"We executed a robust and well-controlled phase 2a study of EVO101 designed to show significant improvement over standard of care, and this allowed us to make an efficient decision based on the data," CEO Luis Peña said in the Sept. 27 release.
IRAK4 continues to be a target of interest for pharma. Gilead Sciences handed over $20 million upfront in March to license an IRAK4 degrader from Nurix only a month after the Big Pharma dropped two of the three indications being explored for its IRAK4 inhibitorIRAK4 inhibitor called GS-5718.
With EVO101 out of the picture, Evommune will “focus its resources on advancing its pipeline of systemically administered product candidates which have multiple milestones expected over the next several years.”
With the biotech sharing plans to launch EVO756 into the clinic in early 2024, Maruho has clearly seen potential. The company has licensed the rights to develop and commercialize the asset in Japan for a total of $60 million in combined upfront and potential milestone payments, Evommune added in today’s release.