Objective: Without changing the preparation process, use several different packaging materials and packaging forms to package norfloxacin capsules, and select the packaging material with the best sample data (dissolution test) for production Solve the problem that the dissolution rate of the product does not meet the quality standard during the storage period. Different packaging materials and packaging forms for testing were selected, and the most suitable packaging materials and process parameters were screened out. (1) Through the comparison of the capsule detection conditions of various manufacturers, it could be seen that the dissolution data of the packaging form with a back-sealed bag was better. (2) Capsule shells from different manufacturers were selected for sub-packaging test, and suitable capsule shells for production were selected. (3) Different aluminum-plastic packaging forms were chosen for packaging, and the appropriate packaging form could be seen according to the test data. The choice of capsule shell and packaging materials can solve the problem of unqualified dissolution of norfloxacin capsules during the storage period.