更新于:2024-05-01

GP2

glycoprotein 2

基本信息

别名
glycoprotein 2、GP2、Pancreatic secretory granule membrane major glycoprotein GP2
+ [2]
简介
Functions as an intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response.

分析

对领域进行一次全面的分析。
对领域进行一次全面的分析。
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