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195

项与 The University of Lahore 相关的临床试验

IRCT20200221046567N1 / Suspended临床1期IIT

EFFECTS OF VIRTUAL REALITY WITH MOTOR IMAGERY TECHNIQUES IN ADDITION TO ROUTINE PHYSICAL THERAPY IN PATIENTS WITH PARKINSON’S DISEASE: A RANDOMIZED CONTROLLED TRIAL

开始日期2641-07-06

申办/合作机构

The University of Lahore

IRCT20190912044754N1 / Suspended早期临床1期IIT

COMPARATIVE EFFECTIVENESS OF ROUTINE PHYSICAL THERAPY WITH AND WITHOUT INSTRUMENT ASSISTED SOFT TISSUE MOBILIZATION IN PATIENTS WITH NECK PAIN DUE TO UPPER CROSSED SYNDROME

开始日期2640-12-11

申办/合作机构

The University of Lahore

IRCT20190325043109N1 / Suspended临床1期IIT

Effectiveness of Neuromobilization on Pain,Range of motion,Muscle Endurance and Disability in Cervical Radiculopathy,A Randomized Controlled Trial

开始日期2640-06-22

申办/合作机构

The University of Lahore

100 项与 The University of Lahore 相关的临床结果

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0 项与 The University of Lahore 相关的专利（医药）

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7,000

项与 The University of Lahore 相关的文献（医药）

2025-02-01·Journal of Molecular Structure

In vitro and In silico studies of terpenes extracted from Cymbopogon flexuous leaves against human myeloid leukemia as an inhibitor of NF-κB activation signaling pathway

作者: Mohammed, Osama A. ; Sajid, Arfaa ; Mumtaz, Muhammad Arsalan ; Mehr-un-Nisa ; Imtiaz, Faiza ; Manzoor, Qaisar ; Iqbal, Munawar ; Fatima, Najum ; Sajid, Anam ; Abdel-Reheim, Mustafa Ahmed

Despite recent progress in treating myeloid leukemia (ML) challenges such as the emergence of drug resistance and the persistence of minimal residual disease pose significant obstacles in treating these patients.This highlights the importance of devising novel and innovative strategies to enhance therapeutic outcomes.Citral, myrcene and geranic acid are the major bio-actives of Cymbopogon flexuosus volatile oil (CFVO) that possess strong anticancer potential.This study explored the cytotoxic potential, chem. profiling, and the inhibitory effect of CFVO on nuclear factor-κB (NF-κB) activation pathways.The 3-(4-5-dimethylthiazol-2- yl) 2-5-diphenyl-tetrazolium (MTT) protocol was employed to assess the cell viability.Flow cytometry anal. was performed for assessing the cell cycle and conducting apoptosis assays.Western blot anal. showed that CFVO triggered apoptosis in cancer cells via activating caspases which led to proteolysis of poly ADP ribose polymerase (PARP).Furthermore, electrophoretic mobility shift assay (EMSA) showed that CFVO was capable of suppressing the activation of NF-kB triggered by TNF-α and also resulted in decrease in NF-κB-dependent proteins such as antiapoptotic(cFLIP, Bcl-xL and XIAP) proliferative (Cyclin E1, Cyclin D, C-myc) and invasion (ICAM-1) proteins.Our in sililco study also revealed the binding of anticancer phytochems. with the P50 protein of NF-kB that favors the downregulation of this protein.Inclusively CFVO inhibits the proliferation and metastasis of tumor cells and we can suggest that it will be an effective therapy in fighting against cancer.

2025-01-01·Journal of Molecular Structure

Date seed derived activated carbon functionalized with TiO2 nanocomposite for visible light driven degradation of rhodamine B

作者: Chaudry, Hafiza Alia ; Hussain, Murid ; Tahir, Muhammad ; Akhter, Parveen ; Idrees, Maria

The ongoing approach to overcome the environmental issues have pushed the research to search for sustainable, cost-effective, and valuable materials for dyes degradationIn this study, AC, (activated carbon) TiO₂, (Titanium dioxides) and AC/TiO₂ nanocomposites were fabricated by Sol-gel method and further passed through these characterization techniques such as Fourier Transform IR Spectroscopy (FTIR), X-ray diffraction (XRD), SEM (SEM) and Energy Dispersive X-ray spectroscopy (EDX) and UV-vis spectroscopy to evaluate the phys. and chem. characteristics.Photocatalytic activity was assessed under UV-vis light irradiation, showed pseudo-first-order kinetics of Rhodamine B (Rh B) which showed 85 % removal efficiency from contaminated water under the standard reaction conditions.Various parameters like dose of photocatalyst, (0.1-0.5 g), dye concentrations (10, 20, 30 ppm), pH (acidic, neutral, basic), H₂O₂ conc (1-4 drops).AC/TiO₂ material was found to be highly suitable which showed the better catalytic activity under the optimized reaction conditions (0.1 g dose of catalyst, 20 ppm dye conc, pH acidic media, 150 min light irradiation, 2 drops H₂O₂), enhanced selectivity for degradation of Rh B of 85 %, and greater catalytic stability under 5 cycles of regenerations with well preserved structure of composite.

2024-12-31·Research in Mathematics

Multi-alpha fractal iteration algorithm