The aim of our study is to measure the level of awareness, preconceptions, and level of fear regarding epidural analgesia among childbearing women in KKUH in Riyadh.

开始日期2022-08-01

申办/合作机构

King Khalid University Hospital

[+1]

NCT04716439

/ Unknown statusN/AIIT

Effect of Total Intravenous Anesthesia (TIVA) With Magnesium Sulfate on Intra-Operative Neuromonitoring (IONM) in Patients Undergoing Spine Surgery

Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression. This randomized placebo-controlled, double-blind study was designed to evaluate the effect of magnesium sulfate on the total anesthetic and analgesic consumption using the clinical parameters in addition to the effect on IONM reading.

开始日期2021-02-01

申办/合作机构

King Khalid University Hospital

NCT04680923

/ CompletedN/AIIT

Efficacy of Combined Periportal and Preperitoneal Local Anesthetic Infiltration (CPPLAI) in Laparoscopic Sleeve Gastrectomy Patients

The high demand for bariatric surgery due to the increasing prevalence of obesity worldwide necessitate evidence-based clinical pathway such as Enhanced Recovery After Bariatric Surgery (ERABS). The paradigm of surgery has been shifted from open to laparoscopic in morbidly obese patients. Laparoscopic Sleeve Gastrectomy (LSG) is the most common procedure performed in our institute for sustained weight loss and amelioration of obesity-related comorbidities. Pain control in ERABS is one of the key factors for improved outcomes. Surgery induced acute postoperative pain, stress response and fatigue lead to prolonged convalescence and hospital stay. Optimal titrated safe postoperative pain management in LSG patients still remains a challenge.

开始日期2020-12-08

申办/合作机构

King Khalid University Hospital

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项与 King Khalid University Hospital 相关的文献（医药）

2025-01-01·Journal of Family Medicine and Primary Care

Application of hypertension clinical guidelines among family medicine doctors in primary health care centers in Riyadh City, Saudi Arabia

作者: Alhussain, Abdulaziz ; Alhussain, Abdulelah ; Kofi, Mostafa ; Said, Tarek El ; Aloraini, Abdulmajeed ; Alqahtani, Turki B.

ABSTRACTBackground:Effective management of hypertension relies on adherence to evidence-based clinical practice guidelines (CPGs) among healthcare providers. However, adherence to hypertension CPGs and the factors influencing it among primary care physicians in Riyadh, Saudi Arabia, remain poorly understood.Methodology:This descriptive cross-sectional study aimed to assess the knowledge, application, and determinants of adherence to hypertension CPGs among primary care physicians working in Prince Sultan Military Medical City (PSMMC) and its affiliated primary health care centers in Riyadh, Saudi Arabia. A comprehensive sample of 211 primary care physicians was enrolled, and data were collected using a self-administered questionnaire covering demographic characteristics, adherence to hypertension CPGs, and barriers to guideline application. Descriptive statistics and appropriate statistical tests were used for data analysis.Results:The demographic profile of participants revealed a comprehensive representation of age, marital status, nationality, job title, qualification, and years of practice. The majority of participants demonstrated acceptable levels of knowledge (76.3%) and application (89.1%) of hypertension CPGs. However, barriers related to patient nonadherence to lifestyle modifications and medications were reported, highlighting challenges in implementing guideline recommendations in clinical practice. Significant associations were found between nationality, job title, qualification, and adherence to CPGs, with non-Saudi nationality and junior physicians exhibiting higher rates of unacceptable knowledge and application. Moreover, differences in adherence were observed among physicians following different hypertension CPGs.Conclusion:While primary care physicians in Riyadh demonstrate a strong foundation in evidence-based hypertension management, addressing barriers and disparities in adherence to CPGs requires targeted interventions and collaborative efforts. Promoting a culture of evidence-based practice, enhancing patient education and engagement strategies, and fostering collaboration among stakeholders are essential steps toward improving hypertension control and prevention in the region.

2025-01-01·Clinical Lymphoma Myeloma and Leukemia

Discontinuation of Tyrosine Kinase Inhibitor Therapy and Treatment Free Remission (TFR) in Chronic Myeloid Leukemia: Successful Achievement of TFR in More Than Two-Third of Patients in a Real-World Practice

Article

作者: Shaheen, Naila A ; Aleem, Aamer ; Iqbal, Zafar ; Marei, Mohammed A ; Siti, Hajar Wan Zuki ; Alzahrani, Mohsen ; Algahtani, Farjah ; Alghafis, Mashail ; Alrajhi, Abdullah ; Shaheen, Naila A. ; Alaskar, Ahmed ; Alkhudair, Nora ; Thomas, Abin ; Gmati, Giamal ; Jamal, Ahmed ; Alhejazi, Ayman ; Alahmari, Bader ; Marei, Mohammed A. ; Alfayez, Mansour ; Salama, Hind

BACKGROUNDDiscontinuation of TKI therapy and treatment-free remission (TFR) have become new goals for chronic-phase chronic myeloid leukemia (CP-CML). The aim of this study was to estimate the TFR post discontinuation of TKI therapy at 3 tertiary-care centers.PATIENTS AND METHODSCP-CML patients aged ≥16 years who had an attempt to discontinue TKI therapy till June 2022, were eligible. The collected data included patients' demographics, prognostic score, type and duration of TKI therapy, response dates, relapse dates, response to re-initiation of TKI therapy, and risk factors for relapse.RESULTSFifty-five patients (35, 63.6% females) with a median age of 40 (range 16-74) years at diagnosis discontinued therapy. Forty-eight (87.3%) patients received imatinib as first line therapy. Twenty-nine (52.7%) patients were receiving imatinib at the time of TKI-discontinuation. Median time from diagnosis to TKI discontinuation was 86 months (IQR 60;132) and median duration of TKI therapy after achieving DMR was 66 months (IQR 47;114). After a median follow up of 34 (IQR 12;68) months, 15 (27.3%) patients relapsed. Median time to relapse was 5 months (range 2-38). Most of the relapses occurred during the first 6 months except 3 (20%) patients. All the relapsed patients achieved MMR after a median of 3 (range 2-6) months after restarting TKI therapy. None of the patients progressed to advanced-phase.CONCLUSIONOur experience confirms that discontinuation of TKI therapy in CP-CML patients is feasible and safe in routine clinical practice, and can achieve TFR in more than two-third of carefully selected patients.

2024-12-28·Cureus

Knowledge, Attitude, and Perception Toward Evaluation of Acute Heart Failure Among Emergency Medicine Residents in Riyadh, Saudi Arabia

Article

作者: Alkhanbashi, Haneen ; Alkhars, Ahmed M ; Nassar, Saeed ; Almezeiny, Tawfiq

BACKGROUNDAcute heart failure (AHF) poses significant challenges in clinical practice due to its varied clinical presentations and complex management strategies. Adequate confidence levels among medical residents in diagnosing and managing AHF are crucial for timely and effective patient care.STUDY AIMThis cross-sectional study aimed to assess medical residents' knowledge, attitude, and perception levels in diagnosing and managing AHF and explore factors influencing their confidence levels.METHODOLOGYA total of 52 medical residents from various specialties participated in the study. Based on different clinical parameters, participants completed a questionnaire assessing their confidence levels in diagnosing AHF. Descriptive statistics were used to summarize confidence levels, while chi-square tests explored associations between demographic/clinical factors and confidence levels.RESULTSThe majority of residents exhibited high confidence levels in diagnosing heart failure (HF) based on history and physical examination findings alone (22 (42.3%) and 16 (30.8%), respectively). However, confidence levels were lower when relying solely on laboratory tests and imaging modalities for diagnosis (17 (32.7%) and 18 (34.6%), respectively). Factors such as symptoms (e.g., dizziness) and availability of ultrasound equipment were associated with higher confidence levels (p < 0.05). However, demographic factors such as age, gender, and residency year did not significantly influence confidence levels (p > 0.05).CONCLUSIONOur study highlights variations in confidence levels among medical residents in diagnosing and managing AHF. While clinical assessment remains paramount, targeted educational interventions focusing on interpreting diagnostic tests and imaging findings are warranted to enhance residents' confidence levels and improve patient care.

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