Avacta Ltd.

A review.The 1st part of this article introduced the basic features of Raman spectroscopy and presented some examples of its application in the pharmaceutical industry.This second part focuses on the technique's application as a PAT tool within the pharmaceutical manufacturing environment.FDA's PAT initiative has provided motivation to explore the application of 'new' anal. technologies to the pharmaceutical manufacturing process and Raman spectroscopy shows great promise.The strengths and weaknesses of the technique as a potential PAT tool are discussed together with some examples of how this works in practice in a pharmaceutical manufacturing environment.

A review.The aim of this article is to familiarize the reader with the basic principals of Raman spectroscopy, with a particular focus on its practical application.By highlighting some of the strengths and weaknesses of the technique, it is hoped the reader will become better equipped to assess what the technique has to offer in their particular application and then begin to think how it may be implemented.Some potential applications to pharmaceutical anal. are also reviewed.