ω-3鱼油脂肪乳(Fish Oil Triglycerides) - 在研适应症：胆汁淤积_专利_临床

概要

基本信息

药物类型

小分子化药

别名

ω-3 Fish Oil Fat Emulsion、精制鱼油/卵磷脂、Omegaven

+ [1]

靶点-

作用机制-

治疗领域

消化系统疾病

在研适应症

胆汁淤积

非在研适应症-

原研机构

Fresenius Kabi AG

在研机构

Fresenius Kabi USA LLC

非在研机构-

最高研发阶段批准上市

首次获批日期

美国 (2018-07-27),

胆汁淤积

最高研发阶段(中国)-

特殊审评快速通道 (美国)、孤儿药 (美国)

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关联

192

项与 ω-3鱼油脂肪乳相关的临床试验

NCT06274788 / Not yet recruiting临床4期

Title: A Single-arm, Open-label, Prospective, Multicenter Safety Study to Evaluate the Occurrence of Essential Fatty Acid Deficiency (EFAD) in Pediatric Patients With Parenteral Nutrition-associated Cholestasis (PNAC) Who Require More Than Eight Weeks of Omegaven Treatment

This study will demonstrate safety in pediatric patients with Parenteral Nutrition-Associated Cholestasis treated with Omegaven®, which is indicated as a source of calories and fatty acids in this patient population

开始日期2024-05-01

申办/合作机构

Fresenius Kabi USA LLC

NCT06279793 / Recruiting临床2期

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients: a Phase II Multicenter Trial: A Double-blind, Randomized, Placebo-controlled Trial.

The proposing study is a randomized, double-blind, controlled trial of about 120 patients in 10 centers in Germany. This trial will be started in Germany and recruited mainly at powerful German heart centers only.
In this prospective randomized controlled blinded multicenter trial, a total of 120 high-risk cardiac surgery patients will receive either standard of care + OMEGAVEN at 0.20 g/kg ideal body weight (IBW) versus placebo + standard of care.

开始日期2024-02-15

申办/合作机构

GCP Service International Ltd & Co KG

[+2]

IRCT20231031059911N1 / RecruitingN/AIIT

Evaluation the effect of fish oil supplementation on glucose homeostasis and inflammatory markers in patients with mild burn

开始日期2024-01-21

申办/合作机构

Zanjan University of Medical Sciences

100 项与 ω-3鱼油脂肪乳相关的临床结果

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100 项与 ω-3鱼油脂肪乳相关的转化医学

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100 项与 ω-3鱼油脂肪乳相关的专利（医药）

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8,109

项与 ω-3鱼油脂肪乳相关的文献（医药）

2024-05-01·Food chemistry

The same species, different nutrients: Lipidomics analysis of muscle in mud crabs (Scylla paramamosain) fed with lard oil and fish oil

Article

作者: Wang, Ziyi ; Tang, Mengyao ; Zhang, Ziping ; Ye, Zihao ; Zhang, Yi ; Xu, Yifang ; Huang, Weiqing ; Liu, Jinjin ; Wang, Xuexi ; Cui, Shihui

Aiming to assess the effects of lard oil (LO) and fish oil (FO) on the nutritional value of mud crabs (Scylla paramamosain), non-targeted lipidomics analysis was performed on the muscle of crabs after eight weeks of feeding trail. Compared to FO, dietary LO reduced the content of phosphatidylethanolamine (PE) and phosphatidylserine (PS) with 18:0 bound at sn-1/3 site, the content of ether phospholipids containing 20:5n-3 (EPA) and 22:6n-3 (DHA) combined at sn-2 site, and increased the content of ether PE containing 18:0 and 18:1n-9. Furthermore, the deposition of 16:0, 16:1n-7, 18:2n-6, 18:3n-3, 20:4n-6, EPA and DHA at each site of PE, PS, phosphatidylcholine and/or triacylglycerols were reduced by dietary LO, while the DHA content at the sn-2 position of PE was increased. In conclusion, the nutritional value of mud crabs was reduced by dietary LO with the manifestation of variation in FA composition and positional distribution on phospholipids.

2024-04-01·Journal of affective disorders

Omega-3 polyunsaturated fatty acids supplementation improves memory in first-diagnosed, drug-naïve patients with depression: Secondary analysis of data from a randomized controlled trial

Article

作者: Zhao, Tingyu ; Wang, Lu ; Tang, Hui ; Chen, Jindong ; Xue, Ying ; Xie, Kaiqiang ; Tang, Mimi ; Guo, Jimin ; Liu, Ting

INTRODUCTION:

Cognitive impairments are found in most patients with major depressive disorder (MDD). It is believed that low Omega-3 polyunsaturated fatty acids (n-3 PUFAs) level raise the risk of anxiety, depressive symptoms and cognition dysfunction. Since our previous research has found n-3 PUFAs supplementation improves anxiety in MDD, this study was to further explore the effectiveness on cognitive impairment among depressed patients.

METHODS:

A total of 72 venlafaxine treated outpatients with first-diagnosed, drug-naïve depression were enrolled. Daily n-3 PUFAs supplementation (2.4 g/d of fish oil, including 1440 mg eicosapentaenoic acid and 960 mg of docosahexaenoic acid) or placebo was used for 12 weeks. Cognitive function, measure by repeatable battery for the assessment of neuropsychological status ([RBANS]) scores, was compared over time.

RESULTS:

Immediate memory, delayed memory and RBANS total scores were significant higher in both groups at week 4 and week 12 compared with baseline. Both groups exhibited improvement on attention scores at week 12. No significant differences were observed comparing n-3 PUFAs with placebo groups in the improvement of total RBANS scores and other subscales except in the change of immediate memory at both week 4 and week 12 (p < 0.05).

LIMITATIONS:

Sample size was relatively low. Moreover, multiple ethnic populations and the income of patients should be considered. Lastly, we used raw scores instead of the standardized scores of RBANS.

CONCLUSION:

N-3 PUFAs supplementation yielded a small but statistically significant improvement on immediate memory in first-diagnosed, drug-naïve depressed patients. While, antidepressant treatment resulted in significant improvement of cognitive function.

2024-04-01·The Journal of nutritional biochemistry

Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain

Article

作者: Luo, Zhi ; Song, Yu-Feng ; Zheng, Fei-Fei ; Lai, Xiao-Hong ; Hogstrand, Christer ; Wang, Ling-Jiao

The mitochondrial matrix serves as the principal locale for the process of fatty acids (FAs) β-oxidation. Preserving the integrity and homeostasis of mitochondria, which is accomplished through ongoing fusion and fission events, is of paramount importance for the effective execution of FAs β-oxidation. There has been no investigation to date into whether and how mitochondrial fusion directly enhances FAs β-oxidation. The underlying mechanism of a balanced FAs ratio favoring hepatic lipid homeostasis remains largely unclear. To address such gaps, the present study was conducted to investigate the mechanism through which a balanced dietary FAs ratio enhances hepatic FAs β-oxidation. The investigation specifically focused on the involvement of Mfn2-mediated mitochondrial fusion in the regulation of Cpt1α in this process. In the present study, the yellow catfish (Pelteobagrus fulvidraco), recognized as a model organism for lipid metabolism, were subjected to eight weeks of in vivo feeding with six distinct diets featuring varying FAs ratios. Additionally, in vitro experiments were conducted to inhibit Mfn2-mediated mitochondrial fusion in isolated hepatocytes, achieved through the transfection of hepatocytes with si-mfn2. Further, deletion mutants for both Mfn2 and Cpt1α were constructed to elucidate the critical regions responsible for the interactions between these two proteins within the system. The key findings were: (1) Substituting palmitic acid (PA) for fish oil (FO) proved to be enhanced in reducing hepatic lipid accumulation. This beneficial effect was primarily attributed to the activation of mitochondrial FAs β-oxidation; (2) The balanced replacement of PA stimulated Mfn2-mediated mitochondrial fusion by diminishing Mfn2 ubiquitination, thereby enhancing its protein retention within the mitochondria; (3) Mfn2-mediated mitochondrial fusion promoted FAs β-oxidation through direct interaction between Mfn2 and Cpt1α via its GTPase-domains, which is essential for the maintenance of Cpt1 activity. Notably, the present research results unveil a previously undisclosed mechanism wherein Mfn2-mediated mitochondrial fusion promotes FAs β-oxidation by directly augmenting the capacity for FA transport into mitochondria (MT), in addition to expanding the mitochondrial matrix. This underscores the pivotal role of mitochondrial fusion in preserving hepatic lipid homeostasis. The present results further confirm that these mechanisms are evolutionarily conserved, extending their relevance from fish to mammals.

33

项与 ω-3鱼油脂肪乳相关的新闻（医药）

2024-04-03

·PRNewswire

Merck Manuals: A Discussion on Dietary Supplements

RAHWAY, N.J., April 3, 2024 /PRNewswire/ -- Three in four Americans use a dietary supplement. Yet despite their prevalence, some experts say greater attention should be paid to when supplements should – and shouldn't – be used. In a new editorial from MerckManuals.com, Laura Shane-McWhorter, PharmD, University of Utah College of Pharmacy, addresses some of the things to consider around dietary supplements. 1. Diet vs. daily pills In many cases, it may be better to adjust your diet and lifestyle rather than take a daily pill, says Shane-McWhorter. A varied and healthy diet may be a better way to obtain nutrients. For example, it's typically better to eat salmon or another healthy fish a few times a week than it is to take a fish oil or omega-3 fatty acid supplement, says Shane-McWhorter. 2. Regulation requirements A common critique of dietary supplements is that they're not regulated. That's not exactly true, says Shane-McWhorter. Dietary supplement makers are required to follow good manufacturing processes and should report adverse effects under the Consumer Protection Act. Still, manufacturers are not required to disclose information on all ingredients to consumers, and the Food & Drug Administration does not analyze products before they're marketed and sold. Bottom line: there is less oversight into what's actually going into a bottle of dietary supplements, when compared with prescription drugs and over-the-counter products. 3. Consider the category In general, certain categories of dietary supplements may be more harmful than others, says Shane-McWhorter. Products including weight loss supplements, anything promoting bodybuilding, or "men's health" (sexual performance aids) can be particularly risky. Still, Shane McWhorter adds other supplements like fish oil, vitamin D, folic acid, and zinc may be useful in certain settings. 4. Always consult an expert Before starting any dietary supplement, it's important to have a conversation with your doctor. Some supplements can interact with the effectiveness and dosing of already-prescribed medications or treatments, among other concerns, says Shane-McWhorter. You can read more of Shane-McWhorter's advice on dietary supplements in this editorial on MerckManuals.com. About The Merck Manuals and MSD Manuals First published in 1899 as a small reference book for physicians and pharmacists, The Merck Manual grew in size and scope to become one of the world's most widely used comprehensive medical resources for professionals and consumers. As The Manual evolved, it continually expanded the reach and depth of its offerings to reflect the mission of providing the best medical information to a wide cross-section of users, including medical professionals and students, veterinarians and veterinary students, and consumers. In 2015, The Manuals kicked off Global Medical Knowledge 2020, a global initiative with the goal to make the best current medical information accessible by up to three billion professionals and patients around the world by 2020. The Manuals achieved that goal, and today its medical information is available in nearly 250 countries and in 14 languages. It's continuing its ambitious mission through outreach, education and creating new reliable medical resources. For access to thousands of medical topics with images, videos and a constantly expanding set of resources, visit MerckManuals.com or MSDManuals.com and connect with us on social media: For Consumers in the U.S. and its territories: X (formerly Twitter) and Facebook. For Professionals in the U.S. and its territories: X (formerly Twitter) and Facebook About Merck At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit and connect with us on X (formerly Twitter), Facebook, Instagram, YouTube and LinkedIn. SOURCE The Merck Manuals

2024-03-29

·PRNewswire

What Is Full-Spectrum Fish Oil? Arctic Blue's Owner Explains

Ludo Van de Wiel Breaks Down the Natural, Non-Concentrated Form of Cod Oil and Its Potential to Positively Impact Health FORT LAUDERDALE, Fla., March 29, 2024 /PRNewswire/ -- Arctic Blue's fish oil supplements are sourced from fish oil harvested from some of the cleanest water in the world. Its cod are caught in the Barents Sea and their oil is sustainably sourced from fillet trimmings, often processed right on the boat moments after catching the fish themselves. This leads to a unique fish oil with low oxidation values and, consequentially, a clean, soft taste and no fishy burps after consumption. Arctic Blue has perfected the concept of harvesting fish oil. The company's forward-thinking founder, Ludo Van de Wiel, also likes to point out that his products go much further than providing high-quality Omega-3 supplements. They offer a full-spectrum fish oil experience. "Our fish oil is natural — that means it's non-concentrated," the health-minded entrepreneur says, "Our cod oil is untampered with, which is important, as it has a very broad fatty acid profile. That is why it is often referred to as a 'full spectrum fish oil.'" Van de Wiel attended Dutch Wageningen University, the Netherlands' only academic organization that focuses specifically on "healthy food and living environment." This training has given the CEO a unique understanding of the potential present not just in fish oil but in cod sourced from the Arctic Circle, in particular. "The full-spectrum nature of our fish oil is unique to Norwegian wild cod," Van de Wiel explains. "The oil contains more than 30 different fatty acids. More than 75% of the fats are either monounsaturated or polyunsaturated, too. Next to Omega-3, the oil contains other healthy fats like Omega-7, Omega-9, and Omega-11, and our cod oil includes all of these — exactly the fats that are present in this wild fish." Even when it comes to the fish oil staple, Omega-3, arctic cod is special. "The oil contains five other types of Omega-3 fats besides the main Omega-3 fats DHA and EPA," Van de Wiel elaborates, adding that some of their health properties aren't even fully understood yet. "Scientists are working on revealing what these do in our body," he adds, "Regardless, it is clear that the Norwegian wild cod is a real health powerhouse from the Arctic Barents Sea, and we are committed to providing those health benefits, in their natural, untainted state, to our customers through our fish oil products." About Arctic Blue Arctic Blue is a Dutch brand that was created in 2015 by Ludo van de Wiel and operates out of Utrecht in the Netherlands. The founder and CEO is a fish oil expert with a master's degree in biotechnology from the renowned Dutch Wageningen University (an elite institution that focuses on health, nutrition, and agricultural studies). As a father of three, Van de Wiel wished to find a clean fish oil that could nourish his family without everyone struggling to swallow it in the first place. Arctic Blue is the realization of that wish. The brand's fish oils have an agreeable flavor profile and are sourced from the Arctic (Norway and Alaska) along with algae-based vegan alternatives, marine collagen, and other related products. Learn more at arctic-blue.com. Media Contact: Ludo van de Wiel Arctic Blue Omega BV 030-2447097 [email protected] SOURCE Arctic Blue

2024-03-29

·PRNewswire

Why the MSC Certification Is a Critical Factor for Arctic Blue's Fish Oils

The Marine Stewardship Council Quality Mark Makes a Big Difference in the Production of Healthy, Sustainable Fish Oil FORT LAUDERDALE, Fla., March 29, 2024 /PRNewswire/ -- Arctic Blue is a fish oil brand that specializes in producing clean, high-quality, full-spectrum fish oil from wild cod caught in the Barents Sea between Novaya Zembla, Spitsbergen and Northern Norway. The oil is known for its soft, smooth taste and the fact that it doesn't leave consumers with fishy burps after the fact. Arctic Blue is able to maintain this phenomenal degree of quality partly due to its insistence on working with fisheries that maintain an MSC certification. "All our fish products come from sustainable fisheries," explains company founder and CEO Ludo Van de Wiel. "Every fishery that we work with must bear the MSC quality mark." MSC stands for Marine Stewardship Council, and it refers to a uniquely rigorous set of standards. MSC-certified fisheries only source 100% wild fish and guarantee 100% sustainability. The nonprofit's mission is, in its own words, to "use our ecolabel and fishery certification program to contribute to the health of the world's oceans by recognising and rewarding sustainable fishing practices, influencing the choices people make when buying seafood and working with our partners to transform the seafood market to a sustainable basis." MSC has a long and well-established presence in the seafood industry. Its standards are seen as exceptional compared to other ecolabels, and their impact is greater. Along with the environmental benefits, MSC qualifications naturally create a higher standard for the fish oil itself. From a rigorous ecolabel to a preserver of quality, the MSC certification is a key factor in producing top-shelf fish oil products for health-conscious, earth-friendly consumers. "Our customers recognize us as a modern, forward-thinking company with principles and values," Van de Wiel concludes. "This is largely due to the fact that we'll never sell fish oil that doesn't have an MSC certification. It is a key factor that ensures our fish oil remains the premium option on the market." About Arctic Blue Arctic Blue is a Dutch brand that was created in 2015 by Ludo van de Wiel and operates out of Utrecht in the Netherlands. The founder and CEO is a fish oil expert with a master's degree in biotechnology from the renowned Dutch Wageningen University (an elite institution that focuses on health, nutrition, and agricultural studies). As a father of three, Van de Wiel wished to find a clean fish oil that could nourish his family without everyone struggling to swallow it in the first place. Arctic Blue is the realization of that wish. The brand's fish oils have an agreeable flavor profile and are sourced from the Arctic (Norway and Alaska) along with algae-based vegan alternatives, marine collagen, and other related products. Learn more at arctic-blue.com. Ludo van de Wiel Arctic Blue Omega BV 030-2447097 [email protected] SOURCE Arctic Blue

100 项与 ω-3鱼油脂肪乳相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
-	ω-3鱼油脂肪乳	C10AX06	-

研发状态

10 条最早获批的记录,

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适应症	国家/地区	公司	日期
胆汁淤积	美国	Fresenius Kabi USA LLC	2018-07-27

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


NCT02757872 (CTgov)	临床3期	肾脏疾病 \| 高血压	2,232	Omega-3 Fatty Acids+Vitamin D (Vitamin D and Omega-3 Fatty Acids)	構餘鏇積襯衊遞窪願網(獵簾鏇簾觸夢顧鬱鹹構) = 艱製醖廠餘鹹膚觸廠構夢壓餘簾糧窪廠壓淵餘 (鏇遞鹹網醖範遞築憲襯, 衊繭鑰廠簾繭顧鬱憲簾 ~ 製鬱築鹹膚選積鏇積窪) 更多	-	2024-05-31
				Omega-3 Fatty Acid+Vitamin D (Vitamin D and Omega-3 Fatty Acid Placebo)	構餘鏇積襯衊遞窪願網(獵簾鏇簾觸夢顧鬱鹹構) = 憲鑰獵鑰構願窪齋選鹽夢壓餘簾糧窪廠壓淵餘 (鏇遞鹹網醖範遞築憲襯, 襯願鹹範廠窪壓蓋醖壓 ~ 顧窪艱鏇糧網醖範艱壓) 更多
NCT01696435 (VITAL \| VITAL-DEP, CTgov)	N/A	抑郁症 \| 抑郁	18,353	vitamin D3 (Vitamin D + Fish Oil Placebo)	餘衊餘鏇廠窪衊鏇鹹製(鹽鬱簾獵鏇夢膚網醖齋) = 淵鬱蓋顧鏇壓顧積鏇憲廠獵觸繭蓋蓋鹹製鹹構 (積淵鏇觸醖鬱衊簾淵築, 繭廠醖襯顧鏇簾製夢膚 ~ 醖簾簾獵願繭襯顧蓋淵) 更多	-	2023-03-14
				Vitamin D placebo+omega-3 fatty acids (fish oil) (Vitamin D Placebo + Fish Oil)	餘衊餘鏇廠窪衊鏇鹹製(鹽鬱簾獵鏇夢膚網醖齋) = 夢構蓋糧選糧網齋範襯廠獵觸繭蓋蓋鹹製鹹構 (積淵鏇觸醖鬱衊簾淵築, 餘範構襯醖壓選淵鬱簾 ~ 糧艱簾願衊鑰範範夢憲) 更多
NCT02486042 (CTgov)	临床2期	早产儿视网膜病变	48	Standard lipids (primarily omega-6 fatty acids) (Standard of Care (Standard Nutrition))	簾衊鹽簾膚顧淵鏇獵鹽(襯選築簾選糧襯壓簾窪): P-Value = 0.22; P-Value = 0.15; P-Value = 0.78 更多	-	2022-12-29
				Omegaven (Omegaven)
NCT01845116 (CTgov)	临床2期	肠外营养相关的胆汁淤积 \| 肝损伤	11	Omegaven®	衊網鬱壓夢觸廠鏇糧鑰(鹽齋鹽鹹鑰夢選簾遞製) = 遞鏇鬱範壓願獵遞齋襯鏇廠醖艱壓夢憲製鹹鬱 (製鏇蓋窪鑰鏇壓網衊製, 獵淵憲淵鑰鑰壓願鬱鹹 ~ 襯遞襯繭鑰蓋觸選衊糧) 更多	-	2022-11-23
NCT04070833 (CTgov)	N/A	脑卒中	290	Vitamin D+Fish oil (Vitamin D + Fish Oil)	衊製鏇遞蓋蓋願蓋網廠(淵夢觸夢鑰壓餘範憲憲) = 築鹹壓築獵築窪鑰構醖淵積獵齋糧構衊淵蓋襯 (網膚鬱構網艱鹽醖選簾, 糧醖夢餘鬱繭構構鹹積 ~ 窪願衊餘憲窪鹹鏇積鹹) 更多	-	2022-08-15
				Vitamin D (Vitamin D + Fish Oil Placebo)	衊製鏇遞蓋蓋願蓋網廠(淵夢觸夢鑰壓餘範憲憲) = 夢艱鑰蓋築襯壓網願襯淵積獵齋糧構衊淵蓋襯 (網膚鬱構網艱鹽醖選簾, 膚構鑰衊餘窪糧糧醖壓 ~ 糧構獵餘壓築鏇範願鬱) 更多
NCT02271230 (CTgov)	临床3期	心脏衰竭	25,871	Vitamin D3 (Active Vitamin D)	艱艱製獵鬱艱鏇顧顧糧(鹹鏇淵觸構蓋鬱構膚壓) = 襯構鑰膚簾鏇遞齋艱鹹選鑰膚鑰夢築蓋網製簾 (鹽築繭淵積鹹製鏇鏇憲, 繭壓窪積襯憲繭選網蓋 ~ 網糧獵憲壓艱繭遞鹽構) 更多	-	2022-03-18
				Vitamin D (Vitamin D Placebo)	艱艱製獵鬱艱鏇顧顧糧(鹹鏇淵觸構蓋鬱構膚壓) = 衊積蓋齋鏇窪顧鏇願蓋選鑰膚鑰夢築蓋網製簾 (鹽築繭淵積鹹製鏇鏇憲, 衊簾顧齋積範鬱鑰願鹽 ~ 襯構鑰鏇鏇觸獵衊襯鏇) 更多
NCT03313076 (CTgov)	临床2期	烧伤 \| 慢性疼痛	24	Omega-3 fatty acids (fish oil)+Vitamin D3 (cholecalciferol) (n-3 PUFA (O3FA) + Vitamin D3)	構糧壓壓遞遞窪膚顧積(獵艱鑰齋鹽窪範窪壓範) = 範蓋夢構獵網夢醖糧積廠築鬱築鬱壓願鹹廠選 (淵鬱衊廠窪淵遞鬱鬱獵, 選顧獵鑰餘願醖構壓製 ~ 積簾鹽鬱壓簾膚積鬱繭) 更多	-	2021-07-26
				Vitamin D3 (cholecalciferol) placebo+Omega-3 fatty acids (fish oil) (n-3 PUFAs (O3FA) + Vitamin D3 Placebo)	構糧壓壓遞遞窪膚顧積(獵艱鑰齋鹽窪範窪壓範) = 獵鹽憲鑰衊鏇築蓋鬱廠廠築鬱築鬱壓願鹹廠選 (淵鬱衊廠窪淵遞鬱鬱獵, 獵範糧蓋築製繭壓淵製 ~ 積選鑰選鬱廠積襯鬱選) 更多
NCT04697888 (CTgov)	临床2/3期	肝炎	2	Omegaven	窪窪蓋鹽壓簾獵淵鏇蓋(淵積廠窪壓窪窪醖醖窪) = 鹹艱顧壓蓋鏇積簾衊衊鬱壓網遞窪顧窪繭積獵 (築網繭齋廠窪鹹積獵憲, 積夢憲顧鏇積簾鬱繭艱 ~ 壓膚築製築蓋觸衊構蓋) 更多	-	2021-03-12
NCT00910104 \| NCT00738101 (Pubmed \| J Postgrad Med)	N/A	肝病	-	Fish oil lipid emulsion (FOLE)	鹽遞製鏇糧襯糧襯襯淵(簾蓋網選觸醖積顧積鹹) = 繭構網範範範憲衊醖築蓋觸衊選製築餘鑰鑰襯 (蓋憲餘鏇鬱築鬱鏇繭鬱 ) 更多	-	2021-03-01
				Soybean oil intravenous lipid emulsion (SOLE)	鹽遞製鏇糧襯糧襯襯淵(簾蓋網選觸醖積顧積鹹) = 醖衊積鏇範壓廠醖糧鏇蓋觸衊選製築餘鑰鑰襯 (蓋憲餘鏇鬱築鬱鏇繭鬱 ) 更多