Sodium Hyaluronate

精彩内容 6月6日是全国爱眼日。米内网数据显示，2023年中国公立医疗机构终端眼科用药销售额超过140亿元，TOP20产品中，“一哥”易主，两大独家品种涨超120%；目前22个眼科用药已有企业过评/视同过评，齐鲁领跑过评榜；5个品种已纳入国采，4个品种备战第十批集采。 超140亿！眼科用药市场创新高 近年来，随着人口老龄化进程加快、生活方式变化、电子产品的普及等，眼部疾病的发病率及用药需求均在不断提升。 米内网数据显示，2023年中国城市公立医院、县级公立医院、城市社区中心以及乡镇卫生院（简称中国公立医疗机构）终端眼科用药（化学药+生物药）销售额超过140亿元，同比增长约18%，其中化学药占比约65%，生物药占比约35%。 近年来中国公立医疗机构终端眼科用药销售情况（单位：万元）来源：米内网中国公立医疗机构药品终端竞争格局 从2023年眼科用药厂家排名看，诺华、康弘药业、参天制药、沈阳兴齐眼药、拜耳位列前五，且销售额增速均超过10%，其中诺华、康弘药业市场份额均超过10%，沈阳兴齐眼药销售额增速约达36%，较2022年提升1个位次。 2023年中国公立医疗机构终端眼科用药TOP5集团来源：米内网中国公立医疗机构药品终端竞争格局 2023年眼科用药TOP20产品中，康柏西普眼用注射液、雷珠单抗注射液、阿柏西普眼内注射溶液3款生物药位列前三，且销售额均超过10亿元。其中，康柏西普眼用注射液大涨30%，顶替雷珠单抗注射液拿下“销冠”宝座。 2023年中国公立医疗机构终端眼科用药TOP20产品注：标*为独家品种（含独家剂型）来源：米内网综合数据库 从销售额增速看，16个产品涨逾10%，沈阳兴齐眼药的环孢素滴眼液(Ⅱ)、珠海亿胜生物的牛碱性成纤维细胞生长因子滴眼液2款独家产品均涨超120%，其中环孢素滴眼液(Ⅱ)较2022年提升5个位次，牛碱性成纤维细胞生长因子滴眼液首次上榜TOP20产品。 2023年眼科用药TOP20品牌中，康弘药业的康柏西普眼用注射液排在首位；诺华有4个品牌上榜，且销售额均呈正增长，其中雷珠单抗注射液排位第二；参天制药有3个品牌上榜，其中玻璃酸钠滴眼液、地夸磷索钠滴眼液均涨超10%；珠海亿胜生物有2个品牌上榜，其中牛碱性成纤维细胞生长因子滴眼液涨超130%。 齐鲁领跑过评榜！5个品种已纳入国采 米内网数据显示，截至6月5日，有22个眼科用药（22个通用名药品）已有企业过评/视同过评，涉及超60家药企（以集团计）。 从品种过评情况看，5个眼科用药过评企业数（以企业名计）达10家及以上，且均已被纳入国采，其中盐酸莫西沙星滴眼液以34家企业成为最“抢手”品种，玻璃酸钠滴眼液以26家企业紧接其后，左氧氟沙星滴眼液以18家企业排位第三。 过评企业数超过10家的眼科用药 从企业过评情况看（以集团计），齐鲁制药领跑，过评品种数达8个；成都普什制药、沈阳兴齐眼药以6个品种并列第二，扬子江药业、南京恒道医药、远大医药、中山万汉制药、众生药业过评品种数均达5个。 已过评眼科用药品种数达5个及以上的集团 目前纳入国采的眼科用药仅有5个，且均为滴眼剂，包括第三批集采的左氧氟沙星滴眼液，第四批集采的盐酸奥洛他定滴眼液及玻璃酸钠滴眼液，第五批集采的盐酸莫西沙星滴眼液，第九批集采的地夸磷索钠滴眼液。 已纳入国采的眼科用药注：不含续约中选来源：米内网一致性评价进度数据库 左氧氟沙星滴眼液、盐酸奥洛他定滴眼液、玻璃酸钠滴眼液等品种在集采执行后，销售额连续多年下跌，2023年均迎来止跌回升。其中，玻璃酸钠滴眼液在中国公立医疗机构终端的销售峰值超过12亿元。 近年来中国公立医疗机构终端玻璃酸钠滴眼液销售情况（单位：万元）来源：米内网中国公立医疗机构药品终端竞争格局 6亿大品种在列！4个滴眼剂备战第十批集采 除去已纳入国家集采的品种，目前眼科用药还有4个品种满足集采门槛，符合申报资格企业数达5家及以上，均为滴眼剂。 满足5家及以上的条件且暂未纳入集采的眼科用药注：低于1亿元用*代表来源：米内网综合数据库 4个品种2023年在中国公立医疗机构终端销售规模合计超过10亿元，普拉洛芬滴眼液以6亿元领跑。 普拉洛芬属于非甾体抗炎药，其眼用制剂适用于外眼及眼前节炎症的对症治疗（眼睑炎、结膜炎、角膜炎、巩膜炎、浅层巩膜炎、虹膜睫状体炎、术后炎症）。米内网数据显示，2023年中国公立医疗机构终端普拉洛芬滴眼液销售额超过6亿元，同比增长约21%。 近年来中国公立医疗机构终端普拉洛芬滴眼液销售情况（单位：万元）来源：米内网中国公立医疗机构药品终端竞争格局 从2023年普拉洛芬滴眼液厂家格局看，原研厂家日本千寿制药主导市场，市场份额超过50%；山东海山药业以约39%的市场份额紧接其后，广东众生药业以约6%的市场份额排位第三。 2023年中国公立医疗机构终端普拉洛芬滴眼液厂家竞争格局来源：米内网中国公立医疗机构药品终端竞争格局 从过评企业来看，齐鲁制药涉及的过评品种数量达3个，其中公司在普拉洛芬滴眼液、酒石酸溴莫尼定滴眼液所占市场份额较低；天津医药、武汉先路医药过评品种数量均达2个，且均为“光脚”品种（指公司占比为0或较低）。 资料来源：米内网数据库等注：米内网《中国公立医疗机构药品终端竞争格局》，统计范围是：中国城市公立医院、县级公立医院、城市社区中心以及乡镇卫生院，不含民营医院、私人诊所、村卫生室；上述销售额以产品在终端的平均零售价计算。数据统计截至6月5日，如有疏漏，欢迎指正！ 本文为原创稿件，转载请注明来源和作者，否则将追究侵权责任。投稿及报料请发邮件到872470254@qq.com稿件要求详询米内微信首页菜单栏商务及内容合作可联系QQ：412539092 【分享、点赞、在看】点一点不失联哦

15 ePosters and In-Person Presentations Will Include Clinical Data on Blink™ NutriTears® Supplement for Dry Eyes, Blink® Triple Care Lubricating Eye Drops and MIEBO® (Perfluorohexyloctane Ophthalmic Solution) VAUGHAN, Ontario--(BUSINESS WIRE)-- Bausch + Lomb Corporation (NYSE/TSX: BLCO), a leading global eye health company dedicated to helping people see better to live better, today announced the presentation of 12 ePosters during the American Optometric Association (AOA) Optometry’s Meeting ePoster Session, taking place virtually May 29-30, 2024. The company will also have three live presentations and host nine education events during the in-person meeting, taking place in Nashville June 19-22, 2024. The OnDemand ePosters will feature new data on the early adoption of MIEBO and real-world patient experiences with Bausch + Lomb INFUSE® Multifocal silicone hydrogel daily disposable contact lenses. An evaluation of the performance of Biotrue® Hydration Plus Multi-Purpose Solution among two different patient demographics – soft contact lens wearers who are also frequent gamers and users planning to stop wearing lenses due to discomfort – will also be highlighted. The live, in-person presentations will include clinical data evaluating Blink NutriTears clinically proven nutritional supplement for dry eyes*, which was selected by AOA as one of the top five Optometry’s Meeting abstracts. Two other presentations will showcase clinical evaluation data for Blink Triple Care Lubricating Eye Drops, the first and only over-the-counter eye drop with both hyaluronate and a nano-emulsion lipid in the unique formula. The complete list of scientific ePosters and live presentations, as well as details for the featured education events, is as follows: e-Poster Presentations “A Multi-country Assessment of Satisfaction with a Spherical Silicone Hydrogel Daily Disposable Contact Lens Among New Contact Lens Wearers and Their Eyecare Professionals.” Reindel et al. “Comparison of Clinical Studies from the US and India of a Multi-Ingredient Oral Supplement.” Gioia et al. “Early Adoption and Utilization of Perfluorohexyloctane for Dry Eye Disease.” Alexander et al. “Evaluation of the Efficacy of a Novel Preservative-Free Formulation of Brimonidine Tartrate Ophthalmic Solution.” Evans et al. “Evaluation of the Safety of a Novel Preservative-Free Formulation of Brimonidine Tartrate Ophthalmic Solution.” Evans et al. “Frequent Gamers Tag a Novel Contact Lens Solution with High Satisfaction” Shahidi et al. “Improvement in Non-Invasive Tear Break-Up Time after Instillation of One Drop of Brimonidine Tartrate 0.025%.” Moore et al. “Ocular Vasoconstrictors: Does Mechanism of Action Make a Difference?” Moore et al. “On the Verge of Dropout: An In-Home Use Test of a Novel Contact Lens Solution Among Planned Replacement Contact Lens Wearers.” Shahidi et al. “Patient Performance Assessment with Multifocal Toric Silicone Hydrogel Contact Lenses.” Rah et al. “Patient-reported Instillation Comfort and Eyedrop Acceptability of Perfluorohexyloctane Ophthalmic Solution in Pivotal Clinical Studies.” Cunningham et al. “Real-world Evaluation of a Daily Disposable Silicone Hydrogel Multifocal Contact Lens.” Rah et al. Live Presentations “Clinical Evaluation of a Novel Lipid-Containing Eye Drop.” Coats et al. “Clinical Evaluation of a Multi-Ingredient Oral Supplement on Dry Eye Symptoms and Tear Volume.” Gioia et al. “Comparison of a Novel Lipid Nano-Emulsion Eye Drop with an Existing Lubricating Eye Drop.” Coats et al. Featured Education Events Wednesday, June 19 “Showcasing Inflammation and IOP Control with Bausch + Lomb” 6:30 p.m. CDT at The Palm (140 5th Avenue South, Nashville, Tenn.) Nora Lee Cothran, OD, FAAO, and Walter Whitley, OD, FAAO, will discuss the benefits of using LOTEMAX® SM (loteprednol etabonate ophthalmic gel), 0.38%, and VYZULTA® (latanoprostene bunod ophthalmic solution), 0.024%. Register in advance. Thursday, June 20 “Showcasing Inflammation and IOP Control with Bausch + Lomb” 8:00-9:00 a.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; room #104AB) Richard Madonna, OD, and Justin Schweitzer, OD, will discuss the benefits of using LOTEMAX SM (loteprednol etabonate ophthalmic gel), 0.38%, and VYZULTA (latanoprostene bunod ophthalmic solution), 0.024%. “NEW Breakthrough Supplement for Dry Eyes from Bausch + Lomb: Blink NutriTears” 12:00-1:00 p.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; room #104AB) Selina McGee, OD, FAAO, and Julie Poteet, OD, will lead a conversation on the new Blink NutriTears, a breakthrough, nutritional daily supplement for dry eyes. “Current Thinking in Dry Eye Disease: Contemporary Perspectives on a Complex Condition” 6:30-8:30 p.m. CDT at Morton’s Steakhouse (618 Church Street, Nashville, Tenn.) Learn about MIEBO, the first and only prescription eye drop that directly targets tear evaporation, as well as XIIDRA® (lifitegrast ophthalmic solution), 5%, the only nonsteroid anti-inflammatory prescription eye drop that can start to deliver dry eye symptom relief in just two weeks.1-2 Register in advance. “A NightCap in Nashville with Blink NutriTears” 8:00-10:30 p.m. (presentation at 9:00 p.m. CDT) at The Bell Tower (400th Ave. S, Nashville, Tenn.) Join Cecelia Koetting, OD, FAAO, to lean about Blink NutriTears clinically proven nutritional supplement for dry eyes. Friday, June 21 “Rethinking Dry Eye Disease: A Contemporary Approach to a Complex Condition” 8:00-9:00 a.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; room #104AB) Cecelia Koetting, OD, FAAO, and Nathan Lighthizer, OD, FAAO, will discuss the benefits of and differences between MIEBO and XIIDRA. “The Science of Eye Beauty with LUMIFY EYE ILLUMINATIONS™” 12:40-1:00 p.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; Exhibit Hall, Eye Talks Stage) Join Selina McGee, OD, FAAO, to learn about LUMIFY EYE ILLUMINATIONS, a clinically proven specialty eye care line. Saturday, June 22 “A Family of Eye Care Products with Innovations for Every Stage of Life” 9:00-10:00 a.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; room #104AB) Selina McGee, OD, FAAO, Mitch Ibach, OD, FAAO, and John Womack, OD, will share practical patient cases using products from across the Bausch + Lomb consumer, vision care and pharmaceutical portfolios. “The Puzzle of Dry Eye: Targeted Approaches to a Multifactorial Condition” 12:00-1:00 p.m. CDT at the Music City Center (201 Rep. John Lewis Way S, Nashville, Tenn.; room #104AB) Learn about the complex dry eye puzzle, Blink NutriTears, as well as MIEBO and XIIDRA. AOA’s Celebration of Optometry Event Additionally, Bausch + Lomb is the title sponsor of AOA’s Celebration of Optometry event, taking place at FGL House (120 3rd Ave South, Nashville, Tenn.) at 7 p.m. CDT on Friday, June 21. During the event, attendees will have the opportunity to learn about Bausch + Lomb’s latest innovations, including Bausch + Lomb INFUSE® for Astigmatism and Blink NutriTears. Important Safety Information for MIEBO INDICATION MIEBO (perfluorohexyloctane ophthalmic solution) is used to treat the signs and symptoms of dry eye disease. IMPORTANT SAFETY INFORMATION Patients should remove contact lenses before using MIEBO and wait for at least 30 minutes before reinserting. It is important for patients to use MIEBO exactly as prescribed. It is not known if MIEBO is safe and effective in children under the age of 18. The most common eye side effect seen in studies was blurred vision (1% to 3 % of patients reported blurred vision and eye redness). You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088. Click here for full Prescribing Information for MIEBO. WHAT IS XIIDRA? XIIDRA (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease. IMPORTANT SAFETY INFORMATION Do not use XIIDRA if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction. The most common side effects of XIIDRA include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation. To help avoid eye injury or contamination of the solution, do not touch the container tip to your eye or any surface. If you wear contact lenses, remove them before using XIIDRA and wait for at least 15 minutes before placing them back in your eyes. It is not known if XIIDRA is safe and effective in children under 17 years of age. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088. Click here for full Prescribing Information for XIIDRA. Important Safety Information for LOTEMAX SM INDICATION LOTEMAX SM (loteprednol etabonate ophthalmic gel) 0.38% is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular surgery. IMPORTANT SAFETY INFORMATION LOTEMAX SM, as with other ophthalmic corticosteroids, is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures. Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. Steroids should be used with caution in the presence of glaucoma. If LOTEMAX SM is used for 10 days or longer, IOP should be monitored. Use of corticosteroids may result in posterior subcapsular cataract formation. The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. In those with diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnification such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. In acute purulent conditions, steroids may mask infection or enhance existing infections. Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex). Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use. Fungal cultures should be taken when appropriate. Contact lenses should not be worn when the eyes are inflamed. There were no treatment-emergent adverse drug reactions that occurred in more than 1% of subjects in the three times daily group compared to vehicle. Click here for full Prescribing Information for LOTEMAX SM. Important Safety Information for VYZULTA INDICATION VYZULTA (latanoprostene bunod ophthalmic solution) 0.024% is indicated for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. IMPORTANT SAFETY INFORMATION Increased pigmentation of the iris and periorbital tissue (eyelid) can occur. Iris pigmentation is likely to be permanent. Gradual changes to eyelashes, including increased length, increased thickness, and number of eyelashes, may occur. These changes are usually reversible upon treatment discontinuation. Use with caution in patients with a history of intraocular inflammation (iritis/uveitis). VYZULTA should generally not be used in patients with active intraocular inflammation. Macular edema, including cystoid macular edema, has been reported during treatment with prostaglandin analogs. Use with caution in aphakic patients, in pseudophakic patients with a torn posterior lens capsule, or in patients with known risk factors for macular edema. There have been reports of bacterial keratitis associated with the use of multiple-dose containers of topical ophthalmic products that were inadvertently contaminated by patients. Contact lenses should be removed prior to the administration of VYZULTA and may be reinserted 15 minutes after administration. Most common ocular adverse reactions with incidence ≥2% are conjunctival hyperemia (6%), eye irritation (4%), eye pain (3%), and instillation site pain (2%). Please click here for full Prescribing Information. Patients are encouraged to report negative side effects of these prescription drugs to the FDA. Visit or call 1-800-FDA-1088. About Bausch + Lomb Bausch + Lomb is dedicated to protecting and enhancing the gift of sight for millions of people around the world – from birth through every phase of life. Its comprehensive portfolio of approximately 400 products includes contact lenses, lens care products, eye care products, ophthalmic pharmaceuticals, over-the-counter products and ophthalmic surgical devices and instruments. Founded in 1853, Bausch + Lomb has a significant global research and development, manufacturing and commercial footprint with approximately 13,000 employees and a presence in nearly 100 countries. Bausch + Lomb is headquartered in Vaughan, Ontario with corporate offices in Bridgewater, New Jersey. For more information, visit and connect with us on X, LinkedIn, Facebook and Instagram. Forward-looking Statements This news release may contain forward-looking statements, which may generally be identified by the use of the words “anticipates,” “hopes,” “expects,” “intends,” “plans,” “should,” “could,” “would,” “will,” “may,” “believes,” “estimates,” “potential,” “target,” or “continue” and variations or similar expressions. These statements are based upon the current expectations and beliefs of management and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These risks and uncertainties include, but are not limited to, the risks and uncertainties discussed in Bausch + Lomb’s filings with the U.S. Securities and Exchange Commission and the Canadian Securities Administrators, which factors are incorporated herein by reference. Readers are cautioned not to place undue reliance on any of these forward-looking statements. These forward-looking statements speak only as of the date hereof. Bausch + Lomb undertakes no obligation to update any of these forward-looking statements to reflect events or circumstances after the date of this news release or to reflect actual outcomes, unless required by law. *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References XIIDRA significantly reduced symptoms of eye dryness at 2 weeks in two out of four clinical studies. XIIDRA. Prescribing information. Bausch & Lomb Inc; 2023. © 2024 Bausch + Lomb. BLS.0079.USA.24 View source version on businesswire.com: Contacts Investor Contact: George Gadkowski george.gadkowski@bausch.com (877) 354-3705 (toll free) (908) 927-0735 Source: Bausch + Lomb Corporation View this news release online at: