来源: Pharmaceutical Technology
The vaccine demonstrated an excellent safety profile and 93.28% protective efficacy 14 days after injection. Credit: WestVac BioPharma Co., Ltd./ CNW.
WestVac Biopharma has announced that the Chinese authorities have granted emergency use authorisation (EUA) for coviccine trivalent XBB.1.5-recombinant Covid-19 trivalent (XBB.1.5+BA.5+delta) protein vaccine (Sf9 cell). This marks the world’s first Covid-19 vaccineCovid-19 vaccine approved for emergency use against XBB descendent lineages of SARS-CoV-2. 来源: Pharmaceutical Technology
ReportsLOA and PTSR Model - influenza [strains A/H1N1 + A/H3N2 + B/Hong Kong] vaccine GlobalData 来源: Pharmaceutical Technology
ReportsLOA and PTSR Model - influenza [strain A/Singapore/INFIMH-16-0019/2016 (H3N2)] (monovalent) vacci... GlobalData The subunit antigen in the vaccine has been based on the structure of the targeting S-RBD and HR proteins of the XBB and BA.5 subvariants.
It is self-assembled into stable trimeric protein particles with the addition of squalene-based oil-in-water emulsion adjuvant following purification and mixing.
Trials demonstrated that the vaccine induced a high titer of neutralising antibodies against several subvariants, including Omicron subvariants XBB.1.5, XBB1.16, XBB1.9.1, XBB.2.3, BA.2.75, BQ.1, BA.5 and BF.7.
The vaccine demonstrated an excellent safety profile and 93.28% protective efficacy against XBB.1, XBB.1.5, and XBB1.9, 14 days after injection.
The results indicated that coviccine trivalent XBB.1.5 is a Covid-19 vaccineCovid-19 vaccine with a broad spectrum to tackle several prevalent subvariants in China and globally.