Dietary manipulations are crucial for enhancing rabbit behavior and performanceAddn. of Berberine-loaded chitosan nanoparticles BER-CNPs to fattened rabbit diets has been shown to alleviate the adverse effects of heat stress.BER-CNPs have been found to improve growth performance, feed efficiency, liver functions, immunity and redox balanceBER-CNPs have been observed to reduce the levels of IL-4, TNF-α, IFN-γ, Amyloid A, and NF-κ B while increasing the levels of NO and LZM