Beijing Zhenzhi Medical Technology Co., Ltd.

In this study, safety and effects of IPM001 injection on human hepatocellular carcinoma are going to be investigated, IPM001 is a multiple tumor-associated antigen (TAA) and neoantigen/tumor-specific antigen (TSA) sensitized autoimmune cell injection

In this study, safety and effects of IPM001 vaccine on human hepatocellular carcinoma are going to be investigated, IPM001 is a neoantigen/tumor-specific antigen sensitized autoimmune cell injection

主要目的 1）评价IPM001注射液治疗进展期原发性肝细胞癌患者的安全性和耐受性； 2）评估IPM001注射液的药代动力学（免疫动力学）特征； 3）确定IPM001注射液II期临床试验推荐剂量（RP2D）； 次要目的 1）评估IPM001注射液治疗进展期原发性肝细胞癌的初步临床有效性。 探索性目的 2）探索IPM001注射液诱导的免疫应答与临床疗效的相关性。