Fondazione Policlinico Universitario Campus Bio-Medico

Goal: The clinical investigation involves the evaluation of the usability level of the VR system, sense of presence, and co-presence during the execution of various rehabilitation exercises through specific questionnaires.
Participant Population: The study will enroll 50 patients with shoulder musculoskeletal disorders will be enrolled
Main Questions:
* How does the integration of Virtual Reality (VR) in rehabilitation programs impact the usability of the system for patients with shoulder musculoskeletal disorders?
* To what extent does the sense of presence experienced by patients using VR systems influence their motivation and adherence to rehabilitation exercises?
* How do patients with shoulder musculoskeletal disorders perceive the co-presence in VR rehabilitation scenarios, and how does it affect their overall treatment experience?
Participant Tasks:
* Shoulder Physical Examination
* Instructions to the patient on exercises to be performed using Oculus and selection of customizable settings on the VR app
* Execution of the protocol developed for shoulder rehabilitation in a virtual environment
* Evaluation of the usability of the VR system, sense of presence, and co-presence through different validated scales

Goal: The clinical investigation aims to evaluate the usability of passive exoskeletons, their impact on daily living activities, and the perceived experience of patients with shoulder musculoskeletal disorders. This will be assessed through specific validated questionnaires.
Participant Population: The study will enroll 15 participants diagnosed with shoulder musculoskeletal disorders, including rotator cuff tears, adhesive capsulitis, and glenohumeral osteoarthritis. Participants must be employed in physically demanding jobs that require frequent upper limb activity.
Main Questions:
* How does the integration of passive exoskeletons in daily activities influence usability and functional performance in patients with shoulder musculoskeletal disorders?
* To what extent does the use of passive exoskeletons improve the perceived physical effort and quality of life in these patients?
* How do patients perceive the comfort and effectiveness of passive exoskeletons during the execution of daily living tasks?
Participant Tasks:
* Comprehensive shoulder physical examination. Instruction on the proper use of the Paexo passive exoskeleton and customization of its settings.
* Execution of workplace-relevant tasks (e.g., lifting, overhead reaching) with and without the exoskeleton.
* Evaluation of usability, comfort, and perceived workload using validated scales such as the System Usability Scale (SUS), NASA Task Load Index (NASA-TLX), and Technology Acceptance Model (TAM).

Soft tissue sarcomas are a group of rare and heterogeneous tumors. Surgery is the mainstay of treatment and microscopic negative margins need to be achieved to improve disease local control. We designed this prospective study to evaluate the main features of motor impairment and the impact of tailored robotic rehabilitation techniques in patients treated for localized soft tissue sarcoma (surgery alone, or surgery + radiation or radiochemotherapy). Specific patients' motor strategies will be quantitatively measured through a biomechanical assessment, including the analysis of joint kinematics, and muscle activity timing patterns. Considering the influence of motor impairment after demolitive surgery, a major interest of this study will be focused on nutrition and Quality of life which will be prospectively evaluated by specific questionnaires at different time points.