DUBLIN--(BUSINESS WIRE)--The "Microbiome-Targeting Therapeutics in Infectious Diseases - Thematic Research" report has been added to ResearchAndMarkets.com's offering. Microbiome-targeting drugs aim to alter the microbial composition of the gut through the administration of live microbes with the intention of regulating the human microbiome composition in a beneficial way that may effectively treat a wide variety of infectious diseases (ID) ranging from cancer to psychiatric disorders, and even COVID-19. There are currently 23 drugs in clinical development that target the microbiome for ID indications in the 7MM. Ten out of the 23 drugs (43%) are in in clinical development for Clostridioides difficile infections (CDI). Currently, only one successful microbiome-based intervention, fecal microbiota transplantation (FMT), is used in clinical practice to treat CDI. Rebiotix Inc currently holds the most potential in the microbiome space for infectious diseases, with two drug candidates under development across 4 different indications. With most of the pipeline dominated by gastrointestinal (GI) tract infections, other indications remain a largely untapped market in the microbiome space, leaving ample opportunities for companies to invest in this novel therapeutic area. What impact will late-stage pipeline agents have on the market? Which class of IO drugs will have the highest peak sales, and why?
What are the current unmet needs and which pipeline drugs or strategies are positioned to counter these unmet needs? What are the opportunities for R&D in the microbiome-targeting in ID space?
How is the field of microbiome-targeting therapies in ID going to move forward? Which indications are the most promising for combination therapy? What is the regulatory landscape for live biotherapeutic products (LBP) in the US and 5EU?
What is the current and future outlook for microbiome-targeting therapeutics according to KOLs?
3.1. What is the Microbiome?
3.2. Microbiome of the Gut
3.3. Microbiome of the Respiratory Tract
3.4. Microbiome of the Skin
5.1. Microbiome Value Chain
6.1. Fecal Microbiota Transplants
6.2. Fecal Microbiota Transplants - Clinical Trial Mapping in the 7MM
6.3. Current Therapies - KOL Perspectives
7.2. Clinical Trials - Pipeline Microbiome Targeting Drugs
7.3. Overview of Phase III Pipeline Drugs Targeting the Microbiome for ID in the 7MM 7.4. Late-Stage Pipeline Products - FDA Review Designations
7.5. Pipeline Therapies - KOL Perspectives
8.1. Anticipated Key Launch Dates - Phase III Pipeline Agents
8.4. Market Outlook for Infant Bacterial Therapeutics' IBP-9414 9. Opportunities, Challenges, and Unmet Needs
9.2. Unmet Needs - KOL Perspectives
9.3. Challenges in Immuno-oncology Clinical Trials - KOLs Perspective
11. Drug Development Thematic Scorecard
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