A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital In- Office Bleaching Agent :A Controlled Clinical Trial

The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
The discoloration of teeth might be intrinsic, extrinsic, or combined. A variety of commercial bleaching agents is available. The most common substances used are carbamide peroxide or hydrogen peroxide or a mixture of sodium perborate and hydrogen peroxide.

开始日期2025-01-15

申办/合作机构

Misr University For Science And Technology

NCT06578403

/ Not yet recruitingN/AIIT

Minimally Invasive Non-surgical Therapy Augmented With Internal Versus External Micro-needling in Treatment of Stage Iii Periodontitis: a Randomized Controlled Clinical Trial and Biochemical Trial

Periodontitis is a dysbiotic disease characterized by the destruction of the periodontium (alveolar bone, cementum, periodontal ligament, gingiva) and considered the main cause of tooth loss which is linked to a change in the microbial community from primarily beneficial bacteria, known as 'symbionts', to an imbalance with a high presence of harmful bacteria 'dysbiosis', also known as 'pathobionts'.
Ideally, periodontal therapy should eliminate inflammation, arrest the advancement of periodontal disease, enhance appearance, and create an environment conducive to health maintenance.Microneedling (MN) is known as "percutaneous collagen induction therapy." Micro injuries created by MN result in minimal superficial bleedings and create a wound-healing The body responds to micro-needling as if it's experiencing tissue trauma, leading to the release of various growth factors such as platelet-derived growth factors, transforming growth factors, connective tissue growth factors, and fibroblast growth factors. These growth factors induce the production of collagen to preserve skin integrity. After an injury, growth factors are released, promoting the proliferation of new cells. From day 5 to week 8, fibroblasts produce collagen and elastin fibers, thickening the tissue in a process known as neocollagenesis. Additionally, fibroblasts trigger neoangiogenesis by stimulating the proliferation of endothelial cells in the vessels. According to a randomized clinical trial comparing micro-needling and acellular dermal matrix, significant improvements were observed in various parameters(GT, RW, RD, CAL, PD, Rec- Red, and percentage of root coverage, with reduced PI and BOP at 3 and 6 months this study aim to The effect of minimally invasive non-surgical augmented with micro-needling, both externally and internally, for the management of stage III periodontitis

开始日期2024-12-01

申办/合作机构

Misr University For Science And Technology

NCT06676475

/ Not yet recruiting临床2/3期IIT

Comparison of the Effectiveness of Botulinum Toxin and Magnesium Sulfate Injections in the Treatment of Myofascial Trigger Points in the Masseter Muscle Randomized Controlled Clinical Trial

The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years old with myofascial pain with masseter muscle trigger points. The main questions it aims to answer are:
* which treatment has longer effect of pain release with the least possible side effects and recurrence rate?
* Which treatment has greater impact on improving patient's quality of life? Researchers will compare Botulinum toxin type A, magnesium sulfate to a placebo saline injections in treatment of the masseter muscle trigger points Participants will attend to the clinic 4 times
* 1st visit will include taking preoperative records and treatment injection
* 2nd visit will be follow up and taking records after 1 month
* 3rd visit will be follow up and taking records after 3 months
* 4th visit will be follow up and taking records after 6 months

开始日期2024-12-01

申办/合作机构

Misr University For Science And Technology

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项与 Misr University For Science And Technology 相关的文献（医药）

2025-12-31·GM Crops & Food

Development of transgenic wheat plants withstand salt stress via the MDAR1 gene

Article

作者: Hassanein, Sameh E. ; Ramadan, Ahmed M. ; Saleh, Osama M. ; Fahmy, Eman M. ; Eltayeb, Amin E. ; Hassan, Sabah M. ; Abdel-Tawab, Fatthy M. ; Al-Saud, Najla B. S. ; Bahieldin, Ahmed ; Alameldin, Hussien. F. ; Eissa, Hala F. ; Abdel Azeiz, Ahmed Z. ; Abdelsattar, Mohamed ; Ali, Hani M. ; Mohamed, Nermin G.

In light of the fact that climate change has emerged as one of the difficulties confronting the global food system, researchers are obligated to work toward developing fundamental crops, particularly wheat, to combat environmental stress, including drought and salt. In the present study, genetic engineering was used to transfer the Arabidopsis MDAR1 gene, which controls the buildup of ascorbic acid (AsA) to make bread wheat less likely to be sensitive to salt stress. The biolistic bombardment was used to transfer cDNA from the Arabidopsis thaliana plant that encodes MDAR1 into Bobwhite 56 cultivar wheat plants. A molecular investigation was performed on six different transgenic lines to confirm the integration of the transgene, the copy number, and the expression of the transgene. There were one to three copies of the transgene, and there was no association found between the number of copies of the transgene and All the data generated or analyzed during this study are included in this published article [and its supplementary information files].the presence of its expression. Compared to plants that were not transgenic, the amount of ascorbic acid (AsA) that accumulated in the transgenic plants was twice as high. ROS concentrations are significantly lower in transgenic plants compared to non-transgenic plants under both control and salt stress conditions, effectively reducing oxidative stress. By cultivating transgenic T2 plants in a greenhouse, we were able to determine whether they were able to tolerate the potentially damaging effects of salt stress (200 mm). The study concluded that transgenic wheat plants that consistently expressed the MDAR1 gene become tolerant to salt stress with improvement in growth characteristics.

2025-07-01·Materials Science and Engineering: B

Evaluating the performance of metal-doped anthracene nanotubes for gas sensing applications

作者: Saroka, Vasil A. ; Abdelrazek, Ghada M. ; Abd-Elkader, Omar H. ; Zhang, Qinfang ; Abdelsalam, Hazem ; Sakr, Mahmoud A. S.

This study investigates the structural, electronic, optical, and gas adsorption properties of transition metal (Cu, Ni, Fe) and alkali metal (Li, Mg) doped anthracene nanotubes (An-NT).Structural optimizations reveal significant changes in bond lengths and angles due to metal doping, with Fe-doped A6-NT showing the most stability (binding energy: 7.63 eV).Electronic anal. indicates that Cu and Li doping reduce the energy gap (Eg), enhancing conductivity in A6-NT (Eg = 0.513 eV) and A7-NT (Eg = 0.601 eV).Conversely, Fe, Ni, and Mg doping lead to wider energy gaps, indicating reduced conductivityOptical properties reveal significant variations in the absorption spectra, correlating with the d. of states (DOS) that shift upon doping, suggesting potential tunability for optoelectronic applications.Gas adsorption studies show enhanced interaction for CH₄ and CO₂, with Fe-doped A6-NT and A7-NT exhibiting the highest adsorption energies.This positions them as promising candidates for gas sensing and storage applications, showcasing the potential of metal-doped anthracene nanotubes in electronic devices and gas capture technologies.

2025-07-01·Inorganic Chemistry Communications

Comparative study of hydrogen adsorption and storage in Arsenene, Antimonene, Phosphorene, and Bismuthene quantum dots

作者: Abdelrazek, Ghada M. ; Abd-Elkader, Omar H. ; Zhang, Qinfang ; Abdelsalam, Hazem ; Teleb, Nahed H. ; Sakr, Mahmoud A. S.

This study explores the structural, stability, electronic, adsorption, and hydrogen storage properties of quantum dots (QDs) derived from Arsenene (As₄₂), Antimonene (Sb₄₂), Phosphorene (P₄₂), and Bismuthene (Bi₄₂).The binding energies (BE) for these QDs were calculated as 3.622 eV, 3.222 eV, 3.756 eV, and 3.302 eV, resp., with P₄₂ demonstrating the highest stability.P₄₂′s strong covalent bonding and As₄₂′s balanced structural features suggest potential for enhanced stability.Hydrogen adsorption properties were analyzed, revealing Sb₄₂ QDs as highly promising for moderate hydrogen loads with adsorption energies (E_a) within the Department of Energy′s optimal range (-0.2 to -0.7 eV), such as -0.594 eV for Sb₄₂-10H₂.Furthermore, the hydrogen storage capacities of Sb₄₂ QDs exceeded other materials, achieving desorption temperatures (T_D) of 200 K for moderate loads, facilitating practical hydrogen release.Optical studies demonstrated a red shift in Sb₄₂′s absorption spectrum (λ_max = 960 nm) compared to other QDs.These findings highlight the potential of Sb₄₂ for hydrogen storage and P₄₂ for stable applications, offering insights into the performance and application of QDs in advanced energy systems.

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