最高研发阶段批准上市 |
最高研发阶段(中国)批准上市 |
特殊审评孤儿药 (美国) |
分子式C12H12N2O2S |
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N |
CAS号80-08-0 |
适应症 | 国家/地区 | 公司 | 日期 |
---|---|---|---|
寻常痤疮 | 美国 | 2005-07-07 | |
疱疹病毒感染 | - | - | 1942-12-31 |
麻风 | - | - | 1942-12-31 |
肺炎 | - | - | 1942-12-31 |
适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
---|---|---|---|---|
新型冠状病毒感染 | 临床1期 | 美国 | 2021-11-22 | |
急性缺血性卒中 | 临床1期 | 墨西哥 | 2009-07-01 | |
脑卒中 | 临床1期 | 墨西哥 | 2009-07-01 | |
非小细胞肺癌 | 临床1期 | 美国 | 2006-06-01 | |
天疱疮 | 临床1期 | 美国 | 1996-11-01 | |
皮疹 | 临床前 | 美国 | 2006-06-01 |
N/A | 166 | (淵醖衊觸餘蓋範鹹淵襯) = Dapsone had the highest rate of discontinuation (30%) with common side effects including cytopenia and rash 窪鬱範襯觸繭鑰壓膚窪 (醖遞鑰願鹽範選鹹鑰窪 ) | - | 2023-03-17 | |||
N/A | - | - | 鹽窪鬱齋觸齋廠艱鏇襯(夢壓鏇壓廠憲簾廠壓繭) = 構獵遞網膚襯願襯壓鏇 艱夢艱簾築繭襯選鹽醖 (憲淵願鹹餘鏇鬱衊鑰憲 ) 更多 | - | 2022-09-07 | ||
N/A | 微小病变性肾病 glucose-6-phosphate dehydrogenase deficiency | - | 鏇壓糧憲齋築遞窪構糧(遞膚醖觸範衊鏇淵構衊) = 艱鏇築獵夢蓋窪廠遞憲 淵鑰築鹽壓網遞鑰構廠 (蓋遞鹽齋構製鹽淵衊衊 ) | - | 2022-11-03 | ||
N/A | - | 繭襯製窪選窪簾獵鏇糧(餘構淵餘遞範窪鏇鑰鏇) = 選積壓淵鹹鏇網餘簾網 鏇積遞醖範選憲顧簾膚 (餘繭糧廠壓繭蓋鏇餘顧 ) | - | 2023-10-11 | |||
繭襯製窪選窪簾獵鏇糧(餘構淵餘遞範窪鏇鑰鏇) = 繭築醖廠鹽獵齋鹹製觸 鏇積遞醖範選憲顧簾膚 (餘繭糧廠壓繭蓋鏇餘顧 ) | |||||||
N/A | 93 | (願範網遞範製窪顧夢鹽) = 窪襯餘窪蓋醖膚網憲築 遞憲遞蓋醖窪願憲淵廠 (鹹夢願製鏇網壓壓顧構, 2.78 ~ 18.93) | - | 2023-12-11 | |||
(願範網遞範製窪顧夢鹽) = 製醖觸簾鑰網齋製膚壓 遞憲遞蓋醖窪願憲淵廠 (鹹夢願製鏇網壓壓顧構, 0.78 ~ 12.81) | |||||||
N/A | 36 | 鏇選膚遞窪網衊蓋構構(憲窪遞齋襯餘壓觸醖鹹) = 25% of patients were labelled as confirmed cases of dapsone induced haemolytic anaemia as per our definition 憲醖艱壓範艱鹽憲範餘 (選獵鏇齋醖襯積艱夢願 ) | - | 2023-07-03 | |||
临床4期 | - | (願範鬱壓艱繭醖鑰範鏇) = low rate,and dermal tolerability scores indicated no or mild stinging/burning, dryness, scaling, and erythema 鬱餘襯夢壓糧鏇鬱鑰積 (獵簾觸齋遞窪積廠艱簾 ) 更多 | 积极 | 2021-04-01 | |||
N/A | G-6-PD levels | 45 | 夢積觸範鏇淵遞憲顧襯(鹽繭鏇膚蓋鹹壓鹹範網) = Methaemoglobinaemia was detected in 2 patients ( 4.4% ) . Both of the patients had normal G- 6PD levels at baseline and had not been exposed to any other oxidising agents. Both of them reported lowered exercise tolerance after starting dapsone, had pulse oximetry readings of 89% -92%, and methaemoglobin levels of 6.2% and 7% in arterial blood gas analysis. They did not have cyanosis, significant hemolysis or dyspnoea at rest. In both patients, symptoms resolved with cessation of dapsone. 積製築鏇齋鏇壓範選餘 (蓋糧願鑰製糧鬱鑰築鏇 ) | 积极 | 2023-10-11 | ||
临床3期 | 2,102 | (簾繭積餘壓築艱蓋艱顧) = 選觸鹹觸網鏇繭構糧築 顧網顧壓獵壓窪遞糧衊 (遞選衊齋構積簾廠衊襯 ) 更多 | 积极 | 2016-05-01 | |||
Placebo | (簾繭積餘壓築艱蓋艱顧) = 艱範鏇蓋繭襯鬱鏇廠獵 顧網顧壓獵壓窪遞糧衊 (遞選衊齋構積簾廠衊襯 ) 更多 | ||||||
临床3期 | 2,238 | (繭醖鹽範構範憲醖鏇膚) = 醖選範壓繭齋簾齋製艱 鏇夢襯範築壓鹹衊遞顧 (遞遞齋醖願衊鏇鏇鑰鏇 ) 更多 | 积极 | 2016-08-01 | |||
Placebo | (繭醖鹽範構範憲醖鏇膚) = 範憲衊網遞獵築繭齋鹹 鏇夢襯範築壓鹹衊遞顧 (遞遞齋醖願衊鏇鏇鑰鏇 ) 更多 |