Delving into the Latest Updates on Tianjin Eye Hospital with Synapse

概览

排名前五的药物类型	数量

蛋白类药物	1

排名前五的靶点	数量

Akt x PI3K family	1

关联

1

项与 Tianjin Eye Hospital 相关的药物

Cocaine and amphetamine-regulated transcript(Nankai University)

靶点

Akt x PI3K family

作用机制

Akt 刺激剂 [+1]

在研机构

Tianjin Eye Hospital [+1]

原研机构-

在研适应症

心肌再灌注损伤

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

130

项与 Tianjin Eye Hospital 相关的临床试验

ChiCTR2400090718 / SuspendedN/AIIT

Observation and Experiment on the Effect of Controlling Myopia Growth with Gemini multi-point non-equal Lens

开始日期2024-11-01

申办/合作机构

Tianjin Eye Hospital

ChiCTR2400088686 / RecruitingN/AIIT

A prospective, multicenter, randomized, open label, parallel positive controlled clinical study evaluating the effectiveness and safety of hydrogen peroxide contact lens care solution for contact lens wearers

开始日期2024-08-09

申办/合作机构

Tianjin Eye Hospital

ChiCTR2400084981 / SuspendedN/AIIT

Research on the Development of PS-SS-OCT Measurement System

开始日期2024-05-29

申办/合作机构

Tianjin Eye Hospital

100 项与 Tianjin Eye Hospital 相关的临床结果

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0 项与 Tianjin Eye Hospital 相关的专利（医药）

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658

项与 Tianjin Eye Hospital 相关的文献（医药）

2024-12-01·JPRAS Open

Comparative evaluation of conventional and modified Hughes procedures in reconstructing large full-thickness defects of the lower eyelid

Article

作者: Li, Jiagen ; Zhao, Hong ; Zhang, Lei ; Pan, Ye

PurposeTo introduce a modified Hughes procedure for the repair of large full-thickness defects of the lower eyelid.MethodsThis retrospective study included 56 patients: 30 in the conventional group treated with a Hughes flap and 26 in the modified group treated with a full-thickness upper eyelid flap pedicled with levator aponeurosis, Muller muscle and conjunctiva. The reconstruction time, period of pedicle division and complication rates were evaluated.ResultsThe lower eyelid reconstruction time was 89.2±7.7 minutes in the conventional group and 61.7±7.5 minutes in the modified group, whereas the period of pedicle division was 21.1±3.0 days in the conventional group and 10.8±3.0 days in the modified group, and the differences were statistically significant (p = 0.000 and 0.000). Lower eyelid retraction was 0.4±0.4 mm in the conventional group and 0.1±0.2 mm in the modified group, and the difference was statistically significant (p = 0.001).ConclusionThe modified Hughes procedure in this study resulted in a shorter lower eyelid reconstruction time, a shorter period of pedicle division, and a lower degree of lower eyelid retraction. This technique is simple and convenient for reconstructing large full-thickness defects of the lower eyelid.

2024-11-01·British Journal of Ophthalmology

One-year efficacy of myopia control by the defocus distributed multipoint lens: a multicentric randomised controlled trial

Article

作者: Wu, Min ; Li, Mengdi ; Li, Jun ; Wang, Yansong ; Guo, Xingyi ; Li, Lihua ; Wang, Yan ; Yu, Cui ; Lu, Wenli ; Wang, Yanbo ; Chen, Xiaoqin ; Liu, Xiaonan

AimsTo report the 1-year results of the efficacy of a defocus distributed multipoint (DDM) lens in controlling myopia progression in a multicentre, randomised controlled trial.MethodsOverall, 168 children aged 6–13 years were recruited and randomly assigned to wear a DDM lens (n=84) or single-vision (SV) lens (n=84) in three centres. Cycloplegic autorefraction (spherical equivalent refraction (SER)) and axial length (AL) were measured. Linear mixed model analysis was performed to compare between-group SER and AL changes. Logistic regression analysis was used to analyse the between-group difference in rapid myopia progression (SER increase≥0.75 D per year or AL growth≥0.40 mm per year).ResultsAfter 1 year, mean changes in SER were significantly lower in the DDM group (−0.47±0.37 D) than in the SV group (−0.71±0.42 D) (p<0.001). Similarly, mean changes in AL were significantly lower in the DDM group (0.21±0.17 mm) than in the SV group (0.34±0.16 mm) (p<0.001). After adjusting for age, sex, daily wearing time and parental myopia, rapid myopia progression risk was higher in the SV group than in the DDM group (OR=3.51, 95% CI: 1.77 to 6.99), especially for children who wore a lens for >12 hours per day, boys and younger children (6–9 years) with ORs (95% CIs) of 10.82 (3.22 to 36.37), 5.34 (1.93 to 14.78) and 8.73 (2.6 to 29.33), respectively.ConclusionsAfter 1 year, DDM lenses effectively retarded myopia progression in children. Longer daily wearing time of DDM lens improved the efficacy of myopia control. Future long-term studies are needed for validation.Trial registration numberNCT05340699 .

2024-09-18·International Journal of Ophthalmology

Single self-leading suture technique for iridodialysis repairment

Article

作者: Tang, Yong ; Wang, Ying ; Hui, Jing-Wen ; Han, Quan-Hong ; Wang, Ying ; Tang, Yong

100 项与 Tianjin Eye Hospital 相关的药物交易

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100 项与 Tianjin Eye Hospital 相关的转化医学

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