Shenyang Aier Eye Hospital Co., Ltd. (沈阳爱尔眼科医院有限公司)

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21

项与沈阳爱尔眼科医院有限公司相关的临床试验

ChiCTR2400083061 / SuspendedN/A

pseudophakic accommodation of intraocular crystals and analysis of related factors

开始日期2024-04-15

申办/合作机构

沈阳爱尔眼科医院有限公司

ChiCTR2300070802 / SuspendedN/A

Observation of visual effects after regional refraction depth-of-field extension intraocular lens implantation

开始日期2023-04-24

申办/合作机构

沈阳爱尔眼科医院有限公司

ChiCTR2300068881 / SuspendedN/A

Accuracy and Consistency of Different Ocular Blood Flow Detection Methods

开始日期2023-03-01

申办/合作机构

沈阳爱尔眼科医院有限公司

100 项与沈阳爱尔眼科医院有限公司相关的临床结果

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0 项与沈阳爱尔眼科医院有限公司相关的专利（医药）

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29

项与沈阳爱尔眼科医院有限公司相关的文献（医药）

2023-08-01·American journal of ophthalmology

Detection of Keratoconus With a New Corvis Biomechanical Index Optimized for Chinese Populations.

Article

作者: Vinciguerra, Paolo ; Chen, Shihao ; Zhou, Xingtao ; Wang, Yan ; Bai, Ji ; Vinciguerra, Riccardo ; Ambrosio, Renato ; Yu, Keming ; Zhang, Fengju ; Fang, Xuejun

PURPOSEThe aim of this study was to introduce an optimized version of the Corvis Biomechanical Index for Chinese populations (cCBI).DESIGNRetrospective, multicenter clinical validity enhancement study.METHODSPatients were included from 7 clinics in Beijing, Shenyang, Guangzhou, Shanghai, Wenzhou, Chongqing, and Tianjin, China. Logistic regression was used to optimize the values of the constants of the CBI, based on database 1 as the development dataset (6 of 7 clinics), to create a new version of the index named cCBI. The factors of the CBI (A1Velocity, ARTh, Stiffness Parameter-A, DARatio2mm, and Inverse Integrated Radius) and the cutoff value were kept the same (0.5). With the formation of cCBI determined, it was validated on database 2 (1 of the 7 clinics).RESULTSTwo thousand four hundred seventy-three patients (healthy and keratoconus) were included. In database 2, the area under the curve of the cCBI was 0.985 with 93.4% specificity and 95.5% sensitivity. In the same dataset, the original CBI produced an area under the curve of 0.978 with 68.1% specificity and 97.7% sensitivity. There was a statistically significant difference between the receiver operating characteristic curve of cCBI and CBI (De Long P = .0009) CONCLUSION: The new cCBI for Chinese patients was shown to be statistically significantly better when compared with CBI to separate healthy from keratoconic eyes. The presence of an external validation dataset confirms this finding and suggests the use of cCBI in everyday clinical practice to aid in the diagnosis of keratoconus in patients who are of Chinese ethnicity.

2023-05-01·Ophthalmology

The Efficacy of Defocus Incorporated Multiple Segments Lenses in Slowing Myopia Progression

Article

作者: Huang, Dan ; Yang, Zhikuan ; Lu, Yiqiu ; Lan, Weizhong ; Fan, Chunlei ; Li, Xiaoning ; Wang, Qinqin ; Chen, Chunmei ; Yang, Jiwen ; Liu, Jiaxin ; Jiang, Hongyan ; Li, Jianhua ; Li, Shan ; Jiang, Baolin

PURPOSEDefocus incorporated multiple segments (DIMS) spectacle lenses were reported to slow myopia progression significantly in a randomized controlled trial (RCT). The study evaluated their effectiveness in clinical settings.DESIGNRetrospective study.PARTICIPANTSPatient records involving use of DIMS and single-vision (SV) spectacle lenses were collected from subsidiary hospitals of Aier Eye Hospital Group.METHODSThe spherical equivalent (SE), determined by subjective refraction, was adopted to assess the myopia progression. The strategy of propensity score matching (PSM) was applied to match the confounding baseline characteristics between the 2 groups. The effectiveness was calculated based on the difference of myopia progression of these 2 approaches.MAIN OUTCOME MEASURESChange in SE.RESULTSThree thousand six hundred thirty-nine patients with DIMS and 6838 patients with SV spectacles were included. The age of the patients was 6 to 16 years (mean ± standard deviation: 11.02 ± 2.53 years). The baseline SE was between 0.00 and -10.00 diopters (D) (mean ± standard deviation: -2.78 ± 1.74 D). After the PSM, data on 2240 pairs with 1-year follow-up and on 735 pairs with 2-year follow-up were obtained. Significantly slower progression was seen in the DIMS group at both the 1-year (DIMS, -0.50 ± 0.43 D; SV, -0.77 ± 0.58 D; P < 0.001) and 2-year (DIMS, -0.88 ± 0.62 D; SV, -1.23 ± 0.76 D; P < 0.001) subdataset. In the 1-year subdataset, 40% and 19% showed myopia progression of no more than 0.25 D for the DIMS and SV groups, respectively (chi-square, 223.43; P < 0.001), whereas 9% and 22% showed myopia progression of more than 1.00 D for the DIMS and SV groups, respectively (chi-square, 163.38; P < 0.001). In the 2-year subdataset, 33% and 20% showed myopia progression of no more than 0.50 D for the DIMS and SV groups, respectively (chi-square, 31.15; P < 0.001), whereas 12% and 29% showed myopia progression of more than 1.50 D for the DIMS and SV groups (chi-square, 65.60; P < 0.001).CONCLUSIONSAlthough the magnitude was lower than that reported in the previous RCT, this large-scale study with diversity of the data sources confirmed the effectiveness of DIMS spectacles to slow myopia progression in clinical practice.FINANCIAL DISCLOSURE(S)Proprietary or commercial disclosure may be found after the references.

2023-03-01·Graefe's Archive for Clinical and Experimental Ophthalmology

Response to: Clinical results of topography-guided laser-assisted in situ keratomileusis using the anterior corneal astigmatism axis and manifest refractive astigmatism axis

Letter

作者: Liu, Chunlei ; Wang, Yan

100 项与沈阳爱尔眼科医院有限公司相关的药物交易

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100 项与沈阳爱尔眼科医院有限公司相关的转化医学

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