A review. Most diets in developed nations fall far short of recommended fruit and vegetable, and thus key nutrient, intake. Momordica cochinchinensis (gac), indigenous to Southeast Asia, contains high concentrations of lycopene and beta-carotene. In Vietnam, gac is prized by natives for promoting longevity and vitality. In a supplementation trial among Vietnamese children, gac increased serum vitamin A levels more than synthetic beta-carotene. Rosa roxburghii (cili), native to southwest China and traditionally used to combat stress and aging, is very rich in vitamin C and other phytonutrients. In humans, cili enhanced immunity and raised erythrocyte superoxide dismutase (SOD). Lycium chinense (wolfberry), also of Chinese origin, and traditionally used for longevity, wellness, and vision, is very rich in highly utilizable zeaxanthin. In animals, wolfberry showed immune modulating and antioxidant actions, and in humans, significantly increased blood SOD. Hippophae rhamnoides (sea buckthorn), native to Siberia and the Himalayas and traditionally used to expel phlegm and promote digestion, was shown in animals to have liver-protective and antioxidant activity. In humans, sea buckthorn greatly increased the dietary intake of flavonoids and vitamin C, and showed cardiovascular benefits. Thus, due to their nutritional value, intake of these fruits may greatly enhance the diet's healthfulness.