Hepatitis B Virus Vaccine(Assiut University)(Hepatitis B Virus Vaccine(Assiut University))

概要

基本信息

药物类型

预防性疫苗

别名-

靶点-

作用机制

免疫刺激剂

治疗领域

感染消化系统疾病皮肤和肌肉骨骼疾病

在研适应症

乙型肝炎疣

非在研适应症-

原研机构

Assiut University

在研机构

Assiut University

非在研机构-

最高研发阶段早期临床1期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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关联

2

项与 Hepatitis B Virus Vaccine(Assiut University) 相关的临床试验

NCT05902624 / Not yet recruiting早期临床1期IIT

Evaluation of the Efficacy of Cryotherapy Combined With Intralesional Hepatitis B Virus Vaccine Versus Either Therapy in the Treatment of Multiple Cutaneous Warts :a Comparative Study

1. investigate the efficacy and safety of combined cryotherapy with intralesional HBV vaccine injection in the treatment of multiple common warts.
2. compare the efficacy and safety of the combined treatment versus either therapy in the treatment of multiple cutaneous warts.

开始日期2024-08-01

申办/合作机构

Assiut University

NCT05967650 / Not yet recruitingN/AIIT

Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract that includes ulcerative colitis (UC) and Crohn's disease (CD) . They mainly affect young populations, altering their quality of life and increasing morbidity, compared to the general population . The etiology and pathogenesis of IBD are still poorly understood.
Inflammatory bowel disease (IBD) patients are at an increased risk of contracting and developing complications from hepatitis B virus (HBV) due to their weakened immune systems and frequent use of immunosuppressive medications. The traditional HBV vaccine regimen requires three doses over six months to achieve full immunity, which can be challenging for IBD patients who may have difficulty adhering to the schedule or may not respond well to the vaccine

开始日期2023-09-01

申办/合作机构

Assiut University

100 项与 Hepatitis B Virus Vaccine(Assiut University) 相关的临床结果

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100 项与 Hepatitis B Virus Vaccine(Assiut University) 相关的转化医学

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100 项与 Hepatitis B Virus Vaccine(Assiut University) 相关的专利（医药）

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626

项与 Hepatitis B Virus Vaccine(Assiut University) 相关的文献（医药）

2024-10-30·Open Forum Infectious Diseases

Hepatitis B Triple Panel Testing Implementation in the Obstetric Care Setting: Unique Predictors of Hepatitis B Virus Vaccine Immunity, Exposure, and Positivity

Article

作者: Rios, Jeanette ; Mageras, Anna ; Lieb, Whitney ; Alpert, Lauren ; Schmidt, Natalia ; Kushner, Tatyana

2024-09-16·Infection control and hospital epidemiology

The association between the timing of initial hepatitis B vaccination and seropositivity in healthcare personnel.

Article

作者: Lees, Elizabeth H ; Breeher, Laura E ; Swift, Melanie D ; Murad, M Hassan

This study reports on the relationship between timing of initial hepatitis B virus (HBV) vaccine series and HBV antibody immunity in healthcare personnel (HCP) screened prior to employment. HCPs vaccinated as neonates were significantly more likely to have negative or indeterminate antibodies. An alternative screening approach is considered.

2024-08-23·Medicine

Female patients with hepatitis B may exhibit a reduced risk of breast cancer: A review of NHANES data

Article

作者: Yang, Siqi ; Zhu, Wenyuan ; Han, Mengyao ; Chen, Yi ; Feng, Jiaxin ; Lin, Sen ; Zhao, Ruiqi

Hepatic viral infections and breast cancer (BC) constitute major global health challenges, yet the interconnection between these hepatic infections and BC continues to be ambiguous. Conducting a comprehensive evaluation of the link between hepatitis virus infection and the incidence of BC and leveraging data from the National Health and Nutrition Examination Survey covering the period from 1999 to March 2022, we utilized logistic regression and subgroup analysis, among other methodologies, to execute a cross-sectional investigation. The univariate logistic regression analysis elucidates that individuals classified as non-Hispanic White exhibit a markedly higher incidence of BC at 2.620 (95% confidence interval [CI], 1.117–7.676; P = .045); moreover, advanced age at 1.063 (95% CI, 1.036–1.093; P < .001), elevated educational attainment at 1.962 (95% CI, 1.17–3.366; P = .012), and higher income levels at 2.835 (95% CI, 1.303–7.439; P = .017) emerge as significant predisposing factors for BC. In contrast, a greater number of live births significantly diminishes the risk of BC, reducing the incidence to 81.1% with each additional birth. Pertaining to hepatitis and vaccination status, our analysis distinctly demonstrates that only hepatitis B at 0.110 (95% CI, 0.018–0.353; P = .002) bears a significant inverse relationship with BC risk, suggesting a protective effect. The multivariate logistic regression analysis further reveals a negative association between hepatitis B infection and BC incidence, whereas hepatitis B vaccination shows a positive correlation with the disease incidence. After adjusting for all covariates, model 3 delineates odds ratios (95% CI) as follows: 0.14 (0.02–0.50; P = .009) and 1.92 (0.99–3.62; P = .046). Our investigation uncovers that within the general populace, there exists an inverse correlation between hepatitis B infection and BC incidence; in addition, the administration of the hepatitis B virus vaccine is potentially positively associated with the prevalence of BC.

100 项与 Hepatitis B Virus Vaccine(Assiut University) 相关的药物交易

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