Synthesis of 2-acetonyloxo-3,4-difluoronitrobenzene
作者: Liang, Yanyu ; Wang, Bin ; Wang, Jiesheng
An improved procedure for preparation of the title compound (I) is presented.Condensation of 2,3,4-trifluoro-nitrobenzene with 2-hydroxymethyl-2-methyl-1,3-dioxane followed by hydrolysis to give I with a yield of 90%.
Jingxi Huagong
Synthesis of L-(+)-alaninol
作者: Qiu, Jun ; Zhang, Yu-hong ; Ling, Jun ; Wang, Bin ; Wu, Yi-ming
The synthesis of L-(+)-alaninol was described.L-Alanine, as starting material, was esterified with thionyl chloride and ethanol.The ester formed was reduced by zinc borohydride and hydrolyzed with sodium hydroxide to yield the title compound with 60% overall yield and 99% content.Zinc borohydride was prepared by the reaction of potassium borohydride and anhydrous zinc chloride.
Huaxue Shiji
Synthesis of 9-(2-hydroxyethyl) adenine
作者: Meng, Jin-ning ; Zhao, Yang
9-(2-Hydroxyethyl) adenine was prepared from ethylene carbonate and adenine with recycling of DMF solvent.