Chongqing Aier Eye Hospital Co., Ltd. (重庆爱尔眼科医院有限公司)

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13

项与重庆爱尔眼科医院有限公司相关的临床试验

ChiCTR2300078676 / Suspended早期临床1期

study on the safe and efficient of femtosecond laser assisted cataract surgery with high myopia

开始日期2023-12-31

申办/合作机构

重庆爱尔眼科医院有限公司

ChiCTR2300078628 / Suspended

Ocular photobiomodulation therapy for visual rehabilitation after retinal detachment surgery

开始日期2023-12-30

申办/合作机构

重庆爱尔眼科医院有限公司

ChiCTR2100052791 / RecruitingN/A

A prospective multicenter registry study of visual performance after PanOptix implantation in both eyes

开始日期2021-11-15

申办/合作机构

重庆爱尔眼科医院有限公司

100 项与重庆爱尔眼科医院有限公司相关的临床结果

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0 项与重庆爱尔眼科医院有限公司相关的专利（医药）

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32

项与重庆爱尔眼科医院有限公司相关的文献（医药）

2024-09-01·Cell and Tissue Banking

Comparison of the structural integrity and quality of corneal endothelium stored in organ culture storage medium versus Eusol-C

Article

作者: Zhu, Meidong ; Gao, Yang ; Liu, Yonghuan ; Zhou, Qizhi ; Zhang, Ming ; Ren, Yi ; Wang, Qin ; Hu, Jian ; Yang, Lihong

In this experimental study, we compared the structural integrity and cell quality of corneal endothelium stored in organ culture medium (OCS) and Eusol-C. The experiment included rabbit and human cornea experiments in vitro. Thirty rabbit corneas and thirty-two human corneas were collected and divided into two groups. All right corneas were allocated in experiment group and left corneas were placed in control group. The corneas in experimental group were stored in OCS at 34 °C, and the corneas in control group were stored in Eusol-C at 4 °C for 7, 14, 21, 28, and 35 days, respectively. Endothelial cell morphology, cell count, and trypan blue staining for viability were assessed before storage (Day 0) and at days 7, 14, 21, 28 and 35. The structural integrity of human corneal endothelial cell was analyzed using immunohistochemistry. The samples of storage solution for microbial culture were collected on the third day and at the end of storage. The results show that no bacterial and fungal infections were found in both groups. After 14 days of storage, the morphology of endothelial cell was better in the experimental group than in the control group. The endothelial cell stored in OCS were better than those stored in Eusol-C at the end of storage times, except human cornea 14 days storage group. The ZO-1 protein staining showed the typical polygonal morphology of endothelial cell stored in the OCS. Corneal endothelial cells stored in the OCS had better quality up to 28 days. It can be applied to Chinese eye banks as a method of corneal preservation.

2024-02-02·Medicine

Clinical efficacy of subthreshold micropulse laser combined with anti-VEGF drugs in the treatment of diabetic macular edema: A meta-analysis

Article

作者: Zhu, Ting ; Chen, Mei ; Xu, Dahua ; Huang, Lin ; Wang, Xiaolin

Background:To systematically evaluate the efficacy and safety of subthreshold micropulse laser (SML) combined with anti-vascular endothelial growth factor (VEGF) drugs for the treatment of diabetic macular edema (DME).Methods:The randomized controlled trials on SML combined with anti-VEGF drugs for DME were retrieved from China National Knowledge Infrastructure, Wan Fang Data, VIP Data, Sino Med (China Biomedical Literature Database), PubMed, Web of Science, The Cochrane Library, and Embase by computer from inception to April 19, 2022. The observation group was treated with SML combined with anti-VEGF drugs, while the control group was treated with anti-VEGF agents alone or SML. And the references of the included literature were manually searched. The Meta-analysis was performed using Revman 5.4 and STATA SE 15.Results:This study finally included 15 randomized controlled trials involving 891 eyes for Meta-analysis. The results showed that there was no statistically significant difference between the 2 groups in best-corrected visual acuity at 1, 3, 6, 9, and 12 months after treatment. There was no statistical difference between the 2 groups in central macular thickness (CMT) at 1, 3, and 6 months after treatment (P > .05). CMT in the observation group was lower than that in the control group at 9 and 12 months (P < .05). There was no statistical difference between the 2 groups in total macular volume at 3, 6, 9, and 12 months in CMT (P > .05). The number of anti-VEGF drugs injections in the observation was lower than that in the control group (P < .05). The occurrence of complications between the 2 groups was not statistically significant difference (P > .05).Conclusion:SML in combination with anti-VEGF drugs in patients with DME are comparable in reducing the number of anti-VEGF drugs injections and CMT, thereby reducing the financial burden on patients. It does not differ in best-corrected visual acuity and total macular volume.

2023-10-01·Journal francais d'ophtalmologie

Central serous chorioretinopathy complicated by uveal effusion syndrome: Case report.

Letter

作者: Chen, M ; Xu, D

100 项与重庆爱尔眼科医院有限公司相关的药物交易

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100 项与重庆爱尔眼科医院有限公司相关的转化医学

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