Delving into the Latest Updates on VUmc with Synapse

The goal of this clinical trial is to compare brief-intensive cognitive-behaviour therapy (CBT) with regular weekly CBT in people with anxiety-related disorders.
The main question to answer is: will brief-intensive CBT improve functioning (work, family, social) more and faster than does regular weekly CBT?
Participants will be asked to follow CBT treatment (20 sessions of 45 minutes in both conditions), and participate in 7 measurements with a total duration of 5 hours over 1 year.
Researchers will compare:
Brief-intensive CBT: 16 sessions in 2 weeks + 4 follow-up sessions within 3 months
Regular CBT with 20 weekly sessions in 6 months

开始日期2023-12-01

申办/合作机构

VUmc

NL-OMON25971

/ SuspendedN/AIIT

Exploring the effects of Street Temptations on cognitive distortions and treatment motivation within behaviorally at-risk adolescents

开始日期2021-09-01

申办/合作机构

VUmc

NL-OMON21916

/ RecruitingN/AIIT

Longitudinal prediction of progression in MS: 'The Amsterdam MS Cohort'

开始日期2021-05-25

申办/合作机构

VUmc

100 项与 VUmc 相关的临床结果

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0 项与 VUmc 相关的专利（医药）

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19,747

项与 VUmc 相关的文献（医药）

2025-02-01·Life Sciences

Retraction notice to “Rigosertib potently protects against colitis-associated intestinal fibrosis and inflammation by regulating PI3K/AKT and NF-κB signaling pathways” [Life Sci. 249 (2020) 117470]

作者: Rahmani, Farzad ; Khazaei, Majid ; Ryzhikov, Mikhail ; Hassanian, Seyed Mahdi ; Asgharzadeh, Fereshteh ; Ferns, Gordon A ; Giovannetti, Elisa ; Barneh, Farnaz ; Avan, Amir ; Parizadeha, Mohammad Reza ; Jafari, Mohieddin ; Ahmadian, Mohammad Reza

2025-02-01·European Journal of Cancer

Corrigendum to “Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry” [Eur. J. Cancer 212, 2024, 115056]

作者: Aarts, M J B ; van den Berkmortel, F W P J ; de Groot, J W B ; Bonenkamp, J J ; Bloem, M ; Vreugdenhil, G ; van den Eertwegh, A J M ; Blank, C U ; Stevense-den Boer, A M ; Holtslag, C E ; Portielje, J E A ; Boers-Sonderen, M J ; van den Bos, F ; de Glas, N A ; Özkan, A ; van der Veldt, A A M ; Wouters, M W J M ; Kapiteijn, E ; Haanen, J B ; Suijkerbuijk, K P M ; van Rijn, R S ; Piersma, D ; Blokx, W A M ; Hospers, G A P

2025-01-15·The Journal of Maternal-Fetal & Neonatal Medicine4区 · 医学

Reproductive outcomes in women with mild intrauterine adhesions; a systematic review and meta-analysis

4区 · 医学

Review

作者: Hooker, Angelo B. ; Mansvelder, Floor J. ; Elbers, Roy G. ; Frijmersum, Zayel

BACKGROUNDModerate to severe intrauterine adhesions (IUAs) may greatly impact fertility, predisposing to pregnancy and obstetric complications. The impact of mild IUAs on reproductive performance remains unclear. A systematic review and meta-analysis was performed to examine the long-term reproductive outcomes in women with hysteroscopic identified and treated mild IUAs mild intrauterine adhesions (IUAs).METHODSAn electronic literature search was conducted using MEDLINE and EMBASE from inception to June 2019. All prospective cohort, cross-sectional studies or randomized controlled trials Clinical trials in which reproductive outcomes of women with mild IUAs, were reported were included.RESULTSFive studies, reporting on reproductive outcomes of 229 women with hysteroscopic identified and treated mild IUAs, were included. The pregnancy rate was 62.3% (142 of 228; 95% CI: 0.55-0.72, I² 25%, p = .21) and in 86.6% (123 of 142) a live birth was encountered (95% CI: 0.71-0.97) with 83.1% (108 out of 130) term deliveries (95% CI: 0.53-0.95). A miscarriage was reported in 10% (13 of 130; 95% CI: 0.02-0.26). Due to the lack of a control group, reproductive outcomes were compared to a general population. Pregnancy and live birth rates were significantly lower in women with identified and treated mild IUAs, 90% versus 62.3% and respectively 99.5% versus 86.6%. The miscarriage rate was similar. Data on obstetric and neonatal outcomes are lacking.CONCLUSIONSWomen with hysteroscopic identified and treated mild IUAs seem to have lower pregnancy and live birth rate compared to the general population. Future studies consisting of a large cohort of women with hysteroscopic identified and treated IUAs with structural follow-up and a control group are needed to confirm our findings.

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