Delving into the Latest Updates on Universität Konstanz with Synapse

概览

疾病领域	数量

肿瘤	1
神经系统疾病	1

排名前五的药物类型	数量

小分子化药	1
化学药	1

排名前五的靶点	数量

KIF18A	1
PSMB8	1

关联

2

项与 Universität Konstanz 相关的药物

BTB-1

靶点

KIF18A

作用机制

KIF18A抑制剂

在研机构

Universität Konstanz

原研机构

Universität Konstanz

在研适应症-

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

PR-957

靶点

PSMB8

作用机制

PSMB8抑制剂

在研机构

Universität Konstanz [+1]

原研机构

Proteolix, Inc.

在研适应症

去势抵抗性前列腺癌 [+2]

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

14

项与 Universität Konstanz 相关的临床试验

DRKS00035990

/ SuspendedN/AIIT

Therapeutic alliance research utilizing physiologic synchrony in therapy - TRUST

开始日期2025-04-01

申办/合作机构

Universität Konstanz

DRKS00034963

/ RecruitingN/AIIT

A Therapist Guided Online-Intervention for Children with Avoidant/Restrictive Food Intake Disorder and Their Caregivers

开始日期2024-10-07

申办/合作机构

Universität Konstanz

DRKS00033410

/ SuspendedN/AIIT

Effect of a stepped care trauma rehabilitation program for refugees in Germany: A naturalistic parallel group trial with post-implementation randomization

开始日期2024-02-12

申办/合作机构

Universität Konstanz

100 项与 Universität Konstanz 相关的临床结果

登录后查看更多信息

0 项与 Universität Konstanz 相关的专利（医药）

登录后查看更多信息

24,810

项与 Universität Konstanz 相关的文献（医药）

2025-12-01·Current Neurology and Neuroscience Reports

Apraxia: From Neuroanatomical Pathways to Clinical Manifestations

Review

作者: Lorentz, Lukas ; Binkofski, Ferdinand ; Stoll, Sarah ; Randerath, Jennifer

AbstractPurpose of ReviewApraxia typically involves impairments in gesture production and tool use, affecting daily life activities. This article reviews current conceptualizations and developments in diagnostic and therapy.Recent FindingsApraxia has been studied in various neurological conditions, particularly stroke and dementia, but recent studies show gesturing deficits in psychiatric populations as well. Promising results have emerged from integrative treatment approaches involving intensive practice of gestures or daily activities. However, several reviews have noted the only marginal progress in apraxia therapy research despite new technologies, like virtual reality and brain stimulation, offering fresh opportunities for assessment and therapy.SummaryAdvances in lesion-symptom mapping and connectivity analyses led to more detailed neuroanatomical models emphasizing parallel and gradual processing. These models facilitate the understanding of underlying mechanisms of motor cognitive performance and its decline. Finally, the digital era prompts the need to study digital tool use in apraxia, with initial efforts underway.

2025-07-03·Communications in Algebra

On the ( S ₂ )-condition of edge rings for cactus graphs

作者: Shibu Deepthi, Nayana ; Dinu, Rodica

2025-07-01·Psychoneuroendocrinology

The role of "Social" in the TSST: Social support and social motives partly moderate psychobiological stress responses in addition to biological sex

Article

作者: Zimanyi, Zsuzsanna ; Schüler, Julia ; Stoffel, Martin ; Radtke, Vanessa ; Ditzen, Beate

Prior research has highlighted sex differences in psychobiological stress responses during the Trier Social Stress Test (TSST). This study expands on these findings by exploring how social motives (affiliation and power motives) and social support, as direct predictors and in interaction with biological sex, influence stress responses and reproductive hormones. A sample of 204 participants (108 women, 96 men) underwent the TSST, with social support being manipulated. The biological and psychological responses followed patterns previously documented in the literature. Linear mixed-effect models indicated that biological sex moderated the trajectories of RMSSD, testosterone, progesterone, and well-being across the TSST phases. Additionally, cortisol responses were more pronounced in men, particularly those with strong power motives. Participants receiving social support exhibited lower estradiol levels during the TSST recovery phase compared to the control group. These findings suggest that the impacts of social stress are shaped by complex interactions between biological and social factors, which could be considered in tailored stress interventions.

100 项与 Universität Konstanz 相关的药物交易

登录后查看更多信息

100 项与 Universität Konstanz 相关的转化医学

登录后查看更多信息