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项与 Sintef AS 相关的药物

TP-1161

靶点-

作用机制-

在研机构-

原研机构

Norwegian University of Science & Technology

在研适应症-

非在研适应症

细菌感染

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ML-449

靶点-

作用机制-

在研机构-

原研机构

Norwegian University of Science & Technology

在研适应症-

非在研适应症

肿瘤

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首次获批国家/地区-

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OXC-201

靶点

OGG1

作用机制

OGG1调节剂

在研机构-

原研机构

Karolinska Institutet [+1]

在研适应症-

非在研适应症

炎症

最高研发阶段无进展

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100 项与 Sintef AS 相关的临床结果

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0 项与 Sintef AS 相关的专利（医药）

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13,621

项与 Sintef AS 相关的文献（医药）

2024-10-02·Sports Biomechanics3区 · 工程技术

Temporal and kinematic patterns distinguishing the G2 from the G4 skating sub-technique

3区 · 工程技术

Article

作者: Austeng, A. ; Meyer, F. ; Danielsen, J. ; Tjønnås, J. ; Sandbakk, Ø. ; Kocbach, J. ; Seeberg, T. M.

In cross-country ski skating, both the G2 and G4 sub-techniques involve one pole push for every second ski push but are used at largely different speed-slope ranges. The aim of this study was to compare temporal and kinematic patterns between G2 and G4 at both identical and different speed-slope conditions. A mixed model was used to analyse spatio-temporal parameters, while a combination of dynamic time warping and statistical parametric mapping was used to compare time traces. Main spatio-temporal parameters, such as cycle time, ski contact time and swing time, differed between G2 and G4 (all p < 0.01). Moreover, two forward and more pronounced acceleration phases of the centre of mass (CoM) were visible in G4 while only one acceleration phase was present in G2. The more continuous propulsion in G2 allows for maintaining a more constant speed at steep slopes and low speeds where this sub-technique is preferred. In contrast, the achievement of high speeds while skiing on flatter terrain seem to require more dynamic motion with shorter, more explosive propulsion periods allowed for in G4. In conclusion, G2 and G4 are two unique movements as characterised by fundamentally different CoM motion and should be denoted as two different sub-techniques.

2024-10-01·Aquaculture International

Evaluation of novel PCR-based method to assess gill injuries in fish caused by the cnidarian Ectopleura larynx

作者: Bloecher, Nina ; Netzer, Roman ; Ribicic, Deni ; Oestevik, Liv ; Floerl, Oliver ; Sivertsgaard, Rolf ; Aas, Marianne ; Kvaestad, Bjarne

AbstractGill disease is a major threat to aquaculture of Atlantic salmon, with an unknown and likely underestimated contribution from cnidarians such as jellyfish and biofouling hydroids. To better understand the risk and thus enable mitigation, technology for the certain identification of cnidarian-related gill damage is needed. We used the hydroid Ectopleura larynx in a case study to determine whether the exposure of salmon to nematocyst-bearing hydrozoans can be deducted via non-destructive PCR-based methods. In a field experiment, we evaluated (i) whether swabbing the inside of the gill operculum in farmed Salmo salar and subsequent PCR analysis can provide quantifiable information about the presence of E. larynx material in the gill chamber and, if so, (ii) whether the screening results correlate with histological assessments of gill damage. The developed PCR methods were able to detect the presence of biofouling hydroids in ambient water. However, despite exposure to suspended hydroid particle concentrations that did result in gill damage in some salmon, quantitative PCR results did not correlate with histological gill assessments. For opercular swabs to serve as a diagnostic tool for detecting biofouling-mediated gill damage in live salmon, increased specificity of genetic markers and improved sampling methods are needed.Animal trial permit no. 24252 (granted 06.07.2020, Norwegian Food Safety Authority).

2024-07-02·Journal of Adhesion Science and Technology

Strengthening the HAZ of an MIG welded joint of 6082-T6 aluminum alloy via mechanical-thermal hybrid aging treatment

作者: Shi, Mingxiao ; Mao, Weidong ; Ma, Xiang ; Yang, Zhidong ; Li, Jingyong

In this work, mech. vibration was applied to the weldment during welding.This technique is called simultaneous mech. aging and combined with post-weld thermal aging to form a mech.-thermal hybrid aging process that was used to strengthen the HAZ of the MIG welded joint of 6082-T6 aluminum alloy.The HAZ softening was significantly reduced through the mech.-thermal hybrid aging treatment, thereby substantially enhancing the joint strength.The β'' precipitated by post-weld thermal aging and the α precipitated by simultaneous mech. aging give rise to precipitation hardening in the HAZ and therefore strengthen the HAZ.Degassing of the weld pool and grain refinement in the weld can be achieved by means of mech. vibration to stir the weld pool.The fracture of welded joints is ductile fracture.

100 项与 Sintef AS 相关的药物交易

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100 项与 Sintef AS 相关的转化医学

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