更新于:2024-11-01

Neuroaxonal Dystrophies

神经轴索营养不良

基本信息

别名
Adult Neuroaxonal Dystrophy、Axonal Dystrophy、Axonal dystrophy
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简介
A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this finding. Neuroaxonal dystrophy is seen in various genetic diseases, vitamin deficiencies, and aging. Infantile neuroaxonal dystrophy is an autosomal recessive disease characterized by arrested psychomotor development at 6 months to 2 years of age, ataxia, brain stem dysfunction, and quadriparesis. Juvenile and adult forms also occur. Pathologic findings include brain atrophy and widespread accumulation of axonal spheroids throughout the neuroaxis, peripheral nerves, and dental pulp. (From Davis & Robertson, Textbook of Neuropathology, 2nd ed, p927)

分析

对领域进行一次全面的分析。
对领域进行一次全面的分析。
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