Sichuan Clover Biopharmaceuticals, Inc

The malignant ascites pipeline possesses only two drugs in mid-stage developments to be approved in the near future. The major key players include Clover Biopharmaceuticals and Wuhan YZY Biopharma which hold the potential to create a significant positive shift in the malignant ascites market size. LAS VEGAS, April 29, 2024 /PRNewswire/ -- DelveInsight's Malignant Ascites Market Insights report includes a comprehensive understanding of current treatment practices, malignant ascites emerging drugs, market share of individual therapies, and current and forecasted market size from 2020 to 2034, segmented into 7MM [the United States, the EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan]. Key Takeaways from the Malignant Ascites Market Report According to DelveInsight's analysis, the market size for malignant ascites reached USD 1.9 billion in 2020 across the 7MM, which is anticipated to rise to USD 2.3 billion by 2034. In 2020, the total incident cases of malignant ascites-associated cancers were ~1.6 million in the 7MM. Leading malignant ascites companies such as LINDIS BIOTECH, WUHAN YZY BIOPHARMA CO., LTD., CLOVER BIOPHARMACEUTICALS, BINHUI BIOPHARMACEUTICAL, PHARMACYTE BIOTECH INC., and others are developing novel malignant ascites drugs that can be available in the malignant ascites market in the coming years. The promising malignant ascites therapies in the pipeline include CATUMAXOMAB, M 701, SCB-313, VAK, and CYPSCAPS PLUS IFOSFAMIDE, among others. Wuhan YZY Biopharma's M701 is the first and only EpCAM × CD3 BsAb that has entered into a Phase II clinical trial for the treatment of M701 globally. Even with the new therapies coming in the market, still the mainstay treatment for Malignant Ascites will remain chemotherapy over the years. Out of the novel treatments, the highest revenue is expected to be generated by CATUMAXOMAB with 10.54% of share of the total market in 2034, followed by KM-CART with 5.07% and OK-432 with 2.21% of market share, respectively. Discover which therapies are expected to grab the major malignant ascites market share @ Malignant Ascites Market Report Malignant Ascites Overview Malignant ascites is a pathological condition stemming from various primary abdominal and non-abdominal cancers. It stands as a significant source of illness, presenting numerous complexities and treatment obstacles. It serves as an indicator of peritoneal carcinomatosis, denoting the presence of cancerous cells within the peritoneal cavity. Carcinomatosis-causing tumors are frequently secondary malignancies affecting the peritoneal surface, such as those from ovarian, colorectal, pancreatic, and uterine origins; as well as extraperitoneal tumors originating from lymphoma, lung, and breast cancers, alongside smaller proportion of unidentified primary tumors. The origins of fluid accumulation within the abdomen are diverse and may include cirrhosis, congestive heart failure, nephrosis, pancreatitis, peritonitis, primary malignancies, or liver metastases. Differentiating between benign and malignant ascites solely through physical examination or radiographic methods is not feasible. Invasive procedures are required to distinguish between the two types. Ascitic fluid analysis through abdominal paracentesis can typically identify malignant causes of ascite production; however, laparoscopic tissue sampling might be necessary in certain cases. Malignant Ascites Epidemiology Segmentation The malignant ascites epidemiology section provides insights into the historical and current malignant ascites patient pool and forecasted trends for the 7MM. It helps recognize the causes of current and forecasted patient trends by exploring numerous studies and views of key opinion leaders. The malignant ascites market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into: Total Incident Cases of Ascites in Selected Indications (Ovarian, Colorectal, Gastric, and Others) Incident Cases of Malignant Ascites in Selected Indications Total Treated Cases of Malignant Ascites Malignant Ascites Treatment Market The available treatments for malignant ascites consist of various strategies designed to ease symptoms and enhance quality of life. These methods include draining fluids through paracentesis, using chemotherapy to combat cancer cells and lessen ascite formation, employing targeted therapy tailored to particular cancer types, opting for surgical procedures like tumor removal or shunt insertion, and incorporating supportive measures such as diuretics and nutritional assistance. The selection of treatment is determined by factors such as the specific cancer type and the severity of symptoms, with the main objective being the management of symptoms and the improvement of overall well-being. Malignant ascite treatments aimed at causing a reduction in malignant ascites mainly consist of systemic chemotherapy, targeted therapy, or surgical procedures designed to decrease or remove the cancerous tumors accountable for the development of ascites. These methods focus on the fundamental cause of ascites by dealing with the underlying cancer, intending to slow down the advancement of the disease and enhance the outcomes for the patient. With just two accepted treatments, OK-432 and KM-CART, available in Japan, many patients are left with only palliative care, which often falls short of addressing their needs. Various methods exist to relieve symptoms linked with malignant ascites. However, due to a lack of understanding of ascites' natural progression, there is limited data on these approaches and their impact on quality of life. Assessing the effectiveness of current treatments is challenging. Common traditional methods for handling malignant ascites encompass sodium-restricted diets, diuretic treatment, repeated paracentesis, and peritoneovenous shunting. To know more about malignant ascites treatment guidelines, visit @ Malignant Ascites Management Malignant Ascites Pipeline Therapies and Key Companies CATUMAXOMAB: LINDIS BIOTECH M 701: WUHAN YZY BIOPHARMA CO., LTD. SCB-313: CLOVER BIOPHARMACEUTICALS VAK: BINHUI BIOPHARMACEUTICAL CYPSCAPS PLUS IFOSFAMIDE: PHARMACYTE BIOTECH INC. Learn more about the FDA-approved drugs for malignant ascites @ Drugs for Malignant Ascites Treatment Malignant Ascites Market Dynamics The dynamics of the malignant ascites market are expected to change in the coming years. SCB-313 utilizes distinctive, patented protein trimerization technology to precisely target and activate the triple-dependent mechanism of tumor cell apoptosis, fostering collaboration among oncologists, surgeons, researchers, and other healthcare professionals to develop effective management strategies, identification of novel therapeutic targets through advanced molecular analyses, and an emphasis on patient-centered care and improved symptom management to enhance the overall quality of life for patients with malignant ascites. Furthermore, many potential therapies are being investigated for the treatment of malignant ascites, and it is safe to predict that the treatment space will significantly impact the malignant ascites market during the forecast period. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the malignant ascites market in the 7MM. However several factors may impede the growth of the malignant ascites market. Tackling malignant ascites poses ongoing difficulties in clinical management, with the current focus primarily on alleviating symptoms rather than achieving a definitive cure, due to the absence of universally accepted treatment protocols stemming from limited evidence and patient heterogeneity; consequently, malignant ascites also presents research obstacles, with only a few attempts made to develop medications for the condition, and the potential hindrance of access to emerging therapies once approved by the availability of off-label therapies. Moreover, malignant ascites treatment poses a significant economic burden and disrupts patients' overall well-being and QOL. Furthermore, the malignant ascites market growth may be offset by failures and discontinuation of emerging therapies, unaffordable pricing, market access and reimbursement issues, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the malignant ascites market growth. Scope of the Malignant Ascites Market Report Therapeutic Assessment: Malignant Ascites current marketed and emerging therapies Malignant Ascites Market Dynamics: Key Market Forecast Assumptions of Emerging Malignant Ascites Drugs and Market Outlook Competitive Intelligence Analysis: SWOT analysis and Market entry strategies Unmet Needs, KOL's views, Analyst's views, Malignant Ascites Market Access and Reimbursement Discover more about malignant ascites drugs in development @ Malignant Ascites Clinical Trials Table of Contents Related Reports Malignant Ascites Pipeline Malignant Ascites Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key malignant ascites companies, including Clover Biopharmaceuticals, YZY Biopharma, Sorrento Therapeutics, Inc., Simcere, PharmaCyte Biotech, Linton Pharm, among others. Malignant Ascites Epidemiology Forecast Malignant Ascites Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted malignant ascites epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan. Ascites Market Ascites Market Insights, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key ascites companies, including Grifols Therapeutics LLC, Sanofi, Regeneron Pharmaceuticals, Sequana Medical N.V, Protgen Ltd, Healthgen Biotechnology Corp, Sichuan Clover Biopharmaceuticals Inc, Movetis, BioVie Inc., Ocelot Bio Inc, Novartis, among others. Ascites Pipeline Ascites Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key ascites companies, including Grifols Therapeutics LLC, Sanofi, Regeneron Pharmaceuticals, Sequana Medical N.V, Protgen Ltd, Healthgen Biotechnology Corp, Sichuan Clover Biopharmaceuticals Inc, Movetis, BioVie Inc., Ocelot Bio Inc, Novartis, among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve . Contact Us Shruti Thakur [email protected] +14699457679 Logo: SOURCE DelveInsight Business Research, LLP

-- Clover's seasonal influenza vaccine BLA submission has been completed in Brazil, boosting Clover's global presence -- SHANGHAI, Nov. 6, 2023 /PRNewswire/ -- Clover Biopharmaceuticals, Ltd. (Clover; HKEX: 02197), a global commercial-stage biotechnology company committed to unleashing the power of innovative vaccines to save lives and improve health around the world, today announced the company completes the Biologic License Application (BLA) submission for its seasonal influenza vaccine (AdimFlu-S) to Brazilian Health Regulatory Agency (Agência Nacional de Vigilância Sanitária, or ANVISA). Upon approval, Clover will work with its local partner to commercialize the product in Brazil. "The BLA submission of AdimFlu-S in Brazil is another step towards our goal of becoming a global leader in the respiratory vaccine space and builds upon Clover's prior experience enrolling over 10,000 people in clinical trials across Brazil and South America," said Joshua Liang, Chief Executive Officer and Executive Director of Clover, "By leveraging our unique globalization capabilities, we will continue expanding to other countries and regions to diversify our sales and maximize our impact on public health." If approved in Brazil, Clover's seasonal influenza vaccine would have access to the Southern Hemisphere market, enabling annual sales in the first half of the year to supplement sales in the second half of the year in Northern Hemisphere markets such as China, while also better utilizing Adimmune's production capacity year-round. Brazil is an important vaccine market strategically, as the country has the world's second largest seasonal influenza vaccine market, with total local market size expected to surpass US$1 billion over the next 5 years, according to Globaldata. About Clover Clover Biopharmaceuticals is a global commercial-stage biotechnology company committed to unleashing the power of innovative vaccines to save lives and improve health around the world. With integrated research and development, manufacturing and commercial capabilities as well as strong partnerships with organizations globally, Clover has a diverse pipeline of candidates that have the potential to meaningfully reduce the burden of vaccine-preventable diseases—and to make more diseases preventable.  Clover Forward-looking Statements This press release contains certain forward-looking statements and information relating to us and our subsidiaries that are based on the beliefs of our management as well as assumptions made by and information currently available to our management. When used, the words "aim," "anticipate," "believe," "could," "estimate," "expect," "going forward," "intend," "may," "might," "ought to," "plan," "potential," "predict," "project," "seek," "should," "will," "would" and the negative of these words and other similar expressions, as they relate to us or our management, are intended to identify forward-looking statements. Forward-looking statements are based on our current expectations and assumptions regarding our business, the economy and other future conditions. We give no assurance that these expectations and assumptions will prove to have been correct. Because forward-looking statements relate to the future, they are participant to inherent uncertainties, risks and changes in circumstances that are difficult to predict. Our results may differ materially from those contemplated by the forward-looking statements. They are neither statements of historical fact nor guarantees or assurances of future performance. We caution you therefore against placing undue reliance on any of these forward-looking statements. Any forward-looking statement made by us in this document speaks only as of the date on which it is made. Factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. Participant to the requirements of applicable laws, rules and regulations, we undertake no obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise. All forward-looking statements contained in this document are qualified by reference to this cautionary statement. Clover Biopharmaceuticals: Corporate Communication: Lola Cao [email protected] Investor Relations: Elaine Qiu [email protected] SOURCE Clover Biopharma

上海 2023年6月16日 /美通社/ -- 云顶新耀（HKEX 1952.HK）是一家专注于创新药及疫苗开发、制造和商业化的生物制药公司，今日宣布任命Mike Berry博士为首席技术官，该任命立即生效。Berry博士在将项目从临床前开发阶段推进到商业化阶段方面拥有超过30年的行业经验。 Berry博士在生物制药开发、规模扩大和生产等方面拥有丰富的经验，他还精通良好生产规范（GMP）和化学制造与控制（CMC）等方面的专业知识。作为首席技术官，Berry博士将负责云顶新耀的所有CMC活动，同时负责公司位于浙江嘉善的产业化基地的运营和管理。该先进的生产基地将全面符合国际和中国GMP要求，每年可生产7亿剂次mRNA疫苗。 云顶新耀首席执行官罗永庆表示："Berry博士在CMC和生产运营方面拥有深厚的专长和丰富的经验，这将帮助云顶新耀完善其战略性全产业链布局。他的加入将增强我们的自我研发和制造能力，推动云顶新耀从临床阶段的生物技术公司向综合性生物制药公司的转变。" Berry博士表示："很高兴能够加入云顶新耀助推其领先的药物开发，以满足大中华区和其他亚洲地区尚未满足的医疗需求。我期待利用我的专业知识，通过规模化、高效的生产流程，开发并生产出更多的创新药物和疫苗。" 在加入云顶新耀之前，Berry博士曾担任三叶草生物制药有限公司的全球首席技术运营官，负责三叶草全球原料药和药物制剂的开发和生产。在此之前，Berry博士曾在多家美国和国际生物技术公司担任领导职位，其中包括Dynavax Technologies Corp.和Novartis Diagnostics，还曾在BioTechLogic, Inc.担任CMC顾问。他在大分子和小分子原料药和药物产品开发、制造、测试以及药品供应链方面拥有丰富的经验。 Berry博士拥有加拿大曼尼托巴大学微生物学博士学位。 关于云顶新耀 云顶新耀是一家专注于创新药和疫苗开发、制造及商业化的生物制药公司，致力于满足亚洲市场尚未满足的医疗需求。云顶新耀的管理团队在中国及全球领先制药企业从事过高质量临床开发、药政事务、化学制造与控制（CMC）、业务发展和运营，拥有深厚的专长和丰富的经验。云顶新耀已打造多款有潜力成为全球同类首创或者同类最佳的药物组合，其中大部分已经处于临床试验后期阶段。公司的治疗领域包括肾科疾病、感染性和传染性疾病、自身免疫性疾病。有关更多信息，请访问公司网站： www.everestmedicines.com 。 前瞻性声明： 本新闻稿所发布的信息中可能会包含某些前瞻性表述，乃基于本公司或管理层在做出表述时对公司业务运营情况及财务状况的现有看法、相信、和现有预期，可能会使用"将"、"预期"、"预测"、"期望"、"打算"、"计划"、"相信"、"预估"、"确信"及其他类似词语进行表述。这些前瞻性表述并非对未来业绩的保证，会受到风险、不确性及其他因素的影响，有些乃超出本公司的控制范围，难以预计。因此，受我们的业务、竞争环境、政治、经济、法律和社会情况的未来变化及发展等各种因素及假设的影响，实际结果可能会与前瞻性表述所含资料有较大差别。本公司及各附属公司、各位董事、管理人员、顾问及代理未曾且概不承担更新该稿件所载前瞻性表述以反映在本新闻稿发布日后最新信息、未来项目或情形的任何义务，除非法律要求。