别名 Benign Supratentorial Neoplasm、Benign Supratentorial Neoplasms、Benign Supratentorial Tumor + [37] |
简介 Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation. |
作用机制 FOLR1激动剂 [+2] |
最高研发阶段批准上市 |
首次获批国家/地区 美国 |
首次获批日期2021-11-29 |
靶点 |
作用机制 PD-1抑制剂 |
在研适应症 |
最高研发阶段批准上市 |
首次获批国家/地区 日本 |
首次获批日期2014-07-04 |
开始日期2025-08-01 |
开始日期2025-05-07 |
开始日期2025-05-01 |
申办/合作机构- |