Additional funding awarded following successful drug candidate nomination USD 7.3 million to support progression of antibiotic BAL2420 (LptA inhibitor) towards first-in-human clinical studies December 23, 2024 Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today that it was awarded an additional USD 7.3 million from CARB-X (Combating Antibiotic-Resista

Dec. 18, 2024 -- Tessera Therapeutics, a biotechnology company pioneering a new approach to genome engineering through the development of its Gene Writing™ and delivery platforms, announced today that it has entered into an agreement with the Bill & Melinda Gates Foundation to jointly fund the company’s in vivo program for sickle cell disease (SCD). The funding includes an initial investment, with potential total investment of up to $50 million, from the Gates Foundation intended to support the

Dec. 02, 2024 -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company, today announced a $10 million equity financing with strategic shareholder JuvVentures (UK) Limited. The transaction provides Serina with funding to continue advancing SER-252 (POZ-apomorphine), enabled by its proprietary POZ Platform™ drug optimization technology, into a Phase 1 clinical trial in advanced Parkinson's disease patients in the second half of 2025. Under the terms o

Financing led by Frazier Life Sciences with participation from new investors including Vivo Capital, Janus Henderson Investors, Deep Track Capital, Paradigm BioCapital Advisors and Columbia Threadneedle Nov. 26, 2024 -- 35Pharma, a clinical-stage biopharmaceutical company developing TGF-beta superfamily therapeutics, today announced the closing of an oversubscribed $53 million Series C financing. The company plans to use the proceeds to advance its pipeline of Activin and GDF inhibitors, HS135

Klothea Bio Secures Funding from Longevitytech.fund as a lead investor to Pioneer Breakthrough Treatments for Metabolic Syndrome and several Aging-Associated DiseasesMIAMI, Nov. 25, 2024 (GLOBE NEWSWIRE) -- Advantage Therapeutics Inc., a leader in developing therapies targeting age-related diseases, announced today the formation of its new subsidiary, Klothea Bio, Inc., which will focus exclusively on the research and development of Klotho-based therapies to prevent and treat various age-assoc

- Phase 1 study and Investigator Initiated Trial evaluating KL003 for patients with beta thalassemia demonstrated an encouraging efficacy signal and favorable safety profile – - Manufacturing costs for KL003 are significantly reduced compared to currently approved gene therapies - - Phase 2 pivotal study for KL003 in beta thalassemia expected to start in 2025 - Nov. 25, 2024 -- Kanglin Biotechnology (Hangzhou) Co., Ltd, an innovative biotech company developing the next generation of gene thera

Nov. 21, 2024 -- DANNCE.AI raised $2.6 million in pre-seed funding led by LDV Capital, following initial investment from Glasswing Ventures, with participation from The Leo Lion Company, Duke Capital Partners, and Merck Digital Sciences Studio. DANNCE.AI is bringing to market DANNCE, a novel phenotyping platform to digitize the clinical assessments used by doctors and therapeutic developers to quantify movement. DANNCE is a new approach to the clinical exam that ingests videos of patients and a

近日，作为放射性药物领域的创新药企杭州赛核生物技术有限公司（简称“赛核生物”）宣布完成天使轮融资。据悉，本轮融资由冷杉溪资本独家投资，融资规模达数千万元。 癌症是人类健康的重大威胁，是世界和我国居民最主要的死亡原因之一。靶向阿尔法粒子放疗，通过靶向分子将阿尔法粒子同位素精准的递送到癌症组织进行高强度局部内放射治疗，具有强效、特异的优势，是当今国际上癌症治疗的最前沿领域和投资热点。仅2024年至今，阿斯利康，百时美施贵宝等多家大型跨国药企便投入上百亿美元进军靶向阿尔法粒子放疗领域。日本政府已经将靶向阿尔法粒子放疗定为未来癌症治疗的国家战略。我国中央多部委也先后出台了《医用同位素中长期发展规划（2021-2035）》和《核技术应用产业高质量发展三年行动方案（2024-2026）》，大力促进我国核药事业的发展。业内预计2021年至2025年期间，中国核素显像诊断和治疗用放射性药物市场规模将达到32.4%的年复合增长率。预计2025年市场规模将达到93亿元人民币，2030年市场规模将进一步扩大至260亿元人民币。 赛核生物致力于通过研发具有完全自主知识产权的原创核心技术成为国际领先的核药创

11月20日，百明信康宣布完成新一轮数亿元融资。本轮融资由人保资本股权、清松资本、某知名产业投资机构等多家知名机构和产业投资方共同投资。百明信康成立于2018年，致力于研发针对过敏性疾病及自身免疫疾病的新一代特异性免疫疗法。 根据百明信康新闻稿介绍，该公司在欧洲拥有产、研、销一体化的全资子公司，拥有数十款商业化产品。百明信康正积极拓展全球市场，并推动欧洲已上市创新过敏免疫治疗产品在中国的临床开发及商业化。同时其快速构建了基于新技术平台的过敏和自身免疫性疾病适应症的研发管线，其中草花粉过敏、格雷夫斯症等数个管线已在全球不同国家分别进入临床2期、3期研究阶段。 百明信康主要商业化产品包括天然提取变应原SCIT、SLIT（喷剂）过敏治疗产品；分子变应原过敏治疗产品；类变应原过敏治疗产品以及过敏诊断产品。此外，根据百明信康官网介绍，该公司正在开发基于两大技术平台的各种免疫疗法，利用PCFiT （重组肽载体融合蛋白）技术治疗过敏性鼻炎、过敏性结膜炎和过敏性哮喘；利用 Apitopes （可诱导免疫耐受多肽）技术治疗多发性硬化、格雷夫斯病、葡萄膜炎、血友病VIII因子抑制物，以及心肌炎和类风湿

11月18日，领泰生物刚刚宣布完成超亿元A轮融资。本轮融资由北京龙磐创投领投，天瑞丰年投资跟投，老股东张科领弋创投继续追加投资。根据新闻稿，此次募集资金将主要用于加速领泰生物首个管线IRAK4降解剂LT-002的1期及后续临床研究，其他自免和肿瘤管线的临床前开发等。 领泰生物创立于2019年，该公司主要以靶向蛋白降解（TPD）药物技术为核心开发小分子创新药，聚焦于自身免疫和肿瘤等疾病领域。 领泰生物的IRAK4降解剂LT-002（一款靶向蛋白降解嵌合体，PROTAC）在今年6月份启动首次人体试验，4个月内已经完成65例健康志愿者单次或多次给药观察。目前未揭盲数据显示，LT-002在健康志愿者中具有良好的安全性和耐受性，在靶组织皮肤中呈现较高的蓄积，对于PMBC以及皮肤中IRAK4蛋白均具有优异的降解作用，而且呈现明显的剂量依赖性。同时，对于多个促炎细胞因子的释放也有显著的抑制作用。 IRAK4（白细胞介素-1受体相关激酶4）是人体IRAK激酶家族同工酶之一，在蛋白质磷酸化以及细胞信号转导中发挥了重要作用。它接收来自上游toll样受体家族（TLRs）以及白细胞介素-1型受体家族（IL