步保障集采结果平稳实施，暂不纳入本次集采。例如，碘普罗胺注射剂（造影剂）属于高警示药物，易发生过敏性休克等严重不良反应，阿糖胞苷注射剂、甲氨蝶呤注射剂（白血病用药）涉及鞘内注射，通过腰椎穿刺将药物直接注入蛛网膜下腔，可能引发脑膜炎、颅内感染等，严重时危及生命。另有中/长链脂肪乳（C6-24）1个品种，按照2025年版《中华人民共和国药典》其命名将与中/长链脂肪乳注射液C8-24、C8-24Ve合并，统一称为“中/长链脂肪乳注射液”。而C8-24Ve为第五批集采品种，将于近期进行接续采购。临床医生、药师反映，上述品种在临床上可相互替代，合并命名更有利于临床用药管理。因此，为平稳执行中选结果，中/长链脂肪乳（C6-24）注射液不再单独纳入第11批集采，与第五批集采品种中/长链脂肪乳（C8-24）、（C8-24Ve）注射液共同纳入接续采购。郑颐介绍，经过三个阶段筛选，最终有55个品种纳入第11批集采报量范围。(来源：中国卫生杂志 作者：吴少杰 ）有需要《第十一批药品国采最新竞争格局》（完整Excel版），请扫描下方二维码添加客服微信咨询，申请加入药闻康策高端会员群获取。药闻康策新媒体矩阵微信公众号点击下方  一键关注【免责声明】1.“药闻康策”部分文章信息来源于网络转载是出于传递更多信息之目的，并不意味着赞同其观点或证实其内容的真实性。如对内容有疑议，请及时与我司联系。2.“药闻康策”致力于提供合理、准确、完整的资讯信息，但不保证信息的合理性、准确性和完整性，且不对因信息的不合理、不准确或遗漏导致的任何损失或损害承担责任。3.“药闻康策”所有信息仅供参考，不做任何商业交易或医疗服务的根据，如自行使用“药闻康策”内容发生偏差，我司不承担任何责任，包括但不限于法律责任，赔偿责任。欢迎转发分享、点赞、点在看