University Hospital of Montpellier

Châtillon, France, May 30, 2024 DBV Technologies to Participate in Upcoming EAACI 2024 Congress DBV Technologies (Euronext: DBV – ISIN: FR0010417345 – Nasdaq Stock Market: DBVT), a clinical-stage biopharmaceutical company focused on treatment options for food allergies and other immunologic conditions with significant unmet medical need, today announced its upcoming participation in the European Academy of Allergy and Clinical Immunology (EAACI) Congress May 31 – June 3 in Valencia, Spain. A flash talk presentation by Nicolette Arends, M.D., Erasmus University Rotterdam will describe data collected on accidental peanut consumption from DBV’s EPITOPE Phase 3 study and its ongoing open-label extension study in peanut-allergic toddlers aged 1 through 3 years. DBV will also host a symposium and exhibit booth in the EAACI exhibit hall. “We are deeply committed to establishing long-term safety and clinical data of Viaskin Peanut in the pediatric population, which includes examining reactions that occur during accidental consumption,” said Daniel Tassé, Chief Executive Officer of DBV Technologies. “While avoidance is the first line of defense, the reality is an accidental exposure is likely, necessitating approved treatment options that can help provide protection.” “We track accidental peanut consumption in our clinical studies to better understand how epicutaneous immunotherapy with Viaskin Peanut may help reduce the risk of an allergic reaction over time,” said Pharis Mohideen, M.D. Chief Medical Officer at DBV Technologies. “Analyzing accidental peanut consumption exposure better characterizes the real-world clinical benefit that Viaskin Peanut may provide if approved.” DBV’s symposium, “Epicutaneous Route: An Innovative Potential Approach to Food Immunotherapy”, will be moderated by Stefania Arasi, M.D., Ph.D., MSc., Pediatric Allergist and Researcher at Paediatric Allergy Unit, Bambino Gesù Children Research Hospital, Rome, Italy and current EAACI Pediatric Section Chair and Philippe Eigenmann, M.D., Pediatric Allergist and Head of Pediatric Allergy Unit at the Geneva University Hospital, Geneva, Switzerland. It will include lectures by Luciana Tanno, M.D., Ph.D. Allergist, Division of Allergy, University Hospital of Montpellier, Montpellier, France on potential clinical applications of the epicutaneous route, and Pablo Rodríguez del Río, M.D., Ph.D., Allergist Hospital Infantil Universitario Niño Jesús, Department of Allergy, Madrid, Spain, on most recent results and perspectives of the epicutaneous route in peanut allergy, respectively. DBV will host a booth (F10) in the exhibit hall where attendees can learn more about epicutaneous immunotherapy with Viaskin, including our ongoing clinical trials in peanut-allergic children. Flash Talk Presentation Details “Reactions Due to Accidental Peanut Consumption During Epicutaneous Immunotherapy for Peanut Allergy in Toddlers” presented by Nicolette Arends, M.D. Researcher, Pediatrics Erasmus University Medical Center, Rotterdam, Netherlands Session title: Flash Talks on PediatricsSession number: FT 15Session date: Sunday, June 2, 2024Session time: 8:30 a.m. – 10:30 a.m. CET A voice-recording of the onsite flash talk presentation will be made available on the congress platform. A copy of the poster will be made available after the presentation on the Scientific Publications & Presentations page on the Our Science section of the Company’s website www.dbv-technologies.com. Symposium “Epicutaneous route: An innovative potential approach to food immunotherapy” will be moderated by Stefania Arasi and Philippe Eigenmann Date and location: Saturday, June 1, 12:00 – 1:00 p.m. CEST, Malaga RoomLectures: Introduction- Dr. Stefania ArasiThe epicutaneous route: from the concept to potential clinical applications- Dr. Luciana Tanno The epicutaneous immunotherapy for peanut allergy: most recent results and perspectives- Dr. Pablo Rodríguez del RíoConclusion- Dr. Philippe Eigenmann About DBV TechnologiesDBV Technologies is a clinical-stage biopharmaceutical company developing treatment options for food allergies and other immunologic conditions with significant unmet medical need. DBV is currently focused on investigating the use of its proprietary technology platform, Viaskin™, to address food allergies, which are caused by a hypersensitive immune reaction and characterized by a range of symptoms varying in severity from mild to life-threatening anaphylaxis. Millions of people live with food allergies, including young children. Through epicutaneous immunotherapy (EPIT™), the Viaskin platform is designed to introduce microgram amounts of a biologically active compound to the immune system through intact skin. EPIT is a new class of non-invasive treatment that seeks to modify an individual’s underlying allergy by re-educating the immune system to become desensitized to allergen by leveraging the skin’s immune tolerizing properties. DBV is committed to transforming the care of food allergic people. The Company’s food allergy programs include ongoing clinical trials of Viaskin Peanut in peanut allergic toddlers (1 through 3 years of age) and children (4 through 7 years of age). DBV Technologies is headquartered in Châtillon, France, with North American operations in Warren, NJ. The Company’s ordinary shares are traded on segment B of Euronext Paris (Ticker: DBV, ISIN code: FR0010417345) and the Company’s ADSs (each representing one-half of one ordinary share) are traded on the Nasdaq Stock Market (Ticker: DBVT). For more information, please visit www.dbv-technologies.com and engage with us on X (formerly Twitter) and LinkedIn. Forward Looking StatementsThis press release may contain forward-looking statements and estimates, including, but not limited to, statements regarding the therapeutic potential of Viaskin™ Peanut and EPIT™ and DBV’s planned regulatory and clinical efforts including timing and results of communications with regulatory agencies, and the ability of any of DBV’s product candidates, if approved, to improve the lives of patients with food allergies. These forward-looking statements and estimates are not promises or guarantees and involve substantial risks and uncertainties. At this stage, DBV’s product candidates have not been authorized for sale in any country. Among the factors that could cause actual results to differ materially from those described or projected herein include uncertainties associated generally with research and development, clinical trials and related regulatory reviews and approvals, and DBV’s ability to successfully execute on its budget discipline measures. A further list and description of risks and uncertainties that could cause actual results to differ materially from those set forth in the forward-looking statements in this press release can be found in DBV’s regulatory filings with the French Autorité des Marchés Financiers (“AMF”), DBV’s filings and reports with the U.S. Securities and Exchange Commission (“SEC”), including in DBV’s Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 7, 2024, and future filings and reports made with the AMF and SEC by DBV. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements and estimates, which speak only as of the date hereof. Other than as required by applicable law, DBV Technologies undertakes no obligation to update or revise the information contained in this Press Release. Viaskin and EPIT are trademarks of DBV Technologies. Investor Contact Katie MatthewsDBV Technologieskatie.matthews@dbv-technologies.com Media ContactAngela MarcucciDBV Technologiesangela.marucci@dbv-technologies.com Attachment PDF Version

Coordinated by Montpellier University Medical Center, France, the international study IN EXTREMIS-LASTE, representing a groundbreaking contribution to stroke research was published today in the New England Journal of Medicine.MONTPELLIER, France, May 9, 2024 /PRNewswire/ -- "LASTE" ( LArge Stroke Therapy Evaluation), a prospective, randomized, controlled trial co-led by Professor Vincent Costalat (neuroradiologist, Montpellier, France) and Dr. Caroline Arquizan (vascular neurologist, Montpellier, France), in addition to Dr. Bertrand Lapergue (vascular neurologist, Hospital Foch, Paris, France) and Prof. Tudor Jovin (interventional and vascular neurologist, Cooper University Hospital, Camden, NJ, USA) has the potential to disrupt current systems of care involving triage and management of patients with acute stroke due to large vessel occlusion by demonstrating that even those patients with the largest areas of "irreversibly" damaged brain as assessed by state-of-the-art imaging technologies still benefit from mechanical reperfusion. Continue Reading From letf to right, Caroline Arquizan, MD, Chief of Neurovascular Department of University Hospital of Montpellier, France, Vincent Costalat, MD, PhD, Professor of Radiology and Chief of Neuroradiology Department of University Hospital of Montpellier, France Prof. Tudor Jovin, Chair of the Neurology Department of Cooper University Medical Center in Camden, New Jersey, USA Bertrand Lapergue, MD, PhD, Chief of Neurology and Neurovascular Department from Hospital Foch in Paris, France Illustration of LASTE clinical trial learnings – Brain parts that brain imaging suggests is dead may not entirely be so. Vincent Costalat, MD, PhD, Professor of Radiology and Chief of Neuroradiology Department of University Hospital of Montpellier, France Les enseignements de l’étude LASTE – Les parties du cerveau que l’on croyait détruites d’après les imageries cérébrales ne le sont pas entièrement. Vincent Costalat, MD, PhD, Professor of Radiology and Chief of Neuroradiology Department of University Hospital of Montpellier, France Trial of Thrombectomy for Stroke with a Large Infract of Unrestrited Size, published in the New England Journal of Medicine Since mechanical thrombectomy, a technique that aims to restore blood flow in stroke patients who experience sudden occlusion of a brain artery, by removing the blockage with device-based technologies, became standard of care in 2015, physicians selected for such intervention only stroke patients who displayed limited amounts of brain damage on brain imaging. This was based on the principle that restoration of blood flow to large areas of irreversibly damaged brain is not only futile but can also cause additional damage due to an increased risk of bleeding in the brain among other detrimental effects of reperfusion. Yet, an international network of stroke centers led by the Montpellier University Hospital investigators has proven the opposite. The multicenter therapeutic trial "LASTE" was conducted in France (26 centers) and Spain (7 centers) for 3 years. The trial aimed to select patients hitherto considered "irrecoverable" in common practice due to unrestrictedly large areas of irreversibly compromised brain presenting with acute stroke due to large vessel occlusion within 7 hours of stroke onset to test the hypothesis that reperfusion of brain tissue considered dead could improve their outcome not only in term of survival but also in terms of functional recovery.IN EXTREMIS TRIALS LASTE and MOSTE are sponsored by an Industrial unrestricted grant co-founded by 5 industrial partners (BALT, CERENOVUS, MEDTRONIC, MICROVENTION, STRYKER).Photo: Photo: Logo: Contacts : [email protected] [email protected] SOURCE CHU de Montpellier

FRIDAY, April 21, 2023 -- For adults with radiologically isolated syndrome (RIS), teriflunomide is associated with a reduction in the first clinical demyelinating event compared with placebo, according to a study presented at the annual meeting of the American Academy of Neurology, held from April 22 to 27 in Boston. Christine Lebrun Frenay, M.D., from the University Hospital of Nice in France, and colleagues randomly assigned 89 patients with RIS to teriflunomide or placebo in a phase III study. Participants underwent follow-up at weeks 48 and 96. The researchers detected 28 clinical events during follow-up (20 with placebo; eight with teriflunomide). The superiority of teriflunomide was demonstrated in unadjusted and adjusted analyses (hazard ratios, 0.38 and 0.34, respectively). The teriflunomide arm had a reduction in the number of patients with gadolinium+ lesions and the cumulative number of new or enlarging T2 lesions, although these results were not statistically significant. "Our findings suggest that early intervention with teriflunomide may be beneficial to those diagnosed with radiologically isolated syndrome, the presymptomatic phase of multiple sclerosis," Lebrun Frenay said in a statement. "However, more research is needed in larger groups of people to confirm our findings. Additionally, it is important that medical professionals are cautious when using MRI expertise to diagnose this condition, selecting only patients at risk of developing multiple sclerosis and not increasing MRI misdiagnoses." The study was funded by Sanofi, which manufactures teriflunomide. Press Release More Information Posted April 2023