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79

项与 Kagome Co., Ltd. 相关的临床试验

JPRN-UMIN000054045

/ SuspendedN/A

Verification of the effect of different intake times on the absorption of food components: open-label, crossover trial - Verification of the effect of different intake times on the absorption of food components

开始日期2024-04-08

申办/合作机构

Kagome Co., Ltd.

[+1]

NCT06271070

/ CompletedN/A

Analysis of Correlation Between Skin Carotenoid Level and Basic Indicators of Health Status Related to Lifestyle in Vietnamese: An Observational Study

To clarify the relationship between vegetable intake and lifestyle-related disease in Vietnam, we measure skin carotenoid levels and basic indicators of health status related to lifestyle and analyze the correlation between them. This is an important study that can lead to dietary suggestions for preventing lifestyle-related diseases in Vietnam.

开始日期2024-01-30

申办/合作机构

Kagome Co., Ltd.

JPRN-UMIN000053092

/ CompletedN/A

Development of a vegetable intake method useful for blood glucose control -Verification of the vegetable juices consumption immediately before a meal on postprandial blood glucose levels- - Development of a vegetable intake method useful for blood glucose control -Verification of the vegetable juices consumption immediately before a meal on postprandial blood glucose levels-

开始日期2023-12-18

申办/合作机构

Kagome Co., Ltd.

100 项与 Kagome Co., Ltd. 相关的临床结果

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0 项与 Kagome Co., Ltd. 相关的专利（医药）

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320

项与 Kagome Co., Ltd. 相关的文献（医药）

2025-06-01·Biological Control

Suppressive effects of Levilactobacillus brevis on Fusarium-plant disease and its potential contribution to environmentally friendly agriculture

作者: Nakashima, Yoshiko ; Yamauchi, Norihito ; Murano, Hirotatsu

To harmonize with sustainable practices, chem. pesticide use is being reduced globally, and more farmers are adopting environmentally friendly agricultural methods.In this context, lactic acid bacteria (LAB) have garnered increasing attention as potential biocontrol agents, biostimulants, and biofertilizers; however, the mechanisms underlying their effects remain unclear.Levilactobacillus brevis KB290, a heterofermentative bacterium that produces acetic and lactic acids, and Lacticaseibacillus paracasei KB182-SBR1202, a homofermentative bacterium that produces only lactic acid via which it suppresses Fusarium growth, both in vitro and in natural soil, are being explored for their inhibitory mechanisms.At concentrations of 10¹ and 10⁶ CFU mL^-1, L. brevis reduced Fusarium growth by 36 % and 100 %, resp., whereas at concentrations of 10⁶ CFU mL^-1L. paracasei only reduced Fusarium growth by 14 %.To understand the inhibitory mechanism, LAB were cultured in liquid media and organic acid concentrations were measured.L. paracasei produced only lactic acid, whereas L. brevis produced lactic and acetic acids.The IC₅₀s for lactic and acetic acids were 18.4 mM and 9.72 mM, resp.Acetic acid completely inhibited Fusarium growth, whereas lactic acid did not achieve complete inhibition at 100 mM.This suggests that acetic acid production is a key factor in Fusarium suppression.Application of L. brevis to Fusarium-contaminated soil suppressed Fusarium disease in Japanese mustard spinach (Komatsuna) for up to 14 days.Collectively, these findings suggest that L. brevis has the potential to effectively suppress Fusarium disease without the need for chem. pesticides, thereby supporting environmentally friendly agricultural practices.

2025-03-05·Journal of Epidemiology

Validity and Reproducibility of Food Group Intakes in a Self-administered Food Frequency Questionnaire for Genomic and Omics Research: The Tohoku Medical Megabank Project

Article

作者: Maruya, Sachiko ; Obara, Taku ; Matsuno, Tomoka ; Murakami, Keiko ; Yamashita, Takahiro ; Aizawa, Misato ; Hoshina, Yuchie ; Yonezawa, Yudai ; Yamamoto, Masayuki ; Ogino, Mako ; Kuriyama, Shinichi ; Ishikuro, Mami ; Ishihara, Junko ; Takachi, Ribeka ; Takahashi, Ippei ; Noda, Aoi ; Nakadate, Misako ; Sugawara, Shiori ; Suzuki, Shigenori ; Kito, Kumiko

BACKGROUNDThe Tohoku Medical Megabank Project (TMM) was established to realize personalized healthcare and medicine using genomic and omics data. This study evaluated the validity and reproducibility of food group intakes derived from a self-administered food frequency questionnaire (TMM-FFQ) that included the response option "constitutionally unable to eat/drink it" among community-dwelling Japanese adults.METHODSParticipants comprised 89 men and 124 women aged ≥20 years from Miyagi Prefecture. Participants completed weighed food records (WFRs) for 3 consecutive days per season as reference intake and FFQs in 2019 (FFQ1) and 2021 (FFQ3). Spearman's rank correlation coefficients (CCs) were calculated for correlations between food group intakes estimated from the 12-day WFR and FFQ3 (validity), and for correlations between those estimated from the FFQ1 and FFQ3 (reproducibility). Cross-classification according to quintiles using FFQ and WFR data was also performed.RESULTSThe percentage of participants who chose the "constitutionally unable to eat/drink it" option was non-negligible for some food groups. In the validity analysis, CCs were >0.40 for many food groups; the median across 21 food groups was 0.49 in men and 0.45 in women. The median percentages of cross-classification into exact plus adjacent quintiles were 73.0% in men and 66.9% in women. In the reproducibility analysis, CCs were >0.50 for many food groups; the median across 21 food groups was 0.60 in men and 0.51 in women.CONCLUSIONThe validity of the TMM-FFQ compared with 12-day WFR and the reproducibility of the TMM-FFQ were reasonable for food groups in the TMM cohort studies.

2024-06-01·Breeding Research

Advances and perspectives of genetics and breeding in Brassicaceae crops