Analysis of physiological markers of bone remodeling, muscle strength, functional autonomy, self-esteem and self-image in elderly undergoing adapted Taekwondo

开始日期2022-02-06

申办/合作机构

Universidade Estácio de Sá

[+1]

RBR-3xr6dv

/ RecruitingN/AIIT

Comparison between 0,4% Oxibuprocaine corneal anesthesia applied by Eyedrops or Spray

开始日期2019-06-27

申办/合作机构

Universidade Estácio de Sá

[+1]

RBR-4gjhfk

/ Not yet recruiting临床4期IIT

Anesthetic effect of Proximetacaine hydrochloride 0,5%: comparison between eyedrop instillation in open eyes and vaporization in closed eyes

开始日期2018-10-01

申办/合作机构

Universidade Estácio de Sá

[+1]

100 项与 Universidade Estácio de Sá 相关的临床结果

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0 项与 Universidade Estácio de Sá 相关的专利（医药）

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714

项与 Universidade Estácio de Sá 相关的文献（医药）

2025-06-01·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Exploring mandibular buccal bifurcation cysts: a case series and a comprehensive literature review

Article

作者: de Souza, Lucas Lacerda ; Delli, Konstantina ; Santos-Silva, Alan Roger ; Lopes, Márcio Ajudarte ; Nikitakis, Nikolaos G ; Miranda, Águida Maria Menezes Aguiar ; Vargas, Pablo Agustin ; Pires, Fabio Ramoa ; Pontes, Helder Antônio Rebelo ; Correia-Neto, Ivan José ; Pontes, Flávia Sirotheau Correa

OBJECTIVEThe objective of this study was to explore the clinical and microscopic findings of mandibular buccal bifurcation cysts (MBBCs) in an original case series and to perform a literature review of this lesion.STUDY DESIGNParaffin-embedded tissue blocks from patients microscopically diagnosed with MBBCs were retrieved from 4 oral and maxillofacial pathology archives. Data, including clinical, radiographic, and microscopic characteristics, treatments used, and follow-up status, were collected from the pathology records.RESULTSA total of 23 cases were examined, consisting of 10 male subjects (43.47%) and 13 female subjects (56.52%). The mean age of the subjects was 10.52 years, with a range from 6 to 42 years. The majority involved the first molar, accounting for 19 cases (82.60%), whereas the second molar was affected in 4 cases (17.39%). Only 2 cases presented with bilateral lesions (8.69%), with the remaining 21 cases showing unilateral occurrence (91.30%). Treatment predominantly involved enucleation, utilized in 16 cases (69.56%). The average follow-up period was 6.5 months, ranging from 1 to 27 months.CONCLUSIONSThis study highlights the diagnostic challenges and treatment considerations associated with MBBC, emphasizing the importance of a conservative approach, particularly in young patients, to preserve dental function and normal facial growth.

2025-04-01·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Intraosseous benign peripheral nerve sheath tumor of the jaws: report of 4 new cases and a comprehensive literature review

Review

作者: VARGAS, Pablo Agustin ; Rocha, André Caroli ; LOUREDO, Brendo Vinícius Rodrigues ; TORRES, Alexandre Machado ; PENAFORT, Paulo Victor Mendes ; Oliveira, Maria Cecília Querido De ; PIRES, Fábio Ramoa ; Roza, Ana Luiza Oliveira Corrêa ; ROCHA, André Caroli ; Jorge-Júnior, Jacks ; Pires, Fábio Ramoa ; Ocaña, Ricardo Pelletti ; FERREIRA JÚNIOR, Samuel de Barros ; JORGE-JÚNIOR, Jacks ; OCAÑA, Ricardo Pelletti ; ROZA, Ana Luiza Oliveira Corrêa ; Louredo, Brendo Vinícius Rodrigues ; COSTA, Rafael Cabral da ; Ferreira Júnior, Samuel de Barros ; Penafort, Paulo Victor Mendes ; OLIVEIRA, Maria Cecília Querido DE ; PRADO, José Divaldo ; Prado, José Divaldo ; Costa, Rafael Cabral da ; Vargas, Pablo Agustin ; Torres, Alexandre Machado

Benign peripheral nerve sheath tumors (BPNSTs) are a vast, common, heterogeneous group of lesions that are often diagnostically challenging. The head and neck region is recognized as the second most common location for these lesions, especially the tongue. However, BPNSTs occurring centrally within the jaw bones are exceedingly rare. To date, approximately 161 cases of intraosseous BPNSTs have been reported in the jaws. This group mainly includes the relatively more common neurofibromas and schwannomas, and the less common perineuriomas and hybrid forms. Unlike soft tissues, schwannomas are the most common BPNSTs occurring within the jaws, followed by neurofibromas and perineuriomas. These neoplasms can present as a well-defined unilocular lesion or as an ill-defined multilocular image, resembling several types of benign and malignant lesions of odontogenic origin. The aim of the current study was to report 4 new cases of intraosseous BPNSTs and a comprehensive literature review.

2025-04-01·CHEST

Ventilatory Efficiency in Transgender Women: Implications of Gender-Affirming Hormone Therapy on Cardiorespiratory Responses

Article

作者: Kalichsztein, Bruna ; Domecg, Fernanda ; Mourilhe-Rocha, Ricardo ; Fiorelli, Rossano ; Milani, Mauricio ; Junior, Gerson Cipriano ; Hansen, Dominique ; Fachetti, Ana Carolina ; Braga, Fabrício ; Zagury, Roberto ; De Marca, Karen ; Espinosa, Gabriel

BACKGROUNDVentilatory efficiency, a key parameter of cardiopulmonary function assessed through cardiopulmonary exercise testing (CPET), often demonstrates significant variability in transgender women due to the physiological changes induced by gender-affirming hormone therapy. Understanding these differences is essential for optimizing clinical management and enhancing health outcomes within this population.RESEARCH QUESTIONHow do ventilatory efficiency, particularly the carbon dioxide ventilatory equivalent (VE/VCO₂), and other CPET variables differ between transgender women and matched cisgender controls, offering insights into the physiological impacts of gender-affirming hormone therapy?STUDY DESIGN AND METHODSThis case-control study included 51 participants, comprising 17 transgender women matched 1:1:1 by age, body mass index, and physical activity levels with cisgender women and cisgender men. CPET assessments were conducted between August 2018 and September 2019, before the COVID-19 pandemic.RESULTSTransgender women demonstrated significantly higher VE/VCO₂ ratios at rest (31.4 ± 2.9), at the first ventilatory threshold (34.9 ± 3.9), and peak exercise (39.3 ± 5.3) compared to cisgender women (28.2 ± 2.5; 31.8 ± 3.2; 35.4 ± 4.4, respectively) and cisgender men (27.4 ± 2.1; 30.8 ± 2.6; 34.3 ± 3.5, respectively), with all comparisons reaching statistical significance (p < 0.001) and large effect sizes (η² = 0.30-0.34). The VE/VCO₂ slope was also significantly elevated in transgender women (33.9 ± 4.2) compared to cisgender women (29.5 ± 5.0) and cisgender men (28.0 ± 3.5) (p < 0.001; η² = 0.29), indicating reduced ventilatory efficiency across the effort continuum.INTERPRETATIONThis study highlights substantial ventilatory inefficiencies in transgender women, likely associated with gender-affirming hormone therapy, underscoring the need for tailored clinical strategies to address these cardiopulmonary adaptations. These findings provide critical insights into the unique health needs of transgender individuals, contributing valuable data to support evidence-based care.

100 项与 Universidade Estácio de Sá 相关的药物交易

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100 项与 Universidade Estácio de Sá 相关的转化医学

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