Evaluation of Curcumin Supplementation on p53 Levels and Apoptosis in Tumor Cells From Patients With Locally Advanced Cervical Cancer
Brief Summary.
The goal of this pilot study is to learn about the effect of curcumin supplementation in locally advanced cervical cancer patients. The main questions it aims to answer are:
Does curcumin supplementation increase the levels of p53 and apoptosis in tumor cells from cervical cancer patients?
At which dose of curcumin supplementation is the broader effect observed for p53 expression and apoptosis in tumor cells from cervical cancer patients?
Are all doses safe for supplementation?
Participants will be asked to take curcumin tablets throughout their cancer treatment. Researchers will compare 6 different groups, each group will receive a different dose of curcumin with or without piperin, to see the dose with the broader effect and safety of curcumin supplementation:
1. 1 g of curcumin
2. 1 g of curcumin + piperine
3. 3 g of curcumin
4. 3 g of curcumin + piperine
5. 6 g of curcumin
6. 6 g of curcumin + piperine
A Double-blind, Placebo-controlled, Parallel Study Evaluating the Safety of Lactospore® in Healthy Individuals
The purpose of this study is to determine whether Lactospore is safe in healthy adults.
A randomized, double blind, parallel group, placebo controlled study to evaluate the safety and efficacy of LactoSpore® (Bacillus coagulans) in patients with diarrhea predominant Irritable Bowel Syndrome.
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