Wuhan Aier Eye Hospital Co., Ltd. (武汉爱尔眼科医院有限公司)

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12

项与武汉爱尔眼科医院有限公司相关的临床试验

ChiCTR2400091422

/ Suspended临床4期

Clinical Study on the Efficacy Evaluation of Hypochlorous Acid in Patients with Blepharitis.

开始日期2024-11-01

申办/合作机构

武汉爱尔眼科医院有限公司

ChiCTR2400079680

/ RecruitingN/A

NAD+alleviates iron death induced by oxidative stress in fibrotic cataract

开始日期2022-12-01

申办/合作机构

武汉爱尔眼科医院有限公司

ChiCTR2100050448

/ RecruitingN/A

Vector Analysis of Astigmatism Corrected by TICL and TG-LASIK

开始日期2021-09-15

申办/合作机构

武汉爱尔眼科医院有限公司

100 项与武汉爱尔眼科医院有限公司相关的临床结果

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0 项与武汉爱尔眼科医院有限公司相关的专利（医药）

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66

项与武汉爱尔眼科医院有限公司相关的文献（医药）

2025-03-01·Contact Lens and Anterior Eye

Ocular surface side effects of botulinum toxin type A injections in the treatment of lateral canthal wrinkles (Crow’s Feet)

Article

作者: Tu, Huifang ; Ji, Ruiting ; Gong, Qianwen ; Yang, Xue ; Hu, Liang ; Han, Jiaxin ; Yang, Fan ; Lu, Xiulan ; Liu, Tingting

PURPOSEThis study investigates the impact of Botulinum Toxin Type A (BoNT-A) injections for lateral canthal wrinkles on the ocular surface.METHODSA total of 30 patients (30 eyes) who received BoNT-A injections were followed over a three-month period. Evaluations included tear meniscus height (TMH), strip meniscometry test, fluorescein tear film break-up time (FTBUT), corneal staining score, meibomian gland orifice and meibum quality score. Observations were recorded at baseline, one week, one month, and three months post-injection.RESULTSUpper and total eyelid meiboscore, meibomian gland orifice obstruction, and meibum quality score peaked at three months post-injection, while FTBUT was shortest during the same period, with significant differences observed across time points (P < 0.05). Post-hoc analysis indicated a significant reduction in FTBUT between baseline and three months (P = 0.048). Corneal staining scores were highest at one week, with significant differences across time points (P < 0.001); post-hoc analysis revealed a significant difference between one week and three months (P = 0.037). No significant changes were found in TMH or strip meniscometry test score (P = 0.374, P = 0.732).CONCLUSIONSBoNT-A injections may temporarily compromise ocular surface stability by decreasing tear film stability, disrupting meibomian gland function, and causing corneal epithelial disruption.

2025-01-20·Chinese Medical Journal

Ocular biometric characteristics of young Chinese people with axial lengths greater than 26.00 mm

Article

作者: Wang, Zheng ; Yao, Hui ; Wang, Wenjuan ; Huang, Chunli ; Li, Shaowei ; Zhou, Jihong ; Li, Xinxin ; Fang, Xuejun ; Zhang, Qingsong ; Cai, Jinfeng ; Zhu, Xiaoying

2025-01-01·Cell Reports Medicine

Enhancing AI reliability: A foundation model with uncertainty estimation for optical coherence tomography-based retinal disease diagnosis

Article

作者: Peng, Yuanyuan ; Luo, Jing ; Feng, Lixia ; Gao, Ling ; Liang, Zhen ; Liang, Dan ; Chen, Xinjian ; Lin, Aidi ; Wang, Meng ; Li, Tao ; Zou, Ke ; Shi, Tingkun ; Fu, Huazhu ; Liu, Linna ; Yu, Shanshan ; Chen, Haoyu ; Cheng, Ching-Yu ; Sun, Dawei ; Wu, Jianhua ; Lin, Tian

Inability to express the confidence level and detect unseen disease classes limits the clinical implementation of artificial intelligence in the real world. We develop a foundation model with uncertainty estimation (FMUE) to detect 16 retinal conditions on optical coherence tomography (OCT). In the internal test set, FMUE achieves a higher F1 score of 95.74% than other state-of-the-art algorithms (92.03%-93.66%) and improves to 97.44% with threshold strategy. The model achieves similar excellent performance on two external test sets from the same and different OCT machines. In human-model comparison, FMUE achieves a higher F1 score of 96.30% than retinal experts (86.95%, p = 0.004), senior doctors (82.71%, p < 0.001), junior doctors (66.55%, p < 0.001), and generative pretrained transformer 4 with vision (GPT-4V) (32.39%, p < 0.001). Besides, FMUE predicts high uncertainty scores for >85% images of non-target-category diseases or with low quality to prompt manual checks and prevent misdiagnosis. Our FMUE provides a trustworthy method for automatic retinal anomaly detection in a clinical open-set environment.

100 项与武汉爱尔眼科医院有限公司相关的药物交易

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100 项与武汉爱尔眼科医院有限公司相关的转化医学

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