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Provided herein are novel bicyclic amines as CDK2 inhibitors, pharmaceutical compositions, use of such compounds in treating metastatic breast cancer or metastatic lung cancer and processes for preparing such compounds.

2025-02-13·ACS Medicinal Chemistry Letters

Novel Imidazo[4,5-c]pyridine Compounds as TLR7 Agonists for Treating Cancer

作者: Sabnis, Ram W.

Provided herein are novel imidazo[4,5-c]pyridine compounds as TLR7 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.

2024-06-13·ACS Medicinal Chemistry Letters

Imidazopyridine Compounds as ERK5 Inhibitors for Treating Cancer

作者: Sabnis, Ram W.

A review.Provided herein are novel imidazopyridine compounds as ERK5 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds

100 项与 Smith, Gambrell & Russell LLP 相关的药物交易

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100 项与 Smith, Gambrell & Russell LLP 相关的转化医学

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药物(靶点)	适应症	全球最高研发状态

SLC6A19 inhibitors(Smith, Gambrell & Russell) ( SLC6A19 )	苯丙酮尿症更多	药物发现
MRGPRX2 antagonists(Smith, Gambrell & Russell) ( MRGPRX2 )	炎症更多	药物发现
NLRP3 inhibitors(Smith, Gambrell & Russell) ( NLRP3 )	哮喘更多	药物发现
EBP inhibitors(Smith, Gambrell & Russell) ( EBP )	多发性硬化症更多	药物发现
QPCTL inhibitors(Smith, Gambrell & Russell) ( QPCTL )	肿瘤更多	药物发现