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最高研发阶段终止 |
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/ Not yet recruitingN/AIIT Reuse of Polyp Traps, a Way to Approach Sustainability: A Multicentric Non-inferiority Study
The environmental impact of healthcare practice in the context of climate change is in the spotlight. Digestive endoscopy units are the third hospital unit that generates the most waste and environmental impact. For this reason, scientific societies advice studying and adopting more sustainable clinical practices, reconsidering current protocols for reprocessing and disinfection of single-use material. One of the devices, widely used and which generates a large amount of waste, is the polyp trap. It allows an easy recovery of the polyps removed during endoscopy. This device is discarded after a single use in some centers, and reused after washing and disinfection in others. Manufacturers recommend the single-use of the device, even there is no scientific evidence to support this action. In the investigators endoscopy unit, 3800 polyp traps are used yearly. The investigators hypothesis is that reusing the polyp catcher has similar safety to disposal after a single use, with better environmental and economic results. Objectives: To evaluate the safety of the reused and discarded after a single-use polyp trap. The investigators will assess 1) the post-colonoscopy infection rate and 2) the reliability of the anatomopathological study, 3) CO2 emissions and 4) costs of each practice. Methodology: A non-inferiority study will be carried out by observing the usual clinical practice of different centers and collecting data that suggest infection, cross-sampling and general complications. The results will be easily applicable in endoscopy units and will serve as a basis for future studies with other more controversial devices.
/ Not yet recruitingN/AIIT Validation of a Questionnaire to Measure Cough Severity in Patients with Chronic Cough
To design and validate a questionnaire that allows objective assessment of the severity of chronic cough
Phase Ib/II Study to Investigate the Safety and Efficacy of Afatinib When Administered As Therapy in Fanconi Anemia Patients with Unresectable and / or Metastatic Locoregionally Advanced Squamous Cell Carcinoma of the Oral Cavity, Oropharynx or Hypopharynx or Larynx.
This research study is a phase Ib/II, single-arm, non-randomized, non-blind, multicenter study designed to determine whether Afatinib is effective and safe in patients with locoregionally unresectable and / or metastatic HNSCC with Fanconi Anemia.
The main hypothesis, based on preclinical evidence, is that treatment with afatinib, an epithelial growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), could be an effective treatment option to control cancer for patients with FA - HNSCC.
100 项与 Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau 相关的临床结果
0 项与 Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau 相关的专利(医药)
100 项与 Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau 相关的药物交易
100 项与 Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau 相关的转化医学