别名 Diffuse Scleroderma、Diffuse Sclerosis、PROGRESSIVE SYSTEMIC SCLEROSIS + [48] |
简介 A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. |
靶点 |
作用机制 IL-31RA抑制剂 |
在研机构 |
非在研适应症- |
最高研发阶段批准上市 |
首次获批国家/地区 日本 |
首次获批日期2022-03-28 |
靶点 |
作用机制 CD19调节剂 |
在研机构 |
原研机构 |
最高研发阶段批准上市 |
首次获批国家/地区 中国 |
首次获批日期2021-09-01 |
开始日期2025-09-01 |
开始日期2025-07-01 |
申办/合作机构 |
开始日期2025-06-13 |