Riphah International University

Soft tissue sarcomas (STS) are rare and aggressive tumors with limited treatment options. A recent study by Burkhard-Meier et al. highlights Local Ablative Therapy (LAT) as a promising approach for metastatic STS, particularly pulmonary metastasectomy, which showed the best survival outcomes. Smaller tumors and longer treatment-free intervals were key predictors of success. Combining LAT with systemic therapy further improved progression-free survival. Advancements in stereotactic body radiation therapy (SBRT) offer potential benefits for STS, though data remains limited. While SBRT has shown success in breast and lung cancers, its role in STS requires further research. Until more trials confirm its efficacy, traditional LAT remains the preferred approach for carefully selected patients.

In this research, we calculated the optoelectronic and transport properties of three-dimensional (3D) bulk and two-dimensional (2D) surface (110) structures using the Modified Becke-Johnson plus Hubbard U (mBJ + U) method within the framework of D. Functional Theory (DFT).All calculations were performed using the WIEN2k code.The study includes the calculation of electronic properties, such as band structures and d. of states, for both bulk and surface (110) configurations.For the MnMoO₄ (110) surface, the spin-up state has an indirect band gap of 1.69 eV with VBM at Γ and CBM between Γ and M points.The spin-down state shows an indirect band gap of 2.613 eV with VBM at Γ and CBM at M.In bulk MnMoO₄, the spin-up state exhibits a direct band gap of 2.18 eV between R and Γ points, while the spin-down state has an indirect band gap of 3.746 eV with VBM at X and CBM between Γ and R.Significant transitions, primarily attributed to interactions among O-s/p, Mn-p, and Mo-d orbitals, were calculated in both structures.The energy loss function, dominated by plasmon energy peaks, showed a value of 13.6 eV for both bulk and surface (110) structures.The real and imaginary components of the dielec. function were also computed, revealing strong peaks in the visible region, further validating the material′s potential for optoelectronic applications.The surface (110) material demonstrated superior optoelectronic efficiency due to its direct and lower band gap, making it an excellent candidate for optical device applications.Both bulk and surface materials exhibited strong optical absorption in the visible to UV spectrum.The reflectivity spectra indicated low reflectivity values in the visible spectrum, which, combined with high absorption, suggests strong suitability for photovoltaic and photo-detection applications.The reflectivity spectra suggest their potential as coating materials for reducing solar heating, which is advantageous in solar cell technologies.Addnl., the transport properties, including Seebeck coefficient and thermal conductivity, suggest promising applications in thermoelec. devices.The low thermal conductivity and high power factor for the surface configuration also contribute to an enhanced thermoelec. figure of merit (ZT), making it particularly promising for waste heat recovery technologies.This study highlights the potential of the surface (110) structure in enhancing the performance of optoelectronic devices, while also supporting the application of both bulk and surface materials in solar cells and thermoelec. technologies.

The structural, electronic, optical, elastic, mech. and thermoelec. properties of cubic LaAlO₃ are studied under different pressure ranges (0-100 GPa) using first-principles calculationsThe calculations are done using the Generalized Gradient approximation-Perdew-Burke-Ernzerhof (GGA-PBE) by utilizing the CASTEP code.The presence of pos. phonon affirms the dynamical stability of cubic LaAlO₃ compound under applied pressures.It was noticed that with the increase of applied pressure, the band gap increased and the nature of the band gap changed from being indirect to direct at 60 GPa.The optical aspects of cubic LaAlO₃ have been thoroughly studied via the use of different optical parameters like the complex refractive index, complex dielec. function, absorption coefficient, energy loss function, real optical conductivity and reflectivity.These investigations cover a broad energy range from 0-50 eV.The photon absorption initiates in the visible region, with the highest level of absorption occurring inside the UV energy range.Our study indicates that LaAlO₃ sustains its cubic phase and has superb mech. stability, demonstrating its brittle nature under applied pressure between 0 and 100 GPa.The pos. values of the Hall coefficient confirm that the holes are the predominant carriers under all externally given pressures from 0 to 100 GPa.As a result, the cubic LaAlO₃ perovskite oxide exhibits suitability for energy-efficient white-LED devices and different optoelectronic applications across various applied pressures.