This study aims to evaluate a novel diet for adult Crohn's disease patients (The Crohn's Disease Exclusion Diet - CDED). Some of the patients in this study will receive the CDED combined with partial enteral nutrition (PEN), while the other group will receive the CDED with early introduction of dairy products, that were eliminated from the initial CDED protocol.

开始日期2024-03-10

申办/合作机构

Evangelismos Hospital

[+1]

NCT06163937

/ CompletedN/AIIT

Examining the Acute Effects of Two Different Fruit Juices (Orange Juice and Mixed Fruit Juice Consisted of Apple, Orange, Grape, and Pomegranate) on Postprandial Glycemic Responses and Satiety in Healthy Individuals

This study investigated the acute effects of two fruit juices on postprandial glycemic responses and satiety in healthy individuals

开始日期2023-09-01

申办/合作机构

Agricultural University of Athens

NCT05866744

/ CompletedN/AIIT

Effects of a Time-restricted Hypocaloric Mediterranean Diet in Patients with Non-alcoholic Fatty Liver Disease on Glucose Metabolism (CHRONO-NAFLD Project)

The effects of a time-restricted hypocaloric Mediterranean type diet compared to a conventional hypocaloric Mediterranean type diet on blood glucose metabolism and liver steatosis in people with non-alcoholic fatty liver disease will be investigated.

开始日期2023-05-08

申办/合作机构

Agricultural University of Athens

100 项与 Agricultural University of Athens 相关的临床结果

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0 项与 Agricultural University of Athens 相关的专利（医药）

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8,662

项与 Agricultural University of Athens 相关的文献（医药）

2025-12-31·Italian Journal of Animal Science

Nutritional, phenolic and in vitro digestion characteristics of dried grape pomace processed with different micronization/air-classification protocols

作者: Casalino, Elisabetta ; Blando, Federica ; Tsiplakou, Eleni ; Maggiolino, Aristide ; De Palo, Pasquale ; Greco, Roberta

Micronization and air-classification enhance grape pomace, creating high-value feed ingredients and reducing agro-industrial waste.Fine fractions provide protein-rich supplements; coarse fractions offer fiber for sustainable animal feed applications.Processing grape pomace supports circular economy by transforming waste into cost-effective, functional feed solutions

2025-12-15·Animal Biotechnology

Nutrigenomic evidence of phytogenic cytoprotective functions in the ovary and liver provides mechanistic support for improved laying hen performance

Article

作者: Mountzouris, Konstantinos C. ; Brouklogiannis, Ioannis

The study assessed the inclusion level effects of a phytogenic blend (PB) on performance and critical molecular biomarkers related to detoxification (Aryl hydrocarbon receptor; AhR) and antioxidant (Nuclear factor-erythroid 2-related factor 2; Nrf2) responses in layers' ovary and liver. Layers (n = 385; 21-week-old; Hy-Line Brown) were allotted to 5 treatments with 7 replicates of 11 hens each, for a 12-week feeding trial. Treatments were: control (CON) without PB or supplementation with PB at 250 (PB250), 750 (PB750), 1000 (PB1000) and 1500 mg/kg diet (PB1500), respectively. Performance was determined weekly for the 12-week experimental period. At the 6^th and 12^th experimental week ovarian and liver samples were collected for gene expression analysis. Increasing PB inclusion level, improved linearly and quadratically overall laying rate, egg mass and FCR, with optimal (P ≤ 0.001) performance notable in the PB750 compared to CON. The nutrigenomic analysis revealed that PB inclusion resulted (P ≤ 0.05) in consistent beneficial modulation of the AhR/Nrf2 pathway-related genes assessed at the 6^th and 12^th experimental week, both in the ovary and the liver of laying hens. In conclusion, PB beneficially modulated the ovarian and hepatic adaptive cytoprotection and supported the laying performance improvements recorded, with PB750 displaying the optimal benefits.

2025-09-01·Food Microbiology

VBNC induction and persistence of Listeria monocytogenes Scott A as a defence mechanism against free chlorine stress

Article

作者: Balomenos, Athanasios ; Skandamis, Panagiotis ; Tsakanikas, Panagiotis ; Arvaniti, Marianna

Sodium hypochlorite (SH) belongs to the chlorine-releasing agents (CRAs) and is widely used as a disinfectant or a bleaching agent for sanitizing in the food processing environment and fresh-cut industry. In the present study, the potential induction of dormancy states, i.e. the VBNC state and persistence, in Listeria monocytogenes, Scott A strain, was evaluated after exposure to SH for 3 h at 20 °C. Our results showed that the concentration of free chlorine after cells (10^9.5 CFU/mL) resuspension into the working solution decreased down to 3.7 ppm (SD ± 0.4 ppm; pH 6.64 ± 0.1). To detect VBNC fractions we evaluated comparatively the results of plate counting with fluorescence microscopy, using 5(6)-carboxy-fluorescein diacetate (CFDA; metabolic activity) and propidium iodide (PI; death) staining. The resuscitation capacity of L. monocytogenes stressed single cells was monitored real-time on TSAYE at 37°C, using time-lapse microscopy. Thus, colony outgrowth kinetics were estimated and non-diving fractions were detected. Furthermore, variability in the division time per generation was examined. Our analyses showed that SH induces the VBNC state and persistence in L. monocytogenes. Phenotypic variants of "high" fitness, i.e. size colony variations (SCVs) were also detected in response to SH stress. L. monocytogenes cells presented a prolonged lag time after exposure to SH. This phenomenon is a defence mechanism that allows cells to tolerate stress and maximize population fitness. The investigation of the VBNC state is of high importance for the food industry, as the impacts of VBNC induction and single cell outgrowth heterogeneity can contribute to false-negative detection outcomes.

100 项与 Agricultural University of Athens 相关的药物交易

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100 项与 Agricultural University of Athens 相关的转化医学

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