Iptacopan

☝ 点击上方 一键预约 ☝   最新最热的医药健康新闻政策 11 月 28 日上午，国家医保局公布了《2024年版国家医保药品目录》。今年共计有 91 种药品新增进入国家医保药品目录，其中 65 个是国内企业，占比超过 70%。同时 ，有 43 种临床已被替代或长期未生产供应的药品被调出。本轮调整后，国家医保药品目录内药品总数达到 3159 种，其中西药 1765 种、中成药 1394 种。中药饮片部分 892 种。 在备受瞩目的谈判/竞价环节，今年共计有 117 种目录外药品参与，其中 89 种药品谈判或竞价成功，谈判成功率为 76%，平均降价 63%，成功率和价格降幅均与往年基本相当。其中，创新药的谈判成功率达到了 90% 以上。    三款双抗入选 今年，有三款双抗成功通过谈判入选医保目录。    两款 ADC 谈判成功    三代 EGFR-TKI 目前，国内已有 6 款三代 EGFR-TKI 获批上市，包括 1 款进口产品和 5 款国产。本次谈判中，今年上半年刚获批的倍而达药业的瑞齐替尼、圣和药业的瑞厄替尼也成功入围。至此， 6 款三代 EGFR-TKI 全部进入医保目录。 从纳入医保的适应症范围来看，奥希替尼、阿美替尼、贝福替尼、伏美替尼已获批的适应症已全部纳入。瑞齐替尼和瑞厄替尼后半年新获批的一线适应症尚未纳入。    抗肿瘤药物 西药中，本次有 25 个抗肿瘤药物通过谈判成功纳入，包括 15 款化药，10 款生物药。生物药中，除了前述介绍的 2 款 ADC 和 2  款双抗，还有 4 款单抗入选，分别为强生 CD38 单抗达雷妥尤单抗 (皮下注射)、迈博太科 EGFR 单抗西妥昔单抗β注射液、石药集团 PD-1 单抗恩朗苏拜单抗、誉衡生物 PD-1 单抗赛帕利单抗。    糖尿病药物 本次谈判药品中，有 6 款糖尿病药物被纳入医保。其中，诺和诺德的依柯胰岛素注射液今年 6 月刚在国内获批用于治疗成人 2 型糖尿病。它只需要一周注射一次，可有效改善胰岛素治疗依从性。    13 款罕见病药物纳入 本次调整共新增 91 种药品中，罕见病用药有 13 种，其中今年 4 月获批上市的盐酸伊普可泮胶囊被纳入，用于治疗既往未接受过补体抑制剂治疗的阵发性睡眠性血红蛋白尿症（PNH）成人患者 截图来源：Insight 数据库整理    医保调出品种 需要注意的是，对本次目录调整中续约失败被调出的协议期内谈判药品，为保障用药连续性，给予其 6 个月的过渡期，2025 年 6 月底前医保基金可按原支付标准继续支付。  截图来源：Insight 数据库整理    小结 据介绍，自国家医保局成立以来，已连续 7 年开展药品目录调整工作，累计将 835 种药品新增进入国家医保目录，其中谈判新增 530 种，竞价新增 38 种。与此同时，也有 438 种药品被调出目录，这些药品主要包括疗效不确切或易滥用、临床已被淘汰、长期未生产供应且可被其他品种替代的药品。 （来源：Insight数据库） 药闻康策 新媒体矩阵微信公众号 点击下方  一键关注 【免责声明】 1.“药闻康策”部分文章信息来源于网络转载是出于传递更多信息之目的，并不意味着赞同其观点或证实其内容的真实性。如对内容有疑议，请及时与我司联系。2.“药闻康策”致力于提供合理、准确、完整的资讯信息，但不保证信息的合理性、准确性和完整性，且不对因信息的不合理、不准确或遗漏导致的任何损失或损害承担责任。3.“药闻康策”所有信息仅供参考，不做任何商业交易或医疗服务的根据，如自行使用“药闻康策”内容发生偏差，我司不承担任何责任，包括但不限于法律责任，赔偿责任。 欢迎转发分享、点赞、点在看

Max to immediately begin process to provide humanitarian access for Fabhalta® (iptacopan) in collaboration with its network of partner hematologists across 53 countries People living with the rare blood disease in low-middle income countries require frequent blood transfusions, experience debilitating symptoms of fatigue and without treatment may progress to more serious life-threatening diseases The Max Foundation and Novartis have collaborated to improve access to medicines in low-resource countries for more than two decades SEATTLE, Dec. 6, 2024 /PRNewswire/ -- The Max Foundation (Max), a global nonprofit organization dedicated to accelerating health equity by delivering medication, technology, and supportive services to patients worldwide, today announced it will expand its collaboration with Novartis to include Fabhalta® (iptacopan), providing access to innovative treatment in low resource countries for PNH, a rare and debilitating blood disease that causes red blood cells to break apart. "We are thrilled to expand our reach to include people living with PNH in low-resource countries without access to an innovative treatment for this life-threatening condition," said Pat Garcia-Gonzalez, CEO of Max. "This collaboration reaffirms the deeply shared value of health equity for both organizations by making the latest treatment approved for the disease available at no cost, fulfilling our mission to accelerate health equity and enabling people to live with dignity and hope." PNH is caused by a genetic flaw that affects how red blood cells and platelets work. Only about 6 per 1 million people are diagnosed with it each year. People with PNH have sudden symptoms, including fatigue, weakness, increased heart rate, or shortness of breath, triggered by stressors like physical exertion or infection. During these episodes, red blood cells are broken down earlier than they should be, which causes patients to pass dark-colored urine. If PNH isn't treated, it can cause anemia, chronic kidney disease, or blood clots. "For more than 20 years, Novartis has successfully partnered with The Max Foundation to advance health equity by providing access to our innovative oncology medicines. Together, we have reached more than 100,000 patients by now, delivering sustainable and profound impact on communities around the globe. Novartis is proud to further expand our strong partnership, thereby accelerating early access for PNH patients in need," said Lutz Hegemann, President, Global Health at Novartis. The program will initially focus on identifying partner physicians ready to treat PNH and creating access pathways into 53 countries in Sub-Saharan Africa, Latin America, the Caribbean, and Southeast Asia and Asia Pacific. In addition to medication access, Max is seeking to collaborate with medical experts to strengthen health systems by providing education and training, identifying other potential collaborators in low- and middle-income countries, building capacity at medical institutions and facilitating conversations and partnership engagement to expand access to treatment. Max and Novartis have collaborated to improve access to innovative medicines since 2001. Starting with access to medicines for chronic myeloid leukemia and gastrointestinal stromal tumors, the collaboration has expanded to include advanced breast cancer and multiple rare diseases. Novartis is a member of Max's Humanitarian Partnership for Access to Critical Treatments (Humanitarian PACT), a collaboration among professional, nonprofit, and commercial organizations that share the commitment of the foundation to increase global access to treatment, care, and support for people living with cancer and other critical illnesses. Members of the Humanitarian PACT agree to invest resources and/or their unique organizational knowledge and capabilities to support the expansion of Max's proven treatment access model. About The Max Foundation The Max Foundation is a global health nonprofit organization dedicated to accelerating health equity. For 26 years, Max has pioneered practical, scalable, high-quality solutions to bring lifesaving treatments and patient-centered health care to more than 100,000 people living with cancer and critical illness in low- and middle-income countries. Max believes in a world where all people can access high-impact medicines, where geography is not destiny, and where everyone can strive for health with dignity and with hope. Learn more at . SOURCE The Max Foundation WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED