主要目的：本研究以四川新斯顿制药股份有限公司持证的精氨酸布洛芬颗粒（规格：0.4g（以布洛芬计））为受试制剂，海南赞邦制药有限公司持证的精氨酸布洛芬颗粒（商品名：司百得，规格：0.4g（以布洛芬计））为参比制剂，进行空腹/餐后状态下人体生物等效性试验，评价受试制剂和参比制剂在健康受试者体内的生物等效性。次要目的：观察受试制剂和参比制剂在健康受试者中的安全性。

开始日期2024-07-29

申办/合作机构

四川新斯顿制药股份有限公司

CTR20241331 / CompletedN/A

精氨酸布洛芬颗粒的人体生物等效性试验

主要目的：在健康受试者体内，分别在空腹和餐后条件下，以海南赞邦制药有限公司持有的精氨酸布洛芬颗粒（商品名：司百得®；规格：0.4g（以布洛芬计））为参比制剂，研究仁合益康汇泽药业河北有限公司持有的精氨酸布洛芬颗粒（规格：0.4g（以布洛芬计），受试制剂）的人体药代动力学，评价受试制剂与参比制剂是否具有生物等效性。次要目的：观察受试制剂和参比制剂在健康受试者中的安全性。

开始日期2024-05-21

申办/合作机构

仁合益康汇泽药业河北有限公司

CTR20240906 / CompletedN/A

精氨酸布洛芬片在中国健康受试者空腹/餐后状态下单中心、随机、开放、单剂量、两制剂、两周期、双交叉生物等效性临床试验

以海南赞邦制药有限公司的精氨酸布洛芬片(规格：0.4g)作为参比制剂，评价海南赛立克药业有限公司研制的精氨酸布洛芬片(规格：0.4g)与参比制剂的生物等效性。

开始日期2024-04-23

申办/合作机构

海南赛立克药业有限公司

100 项与韧带疼痛相关的临床结果

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100 项与韧带疼痛相关的转化医学

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0 项与韧带疼痛相关的专利（医药）

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项与韧带疼痛相关的文献（医药）

2024-10-01·The Korean Journal of Pain

A critical factor in resistant piriformis syndrome cases: awareness of sacrotuberous ligament pain

Letter

作者: Ada, Ayşenur ; Alyanak, Bülent ; Dede, Burak Tayyip ; Oğuz, Muhammed ; Bağcıer, Fatih

2024-05-01·Rheumatic Disease Clinics of North America

Patient Voices in Rheumatic Immune-related Adverse Events

Review

作者: Lopez-Olivo, Maria A ; Corps, Kara N ; Terry, Oliver

Patients with cancer considering immune checkpoint inhibitor (ICI) therapy often look for health information and peer support through online communities. The authors used social media content analysis to obtain the perspectives of patients receiving ICI treatment about immune-related adverse events (irAEs), with particular focus on rheumatological symptoms. The most reported rheumatic symptom was joint pain. Other commonly reported symptoms included muscle pain, joint stiffness, arthritis, myositis, bone pain, back pain, and tendon/ligament pain. A few users reported development of rheumatic diseases. The authors' analyses allowed for cataloging and assessment of patient and caregiver experiences with ICI therapy and rheumatic irAEs.

2024-01-03·Journal of Surgical Case Reports

Body-piercing associated appendicitis in the pregnant patient incidentally discovered during Caesarian section

作者: Schadt, Jennifer ; Zalamea, Nia ; Houser, Molly ; Hungerford, Andrew

AbstractAppendicitis is the most common general surgery condition encountered in pregnant patients. Its presentation and diagnosis can be confounded by physiological changes of pregnancy causing atypical symptoms and overlap between pregnancy symptoms and appendicitis. Diagnosis of appendicitis in pregnancy is important, as pregnant persons have a much higher rate of complication from appendicitis. In this case report, we describe a patient with a history of right lower quadrant pain thought to be related to round ligament pain. Her previously undiagnosed appendicitis was discovered during routine inspection during caesarian section. The patient’s final pathology revealed a metallic foreign body, one of the rarest causes of appendicitis.