Novel Rheumatoid Arthritis drugs succeed in the clinical trials: A status report by DelveInsight

2021-03-19

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Los Angeles, USA , March 18, 2021 (GLOBE NEWSWIRE) -- Novel Rheumatoid Arthritis drugs succeed in the clinical trials: A status report by DelveInsight The Rheumatoid Arthritis Pipeline is robust as various companies such as Ablynx, Cyxone, Oryn Therapeutics, Gilead Sciences, Sorrento Therapeutics, Genor Biopharma, Kang Stem Biotech, Celltex Therapeutics, Bristol-Myers Squibb, Arthrogen, Baylx, R-Pharm, Astellas Pharma, Sanofi, Amgen, I-MAB Biopharma, Taisho Pharmaceutical, Novartis, Kymera Therapeutics, UCB, and many others are developing therapies to influence treatment scenarios. DelveInsight’s “Rheumatoid Arthritis Pipeline Insight'' report provides comprehensive insights about 200+ companies and 250+ pipeline drugs in the Rheumatoid Arthritis pipeline landscapes. It comprises Rheumatoid Arthritis pipeline drug profiles, including clinical and non-clinical stage products. It also includes the Rheumatoid Arthritis therapeutics assessment by product type, stage, route of administration, and molecule type and further highlights the inactive Rheumatoid Arthritis pipeline products. Some of the significant features of the Rheumatoid Arthritis Pipeline Report Get an overview of pipeline landscape @ Rheumatoid Arthritis Clinical Trial AnalysisRheumatoid Arthritis is an autoimmune disease, which causes pain, swelling, and stiffness in the joints and usually affects the hands, feet and wrists.Rheumatoid Arthritis diagnosis is difficult since many conditions cause joint stiffness and inflammation, and there is no definitive test for the condition. Rheumatoid Arthritis treatment can help lessen inflammation in the joints, relieve pain, prevent/ slow down joint damage, reduce disability. However, there is no cure for the condition. But there have been several clinical trials that have shown potential treatments. Rheumatoid Arthritis Emerging Drugs Ozoralizumab (ATN-103) is a humanised monoclonal antibody designed to treat inflammatory diseases and is developed by Ablynx. It is a trivalent, bispecific nanobody that potently neutralises Tumour Necrosis Factor (TNF) and binds to human serum albumin to increase its in vivo half-life. It consists of two anti-tumour necrosis factor-α (TNF-α) nanobodies (TR2) and one albumin-binding nanobody (ARI) with an MW~45 kDa which was successfully developed preclinically. In a phase I study, ATN-103 showed good tolerability and subsequently was licensed to Pfizer. Taisho Pharmaceutical is carrying out the Phase III trial.Research and DevelopmentPhase III NCT04077567: Taisho Pharmaceutical initiated an extension study of TS-152 in subjects with Rheumatoid Arthritis in October 2019. The purpose of this trial is to assess the long-term safety and efficacy of TS-152 in subjects with Rheumatoid Arthritis who have finished the previous study (TS152-3000-JA study or TS152-3001-JA study). The trial is currently active but not recruiting with an estimated enrollment of 401 participants and is anticipated to get completed by December 2022.Results Ablynx announced that its anti-TNFα Nanobody, ozoralizumab (ATN-103), for the treatment of the inflammatory diseases, displayed excellent safety and efficacy results in the 48-week open-label extension (OLE) study of the globally and Japanese Phase II trials in the treatment of patients with Rheumatoid Arthritis who have an insufficient response to methotrexate alone.For further product profiles, request @ Rheumatoid Arthritis Pipeline Therapeutics Scope of Rheumatoid Arthritis Pipeline Drug Insight Key Questions regarding Current Rheumatoid Arthritis Treatment Landscape and Emerging Therapies Answered in the Pipeline Report Table of Contents Get a customized pipeline report @ Rheumatoid Arthritis Drugs Pipeline Report Related Reports DelveInsight's Rheumatoid Arthritis (RA) - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and an in-depth understanding of the disease, historical, and forecasted epidemiology. DelveInsight's Rheumatoid Arthritis (RA) - Epidemiology Forecast 2030 report delivers an in-depth understanding of the disease, historical, and forecasted epidemiology of Rheumatoid Arthritis. DelveInsight's Temporomandibular Disorders- Market Insights, Epidemiology, and Market Forecast - 2030 report provides a detailed overview, historical and forecasted epidemiology. DelveInsight's Ocular Hypertension - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and an in-depth understanding of historical and forecasted epidemiology. DelveInsight's DDR Defective Tumors - Market Insights, Epidemiology, and Market Forecast - 2030 report provides a detailed overview, historical and forecasted epidemiology. DelveInsight's Anorexia - Market Insights, Epidemiology, and Market Forecast - 2030 report provides a detailed overview, historical and forecasted epidemiology. DelveInsight's Chronic Cough - Market Insights, Epidemiology, and Market Forecast - 2030 report provides a detailed overview, historical and forecasted epidemiology. DelveInsight's Hairy Cell Leukemia (HCL) - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and an in-depth understanding of historical and forecasted epidemiology. About DelveInsightDelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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