Omega-3-acid ethyl esters(Trygg Pharma AS)

WASHINGTON, June 5, 2025 /PRNewswire/ -- The Lupus Foundation of America is proud to announce the seven recipients of the 2025 Gina M. Finzi Memorial Student Summer Fellowship Program (Finzi). This program supports undergraduate, graduate, and medical students conducting lupus-focused research under the guidance of experienced mentors at academic institutions in the US, Canada or Mexico. Its purpose is to inspire medical and graduate students to pursue lupus research, helping to build the future pipeline of experts across North America. This year's Finzi Fellows will spend the summer investigating unanswered questions in lupus including: How skin lesions heal – uncovering the biological steps the body takes to resolve lupus-related skin damage. The brain and nerves in lupus – exploring how lupus affects the brain, spinal cord, and nerves, including changes in brain structure and function. Mental health and self-care – studying how chronic stress from "superwoman schema" affects a patient's ability to engage in self-management. Lupus in the kidneys – identifying the biological and social factors that drive the development of lupus nephritis (lupus-related kidney disease), a serious kidney complication. The role of diet and nutrients – two studies in this area, examining how dietary compounds like omega-3 fatty acids influence immune cells and disease activity, as well as how nutrition may impact symptoms and flares. Lupus and the X chromosome – investigating how changes in genes located on the X chromosome may increase lupus risk, especially in women. "Students pursuing their graduate or medical education in biomedical fields are poised to become the next generation of scientists, and recognition of their efforts through the Gina M. Finzi Student Summer Fellowship Program, and the excitement for their research, helps inspire students to continue investigations in the field of lupus and autoimmunity in their future careers," shared Montserrat Anguera, PhD, Associate Professor, Department of Biomedical Sciences, University of Pennsylvania and 2025 Finzi grantee mentor. Throughout the fellowship, Finzi recipients work closely with seasoned clinical investigators and biomedical scientists who provide guidance and foster their development as emerging scientists. This mentorship is a vital part of the program, offering essential support as students begin to shape their careers in lupus research. Launched in 1984, the Gina M. Finzi Memorial Student Summer Fellowship Program was established in memory of Gina M. Finzi, daughter of former Lupus Foundation of America President Sergio Finzi, PhD. Many past fellows have gone on to become leaders in the field, advancing groundbreaking research in lupus. "The future of lupus research is in the hands of the students that will be ushering in the next breakthroughs in the field," shared Joy Buie, Ph.D, MSCR, RN, Vice President of Research at Lupus Foundation of America. "The Gina M. Finzi Memorial Student Summer Fellowship Program is uniquely positioned to ensure investments are made in the brightest, most innovative young minds. With guidance from mentors, these Finzi Fellows will gain the experiences needed to support a research career focused on closing gaps in lupus diagnosis, treatment and care." The research conducted by Finzi Fellows will contribute to a variety of crucial areas within the lupus field: Grace Crossland Dartmouth College, Geisel School of Medicine Project Title: Defining the role of mucosal-associated invariant T (MAIT) cells in cutaneous lupus erythematosus Mentor: Sladjana Skopelja-Gardner, PhD Vanessa Estrada Department of Microbiology, Genetics, & Immunology, Michigan State University Project Title: Omega-3 Fatty Acids: Omega-3 Effects on Interferon Gene Methylation in Lupus Macrophages Mentor: James J. Pestka, PhD Rohan Gupta The Feinstein Institutes for Medical Research Project Title: Determining the Role of the Aryl Hydrocarbon Receptor (AHR) in NPSLE Mentor: Betty Diamond, MD Jerik Leung Emory University Project Title: Using Photovoice to Understand Self-Management Behaviors in Lupus Mentors: S. Sam Lim, MD, MPH; Cam Escoffery, PhD, MPH, CHES Sara Smith The Regents of University of California, San Francisco Project Title: Uncovering the Molecular Underpinnings of Lupus Nephritis with Multi-Omic Analysis Mentor: Gabriela K. Fragiadakis, PhD Emma Welter The Trustees of the University of Pennsylvania Project Title: Investigating the Impact of Lupus-Like Disease on the Inactive X Chromosome in Age-Associated B Cells Mentor: Montserrat Anguera, PhD Jin Xuan Zhou Hospital for Sick Children, Toronto Project Title: Diffusion Tensor Imaging Metrics and Neurocognitive Function in cSLE Mentor: Andrea Knight, MD, MSCE Learn more about the 2025 Gina M. Finzi Memorial Student Summer Fellowship recipients, here. About the Lupus Foundation of America: The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world's cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus. About Lupus: Lupus is an unpredictable and misunderstood autoimmune disease that ravages different parts of the body. It is difficult to diagnose, hard to live with, and a challenge to treat. Lupus is a cruel mystery because it is hidden from view and undefined, has a range of symptoms, hits out of nowhere, and has no known cause and no known cure. Its health effects can range from a skin rash to a heart attack. Lupus is debilitating and destructive, and can be fatal, yet research on lupus remains underfunded relative to its scope and devastation. MEDIA CONTACT Shannon Brown [email protected] 202-763-5485 SOURCE Lupus Foundation of America, Inc. WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED

点击“蓝字”关注我们 心脏病的“隐形推手”：Omega-3缺乏 缺血性心脏病是全球主要死亡原因之一，目前约有2亿人被诊断患有此病。虽然现有的治疗方法包括药物、冠状动脉搭桥手术和经皮冠状动脉介入治疗（PCI），但这些方法的疗效有限。Omega-3脂肪酸具有抗炎、抗血栓和改善血脂的作用，能够降低缺血性心脏病的风险。然而，关于不同地区Omega-3摄入水平对IHD风险的影响，尤其是结合社会经济因素的研究仍较为匮乏。 最近发表在BMC Cardiovascular Disorders上的一项研究确定了膳食omega-3（ω-3）脂肪酸（FA）在全球缺血性心脏病（IHD）发展中的作用。 本研究利用《全球疾病负担（GBD）2021》数据集，分析了全球范围内Omega-3摄入不足与缺血性心脏病之间的关系。 2021年，全球因Omega-3摄入不足导致的缺血性心脏病共造成约1550万伤残调整生命年（DALYs）和超过63.7万例死亡，分别占所有IHD相关DALYs和死亡的8.2%和7%。从1990年到2021年，与Omega-3摄入不足相关的IHD致残率和死亡率分别增加了0.6%和0.74%。然而，在调整人口老龄化因素后，年龄标准化的DALYs和死亡率每年下降了近2%。 性别差异：男性更“受伤”? 男性因Omega-3摄入不足导致的IHD致残率和死亡率高于女性。每10万男性中，DALYs为216，死亡率为8.5；而每10万女性中，DALYs为147，死亡率为6.5。然而，在75至79岁的男性中，这一趋势有所逆转。 地区差异：南亚成“重灾区”? 南亚地区的IHD致残率和死亡率最高。在亚太地区的高收入国家，因Omega-3摄入不足导致的IHD死亡率则低得多。中亚的年龄标准化IHD率最高，每10万人中有678例DALYs和33例死亡，其次是北非、南亚和撒哈拉以南非洲。印度因Omega-3摄入不足导致的IHD负担最重，每10万人中有5066例DALYs和176例死亡。中国、美国和巴基斯坦紧随其后。 阿富汗的年龄标准化DALYs最高，每10万人中有1179例。叙利亚、乌兹别克斯坦、也门和苏丹的年龄标准化DALYs也较高，其中叙利亚的年龄标准化死亡率最高，每10万人中有49例。马尔代夫、日本和新加坡的IHD发病率最低，与Omega-3摄入不足的关系最小。 时间趋势 随着时间的推移，26个国家的IHD致残率和31个国家的IHD死亡率因Omega-3摄入不足而增加。纳米比亚的DALYs和死亡率增幅最大，而马来西亚的降幅最为显著。几乎所有地区的年龄标准化IHD率均呈下降趋势，但撒哈拉以南非洲除外。 经济越好，心脏越“轻松”？ 研究发现，随着社会经济指数（SDI）的提高，与Omega-3摄入不足相关的年龄标准化IHD率有所下降，但这种相关性在较低社会经济群体中较弱。 饮食建议小贴士 01 多吃鱼，心脏更健康 每周至少吃两次富含Omega-3的鱼类，如三文鱼、沙丁鱼或鲭鱼。如果不喜欢吃鱼，可以考虑鱼油补充剂。 02 坚果：小小一颗，大大益处 每天吃一小把坚果，如核桃、杏仁或亚麻籽，它们都是Omega-3的良好来源。 03 烹饪用油换一换 将日常烹饪油换成富含Omega-3的油，如亚麻籽油或菜籽油，既健康又美味。 04 早餐加点“健康料”? 在早餐的燕麦粥或酸奶中加入一勺奇亚籽或亚麻籽粉，轻松补充Omega-3。 05 减少加工食品摄入 加工食品通常含有大量不健康的脂肪，会抵消Omega-3的益处。尽量选择天然、未加工的食物。 06 与家人一起健康饮食 鼓励家人一起多吃富含Omega-3的食物，全家人的心脏健康都能得到改善。 拯救心脏，从餐桌开始 这项研究揭示了Omega-3摄入不足与缺血性心脏病负担之间的显著关联。尽管在研究期间，年龄标准化的IHD致残率和死亡率有所下降，但全球范围内的相关事件数量仍在增加，这凸显了制定针对性政策以降低风险的迫切性。例如，在南亚等高危地区推广富含Omega-3的食物（如鱼类和坚果）可能有助于减少IHD的致残率和死亡率。 未来需要更多研究来验证这些结果，并探索其他可能导致IHD发病和死亡的风险因素，同时监测饮食习惯的改善如何在全球范围内改善患者预后。 参考文献：Xu, J., Peng, T., Kong, L. et al. A global analysis of the burden of ischemic heart disease attributable to diet low in ω-3 fatty acids between 1990 and 2021. BMC Cardiovasc Disord 25, 188 (2025). https://doi-org.libproxy1.nus.edu.sg/10.1186/s12872-025-04620-z 声明：本文仅供医疗卫生专业人士了解最新医药资讯参考使用，不代表本平台观点。该等信息不能以任何方式取代专业的医疗指导，也不应被视为诊疗建议，如果该信息被用于资讯以外的目的，本站及作者不承担相关责任。 最新《心肾代谢时讯》读者专属微信交流群建好了，快快加入吧！扫描左边《心肾代谢时讯》小助手二维码（微信号：CKM-Times），回复“心肾代谢读者”，ta会尽快拉您入群滴！ （来源：《心肾代谢时讯》编辑部） 版权声明 版权属《心肾代谢时讯》所有。欢迎个人转发分享。其他任何媒体、网站未经授权，禁止转载。