硫酸亚铁/维生素C(Ferrous Sulfate/Ascorbic Acid) - 在研适应症：缺铁性贫血_专利_临床

概要

基本信息

药物类型

小分子化药

别名

iron sulfate (1:1)、iron(2+) sulfate (anhydrous)、iron(II) sulfate

靶点-

作用机制

维生素C补充剂

治疗领域

内分泌与代谢疾病血液及淋巴系统疾病

在研适应症

缺铁性贫血

非在研适应症-

原研机构-

在研机构-

非在研机构-

最高研发阶段批准上市

首次获批日期-

最高研发阶段(中国)批准上市

特殊审评-

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结构/序列

分子式C6H8O6

InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N

CAS号50-81-7

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关联

14

项与硫酸亚铁/维生素C 相关的临床试验

CTRI/2024/05/066760

/ Not yet recruitingN/AIIT

Ferrous Ascorbate Vs Ferrous Sulphate for the Treatment of Iron Deficiency Anemia in Children. - NIL

开始日期2025-05-12

申办/合作机构-

CTRI/2024/12/077663

/ Not yet recruitingN/AIIT

A Randomized controlled trial of Nishalauh vati in comparison withIron tablets in Panduroga w.r.t. Iron Deficiency Anemia in females. - Nil

开始日期2024-12-20

申办/合作机构-

CTRI/2024/09/073361

/ Not yet recruitingN/AIIT

Effectiveness of ferrous ascorbate as asupplementation therapy in regularvoluntaryblood donors. - Nil

开始日期2024-09-15

申办/合作机构-

100 项与硫酸亚铁/维生素C 相关的临床结果

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100 项与硫酸亚铁/维生素C 相关的转化医学

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100 项与硫酸亚铁/维生素C 相关的专利（医药）

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12,127

项与硫酸亚铁/维生素C 相关的文献（医药）

2025-03-01·Metabolism Open

Strict vegetarian diet and pregnancy outcomes: A systematic review and meta-analysis

Review

作者: Metallinou, Dimitra ; Nanou, Christina ; Sarantaki, Antigoni ; Palaska, Ermioni ; Diamanti, Athina ; Papadopoulou, Theopisti

IntroductionThe increasing adoption of strict vegetarian diets during pregnancy has raised concerns about their effects on maternal and neonatal outcomes. This systematic review and meta-analysis aimed to assess the impact of strict vegetarian diets on key pregnancy outcomes, including neonatal birth weight, small-for-gestational-age (SGA) infants, gestational diabetes mellitus (GDM), hypertensive disorders, and gestational weight gain (GWG).MethodsA comprehensive literature search across multiple databases yielded eight studies from various countries, involving a total of 72,284 participants. Primary outcomes included neonatal birth weight, SGA, preterm birth, GDM, and maternal hypertensive disorders.ResultsThe meta-analysis found that strict vegetarian diets were significantly associated with an increased risk of delivering SGA infants, with a pooled odds ratio (OR) of 2.71 (95 % confidence interval [CI]: 1.24 to 5.95; p = 0.01). Additionally, infants born to strict vegetarian mothers had lower birth weights, with some studies reporting a mean difference of 240g compared to omnivores. For GDM, no significant differences were found between strict vegetarians and omnivores, with a pooled OR of 0.64 (95 % CI: 0.37 to 1.11; p = 0.11). While vegans showed lower gestational weight gain and reduced risk of excessive weight gain, there was considerable heterogeneity in results regarding hypertensive disorders and preterm birth.ConclusionsStrict vegetarian diets during pregnancy are associated with an increased risk of SGA infants and lower birth weights. To mitigate these risks, specific dietary guidelines emphasizing adequate intake of critical nutrients such as vitamin B12, iron, omega-3 fatty acids, and iodine should be developed. Supplementation and tailored dietary counseling, incorporating fortified foods and plant-based sources like legumes, nuts, seeds, and algae-derived omega-3, are essential to ensure maternal and neonatal health. Further research is necessary to refine these guidelines and explore their impact on diverse populations.

2025-03-01·Physiology & Behavior

Investigating how eating behavior shapes mental health: A cross-sectional study

Article

作者: Türk, Öykü Peren ; Dağdelen, Selçuk ; Buyuktuncer, Zehra ; Tosun, Özgür

This study aimed to examine the relationship between eating behavior, nutritional status and mental health. It is a cross-sectional study conducted on a sample of 360 healthy individuals aged 19-64 years. The General Health Questionnaire (GHQ-12) was used to evaluate mental health and the Three-Factor Eating Scale (TFEQ-R21) was used to assess eating behavior. The Healthy Eating Index-2015 (HEI-2015) score was calculated from participants' 24 h food recalls as an indicator of diet quality. The mean age of the participants was 26.0 ± 8.40 years, and 50.6 % were female. Multivariate logistic regression model was performed. A statistically significant relationship was found between the participants' GHQ-12 score and both their emotional eating and uncontrolled eating scores (p < 0.001 for each). It was determined that individuals who had high levels of emotional eating and uncontrolled eating behaviors, along with higher dietary protein and lipid intake, and lower intake of long-chain fatty acids, were at a higher risk of mental health deterioration, according to the established model (R2 = 0.214). Dietary energy and nutrient intakes such as niacin, vitamin B12, folic acid, phosphorus, iron, sodium and carotene, as well as diet quality and BMI were not associated with mental health according to the model in this study. Eating behavior is associated with mental well-being, and nutritional status may be one of the underlying factors contributing to this association.

2025-02-01·European Journal of Nutrition

Is underweight associated with poorer diet, nutrient status, bone and cardiometabolic health, and school performance in Danish 8-11-year-olds?

Article

作者: Strandberg-Larsen, Katrine ; Damsgaard, Camilla T ; Aurup, Anne V. ; Andersen, Rikke ; Aurup, Anne V ; Damsgaard, Camilla T. ; Lauritzen, Lotte ; Biltoft-Jensen, Anja

AbstractPurposeUnderweight, i.e. low body mass index for age and sex, may indicate undernutrition, but despite high prevalence, this aspect is largely overlooked in children in high-income countries. We explored if dietary intake, nutrient status, body composition, bone mineralization, cardiometabolic markers and school performance differed in schoolchildren with underweight compared to normal- and overweight.MethodsWe used cross-sectional data from 815 Danish 8-11-year-old children collected in 2011. Intake of foods, macronutrients and key micronutrients (vitamin D, vitamin B12, calcium, iron, zinc and selenium) was assessed by 7-day dietary records. Measurements included anthropometry, dual-energy X-ray absorptiometry and tests of attention and reading skills. Fasting blood samples were analyzed for biomarkers of iron, long-chain n-3 fatty acids and vitamin D status as well as blood lipids, insulin and growth markers.ResultsEighty-three (10.2%) children had underweight and were shown to have a lower intake of energy, red meat, protein and zinc and higher intake of added sugar than children with normal- and overweight. They also had higher fish intake relative to overweight, but blood biomarkers did not differ between groups. Children with underweight had lower fat percent and bone mineralization compared to peers with normalweight, but apart from lower insulin, they did not differ in overall cardiometabolic health or school performance.ConclusionAlthough we found some differences in diet, there were no considerable differences in nutrient status, cardiometabolic health or school performance between children with underweight and their normalweight peers. However, the lower bone mineralization is a concern and needs further investigation.

100 项与硫酸亚铁/维生素C 相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
-	-	-	DB13257

研发状态

10 条最早获批的记录,

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适应症	国家/地区	公司	日期
缺铁性贫血	中国	-	-

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


EHA2022	N/A	新型冠状病毒感染	60	Sucrosomial® iron	艱膚鏇願製衊繭鹹顧鏇(鏇鹹製鬱廠鑰鏇製觸積) = 憲積構壓網繭廠願構觸夢鑰艱壓積餘淵鏇願遞 (衊鑰廠鑰膚遞鑰顧獵願 ) 更多	-	2022-06-10
				iron oral formulation (No iron support)	艱膚鏇願製衊繭鹹顧鏇(鏇鹹製鬱廠鑰鏇製觸積) = 壓觸遞築選醖夢顧淵艱夢鑰艱壓積餘淵鏇願遞 (衊鑰廠鑰膚遞鑰顧獵願 ) 更多
EHA2019	N/A	-	36	Iron Sulphate	廠糧鹽壓構憲衊簾簾壓(鏇憲襯齋壓鹽壓願繭顧) = 築鬱獵積餘鹽壓簾製廠築壓夢簾膚蓋餘夢觸淵 (簾窪範觸夢糧鹽遞築鹽 )	-	2019-05-16
				Sucrosomial® Iron	廠糧鹽壓構憲衊簾簾壓(鏇憲襯齋壓鹽壓願繭顧) = 糧糧膚積鹽顧獵鹹壓醖築壓夢簾膚蓋餘夢觸淵 (簾窪範觸夢糧鹽遞築鹽 )
EHA2019	N/A	骨髓增生异常综合征	45	Group A (sodium ferrigluconate)	淵鑰鏇齋鑰範構膚壓夢(繭壓遞蓋觸蓋夢膚窪簾) = 網糧廠淵築齋獵窪糧構積鹹衊簾憲餘衊鏇淵窪 (繭顧範網鑰蓋鬱襯艱蓋 ) 更多	-	2019-05-16
				Group B (sucrosomial iron)	淵鑰鏇齋鑰範構膚壓夢(繭壓遞蓋觸蓋夢膚窪簾) = 鏇艱願範憲獵鏇糧艱願積鹹衊簾憲餘衊鏇淵窪 (繭顧範網鑰蓋鬱襯艱蓋 ) 更多
ASN2018	N/A	霍奇金淋巴瘤 MDA-LDL \| NTBI \| TSAT ... 更多	-	Oral ferrous sulfate 105mg	繭壓糧淵願廠範窪繭醖(窪襯簾網衊簾齋鑰醖膚) = 襯鏇壓蓋鹹衊鏇憲糧壓衊選膚蓋壓遞膚願範壓 (鹽膚構製獵觸廠憲鬱壓, 104 ~ 320) 更多	积极	2018-10-23
				Oral Iron Administration (OIA) (Healthy volunteers)	遞憲選餘範網壓醖願夢(積簾獵願夢廠簾鑰糧鹽) = 顧鏇憲糧簾廠顧願選網簾壓繭構觸簾鏇壓簾繭 (鹽選簾觸齋淵齋獵齋選, 68 ~ 124)
EHA2015	N/A	骨髓增生异常综合征	107	ERYTHROPOIETIN (No support)	(糧築網夢構壓壓選網鏇) = 艱積糧構鏇壓窪鹹製鏇選鑰繭鏇選鏇積範膚窪 (顧顧範選壓夢範網製衊 ) 更多	-	2015-05-21
				Epo support	(糧築網夢構壓壓選網鏇) = 鑰醖醖襯襯憲觸築觸積選鑰繭鏇選鏇積範膚窪 (顧顧範選壓夢範網製衊 ) 更多
DOPPS (ASN2012)	N/A	TSAT \| ferritin \| hemoglobin	-	IV Iron Dose	(憲餘鹹願襯顧觸醖窪襯) = 觸製夢積遞構遞構顧顧顧簾壓夢醖窪衊壓淵糧 (糧簾餘鏇願獵廠選糧選 ) 更多	不佳	2012-10-30
				IV Iron (TSAT < 30%)	(憲餘鹹願襯顧觸醖窪襯) = 壓鏇鬱選齋膚餘鹹襯範顧簾壓夢醖窪衊壓淵糧 (糧簾餘鏇願獵廠選糧選 ) 更多
ASN2010	N/A	慢性肾病	112	IV Iron	膚繭廠衊範餘壓繭鑰願(艱選憲鏇繭鏇觸襯鏇鬱) = After IVfe, there were significant ↑ ’s in %fe 遞鹽遞簾壓獵構齋衊遞 (觸齋夢淵製廠憲構憲醖 ) 更多	积极	2010-11-16