Ajax Therapeutics Appoints Alan Collis, PhD, as Senior Vice President and Head of Preclinical Development
2023-03-09
高管变更
NEW YORK--(BUSINESS WIRE)-- Ajax Therapeutics, Inc., a biopharmaceutical company applying computational chemistry and structure-based technologies to develop next generation JAK inhibitorsJAK inhibitors for myeloproliferative neoplasms (MPNs), today announced the appointment of Alan Collis, PhD, as Senior Vice President and Head of Preclinical Development. Dr. Collis brings over 25 years of drug development experience to Ajax with previous preclinical development roles at Novartis, Forma Therapeutics and Nimbus Therapeutics. At Nimbus, he managed the preclinical development of the company’s drug discovery program targeting tyrosine kinase 2 (TYK2), a member of the JAK kinase family.
“We are excited to have Alan join Ajax as we transition our lead Type II JAK2 inhibitorJAK2 inhibitor program into IND enabling studies,” said Martin Vogelbaum, CEO of Ajax Therapeutics. “His depth of experience in both oncology and immunology drug development will be invaluable as we move our lead program toward the clinic as a much-needed new targeted therapy for the majority of MPN patients who are resistant or refractory to currently available JAK2 therapies.”
“I am very pleased to be joining Ajax at this pivotal stage of drug development,” said Dr. Collis. “I look forward to working with the Ajax team in advancing the company’s next generation JAK inhibitorsJAK inhibitors that have not only demonstrated greater efficacy and JAK family selectivity than current JAK2 therapies, but also the potential to be disease modifying therapies.”
Dr. Collis joins Ajax from Syngene International where he served as Vice President of Integrated Drug Discovery and led a portfolio of 20 drug discovery programs. Prior to Syngene, he served as Senior Vice President of Preclinical Development at Nimbus Therapeutics where led the preclinical and IND activities for the company’s TYK2 and HPK-1 inhibitor programs. Previously, Dr. Collis was Executive Director, DMPK and Safety for Forma Therapeutics where he supported the company’s IDH1 and BET inhibitorIDH1 and BET inhibitor programs. He has also worked in various director level positions at Novartis Institute for Biomedical Research, Sanofi-Aventis and Rhone Poulenc Rorer. Dr. Collis received a PhD in chemistry from the University of Manchester, UK.
About Ajax Therapeutics
Ajax Therapeutics, Inc. is pursuing uniquely selective approaches to develop novel next generation JAK2 therapies for myeloproliferative neoplasms (MPNs), including Myelofibrosis. By combining the deep cancer and structural biology insights of our founding scientists with the industry’s most advanced computational drug discovery and protein structure platforms from our founding partner, Schrödinger, Inc., we aim to discover and develop more precisely designed therapies to address the significant unmet needs for patients with MPNs.
Please find more information at .
更多内容，请访问原始网站
文中所述内容并不反映新药情报库及其所属公司任何意见及观点，如有版权侵扰或错误之处，请及时联系我们，我们会在24小时内配合处理。
热门报告
立即开始免费试用!
智慧芽新药情报库是智慧芽专为生命科学人士构建的基于AI的创新药情报平台，助您全方位提升您的研发与决策效率。
立即开始数据试用!
智慧芽新药库数据也通过智慧芽数据服务平台，以API或者数据包形式对外开放，助您更加充分利用智慧芽新药情报信息。