A comparative clinical study to evaluate the efficacy of bala shatavari ksheeradhara followed by ashwagandha churna and bala-shatavari ksheeradhara followed by vacha churna in chittodvega vis-à-vis adjustment disorder - NIL

开始日期2025-09-23

申办/合作机构-

CTRI/2024/07/071655 / Not yet recruiting临床3期

Evaluation of the comparative efficacy of Vidarikand vati (Pueraria tuberosa DC) vs. Ashwagandha vati (Withania somnifera Linn) in Karshya (underweight): Randomized controlled trial. - A randomised controlled experiment was conducted to assess the comparative effectiveness of Vidarikand vati and Ashwagandha vati in treating karshya (underweight).

开始日期2025-04-08

申办/合作机构-

CTRI/2024/01/061826 / Not yet recruiting临床2/3期IIT

A randomized controlled clinical study of Gambhariphal granules and Ashwagandha granules in the management of karshya(underweight) in children of age group between 6-12 years. - NIL

开始日期2024-12-15

申办/合作机构-

100 项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的临床结果

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100 项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的转化医学

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100 项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的专利（医药）

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项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的文献（医药）

2024-03-01·Cureus

Painless Thyroiditis by Withania somnifera (Ashwagandha)

作者: Hamada, Hina ; Azuma, Shin-Ichiro ; Hayashi, Koji ; Hayashi, Maho

The Withania somnifera, also called Ashwagandha, is available everywhere in the world. We present a rare case of thyrotoxicosis following Ashwagandha administration, specifically painless thyroiditis (PT) in this report. The patient was a 47-year-old previously healthy Japanese man, who started taking Ashwagandha two months before his first visit to our hospital. He visited our hospital for typical thyrotoxicosis symptoms like a sense of fatigue, fever at night, and weight loss followed by diarrhea and headache. Blood tests disclosed thyrotoxicosis. Thyroid ultrasonography showed internal echo heterogeneity and no increase in blood flow. Thyroid scintigraphy revealed a deficiency in thyroid uptake. Based on these findings, he was diagnosed as PT. After stopping the administration of Ashwagandha, both his symptoms and serum thyroid markers were improved. This report may spark important debate about whether ashwagandha is safe among healthy people, especially in thyroid toxicity.

2023-11-01·Journal of Ayurveda and integrative medicine

Effects of Withania somnifera root extract serum application on hair health in healthy adults: A prospective, double-blind, randomized, parallel, placebo-controlled study

Article

作者: Reddy, Venkateswar ; Yerram, Chinmai ; Jillella, Aditya

BACKGROUND:

Alopecia is a dermatological condition affecting genders, negatively impacting their personality and quality of life (QoL). The current approved entities are limited, inconsistently effective, and associated with negative side effects. To alleviate this issue, ayurvedic herbs such as Ashwagandha have being explored. As a result, this study was designed to evaluate the efficacy and safety of Ashwagandha (root extract) topical formulation (serum) on hair health in healthy adults.

METHODS:

In this prospective, double-blind, randomized, placebo controlled, two arm, parallel, comparative study, the effects of topical Ashwagandha on the hair health was evaluated. Healthy adults between 18 and 45 years with mild to moderate hair loss were randomized to either Ashwagandha (topical) or Placebo (topical) treatment. The participants were assessed at Day-1 and Day-75 for change in efficacy parameters, which included 60 Seconds Hair Comb, Trichoscan analysis, Hair Pull test, Investigator's Global Assessment (IGA) and QoL using Hair-specific Skindex-29.

RESULTS:

In the per protocol analysis of 61 participants, Ashwagandha group demonstrated significant reduction in hair shedding in the 60 Seconds Hair Comb test compared to Placebo at day 75. Similarly, Ashwagandha substantially enhanced hair density, growth, and thickness compared to the Placebo group (density = 7.3 vs. 2.8, P < 0.001; growth = 21.7 vs. 4.2, P < 0.001; thickness = 1.8 vs. 0.9, P < 0.001). In addition, Ashwagandha significantly improved QOL compared to placebo (Score = -17.3 vs. -6.1, P = 0.011).

CONCLUSION:

The study found that topical Ashwagandha (serum) improved hair growth and hair health indicators. Thus, it can be an effective and safer alternative for alopecia.

STUDY REGISTRATION:

CTRI, Number CTRI/2022/11/047539, Registered on: 23/11/2022.

2023-11-01·Journal of psychopharmacology (Oxford, England)

Exploring the efficacy and safety of a novel standardized ashwagandha (Withania somnifera) root extract (Witholytin®) in adults experiencing high stress and fatigue in a randomized, double-blind, placebo-controlled trial

Article

作者: Fairchild, Timothy J ; Lopresti, Adrian L ; Smith, Stephen J

Background::

Stress is a state of homeostasis in the body being challenged, resulting in a systemic response. It has become more prevalent in recent years and affects mental and physical health.

Aims::

Evaluate the effects of ashwagandha on stress, fatigue, and sex hormones in overweight or mildly obese men and women with self-reported stress and fatigue.

Methods::

Two-arm, parallel-group, 12-week, randomized, double-blind, placebo-controlled trial on overweight or mildly obese men and women aged 40–75 years, supplementing with 200 mg of an ashwagandha root extract (Witholytin®) twice daily.

Results/Outcomes::

Supplementation with ashwagandha was associated with a significant reduction in stress levels based on the Perceived Stress Scale (primary outcome); however, the improvements were not significantly different to the placebo group ( p = 0.867). Based on the Chalder Fatigue Scale, there was a statistically significant reduction in fatigue symptoms in the ashwagandha group compared to the placebo group ( p = 0.016), and participants taking ashwagandha also experienced a significant increase in heart rate variability ( p = 0.003). However, there were no significant between-group differences in other self-report outcome measures. In the men taking ashwagandha, there was a significant increase in the blood concentrations of free testosterone ( p = 0.048) and luteinizing hormone ( p = 0.002) compared to the placebo group.

Conclusions/Interpretation::

The results of this study suggest that in overweight middle-to-older age adults experiencing high stress and fatigue, compared to the placebo, ashwagandha did not have a significantly greater impact on perceived stress levels. However, based on secondary outcome measures, it may have anti-fatigue effects. This may be via its impact on the autonomic nervous system. However, further research is required to expand on these current findings.

项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的新闻（医药）

2024-07-29

·PRNewswire

Ayurveda Women's Health Market to Reach US$ 7.2 Billion by 2034, Driven by Growing Prevalence of Women's Health Issues and Enhanced Focus on Gut Health | TMR

The expansion of the Ayurvedic women's health industry is mostly due to the rise in the prevalence of women's health issues and the necessity to treat hormonal imbalances. WILMINGTON, Del., July 29, 2024 /PRNewswire/ -- The Ayurveda women's health market was projected to attain US$ 3.6 billion in 2023. It is likely to garner a 6.3% CAGR from 2024 to 2034, and by 2034, the market is expected to attain US$ 7.2 billion. Yoga poses, or asanas, are another aspect of Ayurvedic women's health practices that can help with conditions like menstrual cramps and back pain. They benefit women of all ages, but especially pregnant women, by improving posture, strength, and flexibility. Stress-relieving herbal tea brewed with chamomile and peppermint can be consumed. Fenugreek seeds can assist in increasing milk production, which is beneficial for nursing moms. As a result, the market value of Ayurveda for women's health is increasing due to growing knowledge of its benefits. Request for sample PDF copy of report: Key Findings of Market Report Ayurveda includes self-massage, or "Abhyanga," among its practices. The heated oil used here promotes better blood circulation and calms the nervous system. This is especially beneficial for menopausal ladies. The preservation of healthy skin and joint lubrication are the other benefits. Herbs like ashwagandha and asparagus are suggested in addition to meditation to promote hormonal balance. Turmeric and ginger can aid in the battle against inflammation and dyspepsia. Regarding the same, there are several Ayurvedic pills accessible. But before using Ayurvedic treatments, ladies should make sure they know what's in them. For example, certain Ayurvedic items may include lead or mercury, both of which are harmful to health. Furthermore, there are misconceptions about pregnant women taking Ayurvedic medications. These elements could eventually limit the market for Ayurvedic women's health. Market Trends for Ayurveda Women's Health Hormonal imbalances may lead to a wide range of health issues, including mood changes, weight gain, and perhaps even infertility. Ayurveda provides a comprehensive method for naturally achieving hormone balance. Hormonal imbalances can result from certain medical disorders, such as heavy menstrual bleeding, poor diet, and stress. According to Ayurveda, using herbs like ashwagandha, guduchi, and shatavari is beneficial for women's health. It suggests using panchakarma to assist the body rid itself of toxins, which can help balance hormones. Breathing techniques and meditation are also advised. Regular oil massage with Ayurvedic medicinal oils can assist with hormone balance, stress reduction, and improved circulation. The WHO estimates that 8–13% of women in the globe who are of reproductive age have PCOS. Thus, the need to adequately address the hormonal imbalance that is the primary cause of PCOS is driving the expansion of the Ayurvedic women's health industry. Ayurveda Women's Health Market Report Scope: Unlock Growth Potential in Your Industry! Download PDF Brochure: Global Market for Ayurveda Women's Health: Regional Outlook Various reasons propel the Ayurveda women's health market growth throughout the regions. These are: Asia Pacific held the greatest proportion of the Ayurvedic women's health market in 2023, according to the most recent research on the industry. Throughout the projection period, the area is anticipated to remain at the forefront in this respect. This is attributable to several awareness-raising initiatives on the use of Ayurveda for women's health treatments carried out by both governmental and non-governmental organizations in nations like China and India. The main players are also creating women's Ayurvedic food. Take Deep Ayurveda Healthcare Pvt., for example. Ltd. has introduced NariPunch, a superfood Ayurvedic for the wellness of women. Ayurveda Women's Health Market: Key Players By educating women in low- and middle-income areas about the value of their health, the major participants in the Ayurvedic women's health industry hope to increase the size of their clientele. The following companies are well-known participants in the ayurveda women's health market: The Himalaya Drug Company Dabur Patanjali Ayurved Limited Baidyanath Group Hamdard Laboratories (India) Vicco Laboratories Charak Pharma Pvt. Ltd. Sri Sri Tattva Zandu Pharma Works Ltd. Arya Vaidya Pharmacy (Coimbatore) Ltd. Key Developments Ayufy released its mobile app on the Play Store and App Store in February 2024. There are fifty Ayurvedic physicians on board. According to the firm, it is the first Ayurvedic start-up in India focused on helping women of all ages with their gynecological problems. Global Ayurveda Women's Health Market Segmentation Product Type - Herbal Supplements - Ayurvedic Medicines - Herbal Tea - Ayurvedic Oils and Balms Indication - Menstrual Disorders - Menopause Symptoms - Fertility Issues - Pregnancy Care - Others (Postpartum Care, etc.) Age Group - Adolescents - Adults - Elderly Women Distribution Channel - Online Retail - Specialty Stores - Pharmacies - Direct Sales - Others By Region - North America - Latin America - Europe - Asia Pacific - Middle East & Africa Buy this Premium Research Report: More Trending Reports by Transparency Market Research – Consumer Genomics Market - The global consumer genomics market was estimated to have acquired US$ 2.4 billion in 2021. It is anticipated to register a 22.3% CAGR from 2022 to 2032 and by 2032, the market is likely to gain US$ 21.2 billion. Acute Migraine Treatment Market - The global market for acute migraine treatment was estimated to be worth a market valuation of around US$ 2.1 billion in 2021. The market is anticipated to advance with a booming 15.1% CAGR from 2023 to 2031 and by 2031, the market is likely to gain US$ 7.9 billion. Biological Imaging Reagents Market is expected to grow at a CAGR of 5.4% from 2023 to 2031 and reach US$ 26.9 Bn by the end of 2031 About Transparency Market Research Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information. Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports. Contact: Transparency Market Research Inc. CORPORATE HEADQUARTER DOWNTOWN, 1000 N. West Street, Suite 1200, Wilmington, Delaware 19801 USA Tel: +1-518-618-1030 USA – Canada Toll Free: 866-552-3453 Website: Email: [email protected] Follow Us: LinkedIn | Twitter | Blog | YouTube Logo: SOURCE Transparency Market Research

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2024-03-25

·PRNewswire

KINDRA LAUNCHES FIRST-EVER COMPREHENSIVE VAGINAL HEALTH SYSTEM: THE DAILY V SYSTEM

Four-Part Daily Product Regimen Supports Vulvar and Vaginal Skin Health & Wellness NEW YORK, March 25, 2024 /PRNewswire/ -- Today, Kindra, the sex-positive vaginal health brand, announced the launch of the first-ever comprehensive vaginal health product system - the Daily V System. The 4-part daily regimen of Kindra products includes: Daily Vaginal Lotion, V Relief Serum, Soothe Bath Soak and the Core Supplement meant to support vulvar and vaginal skin for optimal vaginal health and sexual wellness. Continue Reading Kindra Daily V System This hormone-free system is designed to provide targeted relief and support for daily vulvar and vaginal health needs. Scientifically formulated with clinically-tested ingredients, the regimen is designed to enhance vaginal lubrication, increase libido, and alleviate symptoms such as dryness, itching, burning, stinging, and sensitivity. "At Kindra, we are dedicated to bringing women science-backed solutions that address their vaginal health," said Catherine Balsam-Schwaber, Kindra's CEO. "Our new Daily V System is designed to improve daily comfort and bring back pain-free sex." The Daily V System is gynaecologically tested, pH-balanced for intimate skin, clinically proven to be non-irritating & hypoallergenic, free of hormones, parabens, sulfates, or fragrances, safe to use with hormone therapy and vegan & certified cruelty-free. Kindra's products are recommended by 2,000+ OB/GYNs, urologists, pelvic health experts, and women's health providers. "As an OB/GYN and integrative medicine specialist, I'm thrilled about Kindra's innovative, targeted system for everyday vaginal health," said Dr. Suzanne Gilberg-Lenz, MD, FACOG, Board Certified OB/GYN and Kindra Medical Advisor. "These clinically-tested formulations are safe to use on their own, or as part of a hormone therapy regimen. The Daily V System provides daily comfort and hydration, while also enhancing intimacy. Your vaginal health matters, and this clean, easy-to-use system is a great option for anyone experiencing vulvovaginal dryness, burning, stinging or painful sex, whether due to hormonal fluctuations from oral contraceptive use, postpartum, or peri/menopause." As part of its launch of the Daily V System, Kindra has partnered with pelvic floor physical therapist Dr. Sara Reardon, known online as The Vagina Whisperer, on a video about the importance of a daily vaginal health regimen for long-term vulvovaginal health and comfort. The content is shared on The Vagina Whisperer and Kindra's Instagram pages. You can also find The Vagina Whisperer and Kindra on TikTok. "The Daily V System from Kindra [...] is the first ever doctor-approved hormone-free vaginal health regimen that helps provide game-changing relief from day 1," said Dr. Sara Reardon, PT, DPT, WCS, BCB-PMD, in the video. Results from Kindra customers on the Daily V System: 93% of women who used the Daily Vaginal Lotion daily for 3 days reported long-lasting hydration and 91% of women reported an improvement in the feeling of pain during sex after 14 days. 100% of women who used the V Relief Serum daily for 4 weeks reported improvement in the severity of vaginal discomfort or irritation. 100% of women who used Soothe reported meaningful improvement in vulvar and vaginal dryness. Core's hero ingredients support hydration from the inside out. Pycnogenol® is clinically-proven to increase hyaluronic acid by 44%, a key factor for deep skin hydration and moisture. Women who took Core daily for 8 weeks experienced a 46% decrease in vaginal dryness. Ashwagandha is clinically-proven to support healthy testosterone levels in women, a crucial hormone for libido, and for increased vaginal lubrication, arousal, and orgasm. The Daily V System is available for purchase on ourkindra.com. About Kindra Kindra is a breakthrough company dedicated to the well-being of vulvas and vaginas, building the much-needed category of scientifically-backed solutions, education, and community for women over 35 navigating vaginal health and sexual wellness. Kindra helps women prepare for, manage, and embrace their changing bodies and profound hormonal shifts, with products recommended by 2,000+ OB/GYNs, urologists, pelvic health experts, and sex therapists/educators. Through hormone-free, physician-backed, patent-pending solutions that target some of the most disruptive vaginal health symptoms, Kindra's community of women are finding relief and feeling empowered. For more information on Kindra, please visit: ourkindra.com Contact: Patricia Rappaport Civic Entertainment Group [email protected] SOURCE Kindra

临床结果

2024-03-21

·GlobeNewswire-Health Care

Evn Introduces Innovative CBD+THC Ashwagandha Gummies for Optimal Stress Adaptation and Recovery

NEW YORK, March 21, 2024 (GLOBE NEWSWIRE) -- Evn, a leader in hemp-derived cannabinoid products, is excited to announce the launch of its new product, Ashwagandha Gummies infused with CBD and THC, aimed at aiding stress adaptation. Crafted with the highest quality ingredients, Evn's Ashwagandha gummies combine the ancient wisdom of Ashwagandha with the modern benefits of cannabinoids. Every gummy is meticulously created from hemp-derived rosin, which ensures full legal compliance with less than 0.3% THC content, while also offering grounding effects of CBD. Key Features and Benefits: Synergistic Blend: The pairing of Ashwagandha with cannabinoids elevates the gummies' effectiveness, perfect for those seeking a natural way to manage stress and promote recovery.Legal and Safe: Using hemp-derived rosin, Evn ensures that all gummies comply with legal standards, providing a worry-free experience.Optimal Performance: Specifically formulated for individuals who aim to perform at their best, whether in day-to-day life or in athletic endeavors. Evn is determined to stay at the forefront of product innovation in the cannabinoid space. The company's focus remains steadfast on providing products that not only meet the legal requirements but exceed consumer expectations in terms of quality and efficacy. "In the rapidly evolving world of health and wellness, we recognize the power of combining traditional remedies with modern science. Our Ashwagandha gummies are a testimony to our commitment to innovation, wellness, and the overall health of our customers. We're not just creating products; we're enhancing lifestyles with every gummy we produce." – Josh Krumholz, CEO. The new Ashwagandha Gummies are now available for purchase directly from the Evn website. About Evn: Evn provides high-quality, hemp-derived products that are designed to help people live and excel in their daily lives. With an unwavering commitment to innovation, purity, and effectiveness, Evn continues to set the bar for industry excellence. Contact: info@evn-cbd.com A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/90104089-1ee6-4f2f-a257-0b2d44c062ee

100 项与 Ashwagandha(Sutter Fairfield Surgery Center) 相关的药物交易

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适应症	最高研发状态	国家/地区	公司	日期
精神分裂症	临床3期	美国	The Stanley Medical Research Institute	2018-12-01
睡眠异常	临床3期	美国	Loma Linda University	2017-10-05
应力性骨折	临床3期	美国	Loma Linda University	2017-10-05
肥胖	临床3期	美国	Loma Linda University	2017-10-05
精神疲劳	临床2期	美国	Sutter Health	2023-01-01
肿瘤	临床2期	美国	Sutter Health	2023-01-01
认知功能障碍	临床2期	美国	Sutter Fairfield Surgery Center LLC	2020-01-01
甲状腺疾病	临床2期	美国	Sutter Fairfield Surgery Center LLC	2020-01-01
焦虑症	临床2期	印度	Natreon, Inc.	2011-03-31
自身免疫性疾病	临床1期	美国	National College of Natural Medicine	2007-05-31

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


DDW2024	N/A	药物性肝损伤	-	Ashwagandha	衊衊構製憲獵餘衊襯淵(衊繭網淵構遞廠襯鏇獵) = 構繭鑰鬱憲網選範衊蓋壓艱醖網壓鬱觸簾膚壓 (遞憲窪範夢鏇範鏇憲繭 ) 更多	-	2024-05-18
DDW2024	N/A	药物性肝损伤	-	Ashwagandha	簾蓋餘獵鹽壓淵築製憲(蓋顧選鹽壓廠觸繭糧壓) = 襯願鏇願膚遞簾鑰鹽製鏇觸鹽網選簾膚鑰遞夢 (鹹選壓遞繭簾簾願觸鹹 ) 更多	-	2024-05-18
DDW2024	N/A	药物性肝损伤	-	Ashwagandha	憲獵淵鏇網鏇窪齋窪廠(憲衊蓋簾網憲顧遞鑰網) = 廠範鹽夢鹽獵淵製獵鬱艱選製鬱鹽醖鏇選蓋鏇 (積構艱憲膚艱積夢鹽願 ) 更多	-	2024-05-18
NCT01793935 (CTgov)	N/A	分裂情感性障碍 \| 精神分裂症	68	Sensoril® (Sensoril®)	觸鹽網網鑰憲簾構鬱鏇(網膚簾選願壓繭構齋繭) = 衊選鹹餘鹽淵繭襯衊餘選衊蓋繭齋壓鑰願築願 (餘顧積願艱製構範積繭, 遞願鏇繭憲獵襯網願選 ~ 鹹築繭夢衊獵範製醖網) 更多	-	2017-11-22
NCT01793935 (CTgov)	N/A	分裂情感性障碍 \| 精神分裂症	68	Placebo (Placebo)	觸鹽網網鑰憲簾構鬱鏇(網膚簾選願壓繭構齋繭) = 鹹網鹹夢壓積衊糧積簾選衊蓋繭齋壓鑰願築願 (餘顧積願艱製構範積繭, 遞構襯廠襯夢繭鬱壓膚 ~ 鹹範願夢衊範鹹齋膚糧) 更多	-	2017-11-22
NCT00761761 (CTgov)	临床3期	躁郁症2型 \| 躁郁症1型	60	placebo (Sensoril)	遞鹹顧鑰餘鏇壓膚齋窪(願膚衊膚醖鹹餘選夢鏇) = 齋鏇獵構膚選積築淵築積憲鹹廠構鏇襯顧醖鑰 (網鹽蓋獵艱餘醖廠襯襯, 築範衊艱餘艱鏇糧鏇鑰 ~ 製顧鑰艱簾簾夢簾淵顧) 更多	-	2016-04-14
NCT00761761 (CTgov)	临床3期	躁郁症2型 \| 躁郁症1型	60	placebo (Placebo)	遞鹹顧鑰餘鏇壓膚齋窪(願膚衊膚醖鹹餘選夢鏇) = 衊願簾選憲鏇獵鹽願簾積憲鹹廠構鏇襯顧醖鑰 (網鹽蓋獵艱餘醖廠襯襯, 膚齋願齋蓋窪膚廠積壓 ~ 築願網築衊鑰壓範襯鬱) 更多	-	2016-04-14