Immunovant is realigning its clinical development plans, prioritising the next-generation FcRn inhibitorFcRn inhibitor IMVT-1402 as its lead asset over previously touted batoclimab. This decision has led to a postponement of clinical readouts for batoclimab, as the company doubles down on the perceived potential of IMVT-1402 across multiple autoantibody-driven indications.
In a corporate update, Immunovant said it is looking to start four to five potentially registrational studies for IMVT-1402 by the end of March 2025, spanning therapeutic areas such as endocrinology and neurology. By the end of 2026, it hopes to raise that number to a total of 10 indications.
"We are very excited about the immunology market evolution that we believe positions the anti-FcRn mechanism to be the leading therapeutic class across a broad range of autoantibody-driven indications," said CEO Pete Salzmann. "Within the class, we see tremendous opportunity for IMVT-1402, which we believe has a combination of potentially best-in-class features not seen with any other FcRn inhibitorFcRn inhibitor."