All India Institute of Medical Sciences Raipur (All India Institute of Medical Sciences Raipur)

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74

项与 All India Institute of Medical Sciences Raipur 相关的临床试验

CTRI/2025/04/083966

/ Not yet recruitingN/AIIT

Association between mouthguard wear and traumatic dental injuries in contact sports players aged 10 to 18 in Raipur district - NIL

开始日期2025-06-08

申办/合作机构

All India Institute of Medical Sciences Raipur

CTRI/2025/03/083362

/ Not yet recruitingN/AIIT

Assessment of children and adolescents for Post-Traumatic-Stress-Disorder (PTSD) following maxillofacial and or dental trauma - A Cohort study. - NIL

开始日期2025-04-07

申办/合作机构

All India Institute of Medical Sciences Raipur

CTRI/2025/03/082194

/ Not yet recruitingN/AIIT

An open labelled randomised controlled study to compare the Functional and Radiological outcome of Cemented and uncemented Stem in Total Hip Arthroplasty for Avascular Necrosis of femoral head in patients of Sickle Cell disease - NIL

开始日期2025-04-01

申办/合作机构

All India Institute of Medical Sciences Raipur

100 项与 All India Institute of Medical Sciences Raipur 相关的临床结果

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0 项与 All India Institute of Medical Sciences Raipur 相关的专利（医药）

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733

项与 All India Institute of Medical Sciences Raipur 相关的文献（医药）

2025-05-01·MedComm

The Challenge in Burden of Pulmonary Arterial Hypertension: A Perspective From the Global Burden of Disease Study

Article

作者: Yang, Yicheng ; Thangaraju, Pugazhenthan ; Shu, Songren ; Zou, Zhiyong ; Yan, Wenjie ; Wang, Chuangshi ; Wang, Yaoyao ; Zhang, Hanwen ; Su, Zhanhao ; Safi, Sher Zaman ; Zhou, Jingjing ; Huang, Yuan ; Zeng, Zhiwei ; Xiong, Changming ; Yang, Beilan ; Yang, Qiaoxi ; Wang, Huan ; Wang, Peizhi

ABSTRACTPulmonary arterial hypertension (PAH) poses significant clinical management challenges due to gaps in understanding its global epidemiology. We analyzed PAH‐related disability‐adjusted life years (DALYs), deaths, and prevalence from 1990 to 2021. Age‐period‐cohort models and regression analyses assessed temporal trends and projected burdens to 2050. Globally, PAH‐related DALYs declined by 6.6%, but increased by 13.9% in high socio‐demographic index (SDI) countries. Middle SDI regions reported the highest DALYs in 1990 and 2021. Deaths rose by 48.5% worldwide, with high SDI nations experiencing a 76.6% surge. Age‐standardized rates (ASRs) of DALYs and deaths decreased across SDI countries, with high‐middle SDI regions showing the steepest declines. Younger age groups, especially males, had a higher proportion of global DALYs in earlier years, but the burden shifted toward older populations over time, with this trend more pronounced in high‐SDI countries. Age‐period‐cohort analysis revealed declining DALYs in younger ages but rising rates in older cohorts. By 2050, deaths and prevalence are projected to rise, disproportionately affecting females. Significant regional disparities in PAH burden persist, necessitating targeted policies, improved healthcare access, and early detection strategies, especially in underserved areas. Addressing these disparities is critical for mitigating PAH’ s global impact.

2025-04-01·American Journal of Physiology-Heart and Circulatory Physiology

Leveraging circulating DNase I activity to detect silent coronary artery disease among hypertensive diabetes individuals

Article

作者: Verma, Neha Rani ; Vijay-Kumar, Matam ; Abraham, Jessy ; Babu, Amit ; Uthaiah, Chinnappa A. ; Wasnik, Preetam Narayan

Our observation suggests that the progression of cardiac disease among hypertensive patients with diabetes is associated with elevated DNase I activity that maintains optimal cfDNA levels, thereby reducing its inflammatory potential and worsening of cardiac dysfunction. Thus, DNase I activity may be both a protective factor early on and a potential biomarker for cardiac health among hypertensive patients with diabetes.

2025-04-01·Journal of Human Nutrition and Dietetics

Effect of Predominantly Plant‐Based Diets on Visceral Fat: A Systematic Review and Meta‐Analysis

Review

作者: Gandhi, Aravind P. ; Gumashta, Jyotsna ; Vijayageetha, Mathavaswami ; Vij, Vinu ; Deshmukh, Kalyani ; Goyal, Chanchal

ABSTRACTBackgroundVisceral fat (VF) is a key contributor to metabolic disorders, including type 2 diabetes and cardiovascular diseases. Predominantly plant‐based diets (PPBDs) have been linked to improved body composition and metabolic health. This systematic review and meta‐analysis (SRMA) evaluated the impact of PPBDs on VF.MethodsA systematic search of PubMed, EMBASE, Scopus, Web of Science and Cochrane Library (up to November 2024) identified 13 studies (10 cross‐sectional, 2 randomized controlled trials [RCTs], 1 non‐randomized intervention) with a total of 4000 participants reporting VF outcomes. Risk of bias was assessed using RoB 2.0, ROBINS‐I and JBI tools. Meta‐analyses used random‐effects models, with heterogeneity and publication bias assessed via statistical tests and Doi plots.ResultsRCTs indicated a trend toward VF reduction in those following a PPBD (pooled mean difference: −177.99 cm³; 95% CI: −475.83 to 119.85). Cross‐sectional studies showed significantly lower VF with high adherence to the Mediterranean diet (SMD: −0.45; 95% CI: −0.73 to −0.17; I² = 70%) and modest reductions with vegetarian diets (SMD: −0.24; 95% CI: −0.47 to −0.02; I² = 0%). Sensitivity analyses confirmed the robustness of findings. Certainty of evidence was rated very low.ConclusionPPBDs appear to be associated with lower VF and improved metabolic health, though the certainty of evidence remains very low. Further, well‐powered RCTs are needed to confirm these findings.Trial RegistrationPROSPERO; ID: CRD42024617129. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024617129.

100 项与 All India Institute of Medical Sciences Raipur 相关的药物交易

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100 项与 All India Institute of Medical Sciences Raipur 相关的转化医学

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