Delving into the Latest Updates on Shahid Chamran University of Ahvaz with Synapse

概览

疾病领域	数量

内分泌与代谢疾病	1
免疫系统疾病	1
神经系统疾病	1
肿瘤	1

排名前五的药物类型	数量

小分子化药	1

排名前五的靶点	数量

Nrf2 x STAT3	1

关联

1

项与 Shahid Chamran University of Ahvaz 相关的药物

Dimethyl itaconate

二甲酯衣康酸

靶点

Nrf2 x STAT3

作用机制

Nrf2调节剂 [+1]

在研机构

天津医科大学 [+2]

原研机构-

在研适应症

多囊卵巢综合征 [+3]

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

17

项与 Shahid Chamran University of Ahvaz 相关的临床试验

IRCT20240222061082N1

/ Recruiting临床3期IIT

The Effect of Combined Ointment of Alpha-Pinene and Frankincense in Rheumatoid Arthritis on Reducing Pain in Osteoarthritis

开始日期2024-03-10

申办/合作机构

Shahid Chamran University of Ahvaz

IRCT20230709058725N1

/ CompletedN/AIIT

comparison of the Effectiveness of transition to parenthood programs the Family Foundation(FF) with Couples Care for Parents(CCP) on subjective well-being, marital conflict, and marital satisfaction new parents.

开始日期2023-11-05

申办/合作机构

Shahid Chamran University of Ahvaz

IRCT20231013059706N1

/ RecruitingN/AIIT

Developing an educational program based on psychological empowerment and comparing its effectiveness with cognitive behavioral therapy on psychological flexibility, academic hope and life satisfaction of adolescents

开始日期2023-10-23

申办/合作机构

Shahid Chamran University of Ahvaz

100 项与 Shahid Chamran University of Ahvaz 相关的临床结果

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0 项与 Shahid Chamran University of Ahvaz 相关的专利（医药）

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9,110

项与 Shahid Chamran University of Ahvaz 相关的文献（医药）

2025-05-01·Journal of Molecular Graphics and Modelling

Nanoring interactions with bio-relevant molecule: A quantum chemical approach to C18 and B9N9 systems

Article

作者: Vishwkarma, A K ; Shakerzadeh, E ; Adam, J ; Garai, S ; Vetrivelan, V ; Pathak, A ; Yadav, T ; Goswami, S

This study investigates the interaction of a synthetic bio-relevant molecule with C₁₈ and B₉N₉ nanorings, exploring their potential applications in sensing and drug delivery. Employing Density Functional Theory (DFT) at the ωB97XD level with the 6-31G(d,p) basis set, we computed the adsorption and electronic properties of the resulting nanocomplexes. A total of ten distinct configurations were identified for the interactions, with adsorption energies ranging from -6.75 to -12.62 kcal/mol for the C₁₈@target molecule and -9.01 to -18.46 kcal/mol for the B₉N₉@target molecule. Notably, alterations in the energy gap between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) upon interaction suggest an enhancement in electrical conductivity. The effect of aqueous media was also examined, revealing an increase of approximately 2.0 Debye in the dipole moments of the most stable nanocomplexes. Additional analyses, including reduced density gradient (RDG), UV-Vis spectroscopy, and Quantum Theory of Atoms in Molecules (QTAIM), were conducted in both gas and aqueous phases. Our findings indicate that C₁₈ and B₉N₉ nanorings exhibit significant promise as candidates for drug delivery and sensing applications, particularly due to their enhanced electronic properties upon interaction with the bio-relevant molecule.

2025-05-01·Journal of Molecular Graphics and Modelling

Borophene based quasi planar nanocluster for ethanol, isobutanol, and acetone sensing: A first principle study

Article

作者: Ajalli, Nima ; Rezaie, Forough ; Kamalinahad, Saeedeh ; Azamat, Jafar

In this study, the need for efficient detection of volatile organic compounds (VOCs) in environmental monitoring, industrial safety, is addressed by investigating borophene-based B36 nanoclusters as gas sensors. Density functional theory (DFT) calculations were employed to examine the adsorption behavior of ethanol, isobutanol, and acetone on B₃₆ surfaces, with a focus on vibrational modes, reactivity, and adsorption energies. It was found that acetone exhibits the strongest interaction with pristine B₃₆, indicating its potential for robust sensing applications. To further enhance sensor performance, the effects of doping B₃₆ with nickel (Ni) and iron (Fe) atoms were explored. The electronic structure was significantly modified in Fe@B₃₆, showing strong chemisorption properties, while Ni@B₃₆ showed less impact, serving as a counterexample. Additionally, conductivity, recovery time, and global reactivity parameters were analyzed, providing insights into the sensor's functionality. It is suggested that B₃₆ nanoclusters, particularly Fe-doped systems, offer promising prospects for future gas sensor development and VOC detection.

2025-04-01·Veterinary Research Communications

Evaluation of sectional anatomic, micro-computed tomographic, and magnetic resonance imaging features of the thorax in Syrian hamsters (Mesocricetus auratus)

Article

作者: Hanafi, Mohammad Ghasem ; Nourinezhad, Jamal ; Moarabi, Abdolvahed ; Homayonnezhad, Zahra ; Janeczek, Maciej

Clinically, the rodent thorax is important because of the variety of problems that may affect the heart, lungs, and other thoracic structures. Syrian hamsters are the most common pet and experimental hamster species. Sectional imaging of small mammals is widely increasing in use for clinical and research settings; however, no reports on the thoracic sectional imaging anatomy in this species have been made. Therefore, this study aimed at evaluating micro-computed tomography (MCT), magnetic resonance image (MRI), and gross sections of the Syrian hamster thorax. Eight healthy adult male and female Syrian hamsters were examined. Anesthetized hamsters were evaluated by MCT and 3 Tesla MRI. After imaging, the frozen slab sections were photographed, and identified anatomic structures were matched with structures on corresponding MCT and/or MRI images. Clinically relevant anatomic features of the Syrian hamster thorax that were identified on transverse and sagittal anatomic sections could be discerned on the corresponding MCT and MRI scans. The three matched images were exhibited the following features: (1) the narrow thoracic cavity and small lung space, (2) the heart positioning ventral and medial to lung, (3) heart ventricles locating towards the left side, and (4) parallel cardiac position relative to the sternum. The obtained results were similar to those have only been reported in rabbits, regardless of heart orientation and lung lobe covering the heart. The results of this study support the use of MCT and MRI as diagnostic tools in Syrian hamsters and provide reference values for the clinically relevant anatomic structures of thorax.

100 项与 Shahid Chamran University of Ahvaz 相关的药物交易

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100 项与 Shahid Chamran University of Ahvaz 相关的转化医学

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