Delving into the Latest Updates on Società Prodotti Antibiotici SpA with Synapse

概览

关联

2

项与 Società Prodotti Antibiotici SpA 相关的药物

SPK-843

靶点-

作用机制

细胞膜调节剂

在研机构-

原研机构

Società Prodotti Antibiotici SpA

在研适应症-

非在研适应症

曲霉菌病 [+3]

最高研发阶段终止

首次获批国家/地区-

首次获批日期-

Rifametane

靶点-

作用机制

蛋白质生物合成抑制剂

在研机构-

原研机构

Società Prodotti Antibiotici SpA

在研适应症-

非在研适应症

细菌感染

最高研发阶段无进展

首次获批国家/地区-

首次获批日期-

3

项与 Società Prodotti Antibiotici SpA 相关的临床试验

NCT06263517

/ Recruiting临床2/3期

Adaptative, Multicenter, Randomized, Double-blind, Parallel-group, Placebo Controlled, Clinical Trial, on the Efficacy and Tolerability of Different Escalating Doses of Intra-articular Clodronate in Patients With Painful Knee Osteoarthritis

The goal of this clinical trial is to to clarify which is the best dose of administration, to select a dose and to confirm the therapeutic efficacy of clodronate in patients with painful knee osteoarthritis (OA). The clinical trial will be divided in two parts.
The main questions it aims to answer are:
in Phase II, to assess the safety and tolerability of different escalating doses of intra articular (IA) clodronate
in Phase II, to set a defined therapeutic dose (DTD) to be used in Phase III
in Phase III, to assess the safety and tolerability of different escalating doses of IA clodronate to confirm and extensively evaluate the therapeutic efficacy and safety of the clodronate DTD in patients with knee OA

开始日期2023-10-12

申办/合作机构

Società Prodotti Antibiotici SpA

EUCTR2009-013274-41-IT

/ Unknown statusN/A

Multicenter, randomized, parallel group open study to compare, in patients with postmenopausal osteoporosis, the effects of clodronate (Difosfonal) administered either intramuscularly at a dose of 100 mg 1 weekly, intramuscularly at a dose of 200 mg once every 2 weeks or orally at a dose of 800 mg daily (400 mg x 2), on BMD and markers of bone metabolism. - ND

开始日期2010-05-10

申办/合作机构

Società Prodotti Antibiotici SpA

EUCTR2005-004969-41-IT

/ Not yet recruitingN/A

A double-blind, controlled vs placebo trial to evaluate the efficacy of EPA and DHA ethyl esters, in addition to usual antiarrhythmic therapy, in the manintenance of synus rythm in patients candidate to electrical cardioversion of persistent atrial fibrillation. - EPA and DHA in FA after electrical cardioversion

开始日期2006-02-14

申办/合作机构

Società Prodotti Antibiotici SpA

100 项与 Società Prodotti Antibiotici SpA 相关的临床结果

登录后查看更多信息

0 项与 Società Prodotti Antibiotici SpA 相关的专利（医药）

登录后查看更多信息

4

项与 Società Prodotti Antibiotici SpA 相关的文献（医药）

Arzneimittel-Forschung

Synthesis and laxative properties of 4,4'-(2-picolylidene)bis[phenylphosphoric acid]

作者: Bruzzese, T. ; Goi, A. ; Riva, M.

The title compound (I) was prepared by reaction of the alc. II with POCl3 in pyridine and subsequent alk. hydrolysis.I had the same laxative effect in rats as the acetyl and sulfonyl compounds III and IV.In time of intestinal evacuation, the rate was in the order: III > I > IV.

Bollettino Chimico Farmaceutico

In vitro diffusion studies of some polyene antibiotics with a three-phase partition apparatus

作者: Gazzaniga, A. ; Petracci, S. ; Mozzi, G.

The behavior of a series of new polyene antibiotics derived from partricin A was studied using a suitable apparatus, consisting of a triphasic water/oil/water system for the in vitro evaluation of the diffusion characteristics.The transport rate constant from the donor aqueous phase to the receiving aqueous phase, through the oil phase, was found to be directly proportional to the concentration of the test product in the donor aqueous phase, inversely proportional to the pH values of the aqueous phases and directly proportional to the oil/water partition coefficient of the various polyenes considered.Information was thus obtained about the possible in vivo behavior of the series of products considered, which would prove helpful in planning further more extensive and more thorough investigations on a restricted number of mols.

Research Communications in Chemical Pathology and Pharmacology

Lysozyme, intradermal diffusion of India ink and peritoneal capillary permeability in mice

作者: Ronchini, Alessandro ; Goi, Anna ; Bianchi, Camillo

Hen egg white lysozyme [9001-63-2] injected intracutaneously into mice inhibits the intradermal diffusion of India Ink.The effect of lysozyme persists in presence of hyaluronidase.Lysozyme injected i.p. into mice inhibits acetic acid-induced leakage of Pontamine Sky Blue into the abdominal cavity.Apparently, lysozyme may have applications outside the microbiol. field.

100 项与 Società Prodotti Antibiotici SpA 相关的药物交易

登录后查看更多信息

100 项与 Società Prodotti Antibiotici SpA 相关的转化医学

登录后查看更多信息